Associate Professor of Internal Medicine
Associate Professor of Human Genetics
Associate Chair
Department of Human Genetics and Program Director
Human Genetics
[email protected]
Available to mentor
JoAnn M Sekiguchi
Associate Professor
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Hartlerode AJ, Mostafa AM, Orban SK, Benedeck R, Campbell K, Hoenerhoff MJ, Ferguson DO, Sekiguchi JM. Hum Mol Genet, 2024 Sep 3; 33 (18): 1605 - 1617.Journal ArticleReduced levels of MRE11 cause disease phenotypes distinct from ataxia telangiectasia-like disorder.
DOI:10.1093/hmg/ddae101 PMID: 38888340 -
Melnick AF, Mullin C, Lin K, McCarter AC, Liang S, Liu YE, Wang Q, Jerome NA, Choe E, Kunnath N, Bodanapu G, Akter F, Magnuson B, Kumar S, Lombard DB, Muntean AG, Ljungman M, Sekiguchi J, Ryan RJH, Chiang MY. Blood, 2023 Dec 21; 142 (25): 2159 - 2174.Journal ArticleCdc73 protects Notch-induced T-cell leukemia cells from DNA damage and mitochondrial stress.
DOI:10.1182/blood.2023020144 PMID: 37616559 -
Dorta-Estremera SM, Peterson EA, Pérez-Santiago J, Sekiguchi JM. Front Immunol, 2023 14: 1269020Journal ArticleEditorial: Interplay between oncomicrobes, the microbiota and the immune system: impact on responses to cancer immunotherapy.
DOI:10.3389/fimmu.2023.1269020 PMID: 37654498 -
Saunders RA, Michniacki TF, Hames C, Moale HA, Wilke C, Kuo ME, Nguyen J, Hartlerode AJ, Moore BB, Sekiguchi JM. Sci Rep, 2021 Feb 19; 11 (1): 4268Journal ArticleElevated inflammatory responses and targeted therapeutic intervention in a preclinical mouse model of ataxia-telangiectasia lung disease.
DOI:10.1038/s41598-021-83531-3 PMID: 33608602 -
Wang K, Ahmed S, Sartor MA, Corfas G, Hammoud SS, Sekiguchi JM, Kidd JM, Glover TW, Wilson TE. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 2020 61: 54 - 54.Proceeding / Abstract / PosterA Robust Analysis Pipeline for Lineage-based Detection of Mosaic Copy Number Variants in Single Cells.
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Wang K, Ahmed S, Sartor MA, Corfas G, Hammoud SS, Sekiguchi JM, Kidd JM, Glover TW, Wilson TE. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 2020 61: 90 - 90.Proceeding / Abstract / PosterA Robust Analysis Pipeline for Lineage-based Detection of Mosaic Copy Number Variants in Single Cells.
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Spehalski E, Capper KM, Smith CJ, Morgan MJ, Dinkelmann M, Buis J, Sekiguchi JM, Ferguson DO. Cancer Res, 2017 Oct 1; 77 (19): 5327 - 5338.Journal ArticleMRE11 Promotes Tumorigenesis by Facilitating Resistance to Oncogene-Induced Replication Stress.
DOI:10.1158/0008-5472.CAN-17-1355 PMID: 28819025 -
Ku C-J, Sekiguchi JM, Panwar B, Guan Y, Takahashi S, Yoh K, Maillard I, Hosoya T, Engel JD. Mol Cell Biol, 2017 Jun 15; 37 (12):Journal ArticleGATA3 Abundance Is a Critical Determinant of T Cell Receptor β Allelic Exclusion.
DOI:10.1128/MCB.00052-17 PMID: 28320875
Department News
Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.
Department News
Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.
