John F Greden

John F. Greden
Professor Emeritus of Psychiatry and Research Professor Emeritus, Michigan Neuroscience Institute, Medical School
[email protected]
Available to mentor
John F Greden
John F. Greden
Professor Emeritus/a
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  • Center Memberships

    • Center Member
      Eisenberg Family Depression Center
    • Center Member
      AI and Digital Health Innovation

    Recent Publications

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    • Journal Article
      111. Modulation of GABA Synthesis by Intravenous Racemic Ketamine in Treatment-Resistant Major Depressive Disorder: Insights From the NNDC Bio-K Multicenter Trial
      Singh B, MahmoudianDehkordi S, Fogaca M, Voort JLV, Parikh S, Achtyes E, Goes F, Scaini G, Port J, Bobo W, Greden J, Frye M, Kaddurah-Daouk R. Biological Psychiatry, 2026 Apr 28; 99 (10): s147 DOI:10.1016/j.biopsych.2026.03.345
    • Journal Article
      198. Plasma Lactate as a Metabolic Predictor of Ketamine Response in Treatment-Resistant Depression
      Scaini G, Gusmao CTP, Tamez MCC, Cordeiro RC, de Quevedo J, Tye S, Elmallakh R, Parikh S, Bobo W, Goes FS, Voort JLV, Nykamp L, Balwinder S, Nelson E, Thase M, Frye M, Greden J, Achtyes E. Biological Psychiatry, 2026 Apr 28; 99 (10): s183 - s184. DOI:10.1016/j.biopsych.2026.03.432
    • Journal Article
      Utilizing depression symptom-based phenotypes to explore ketamine treatment response in major depression: The bio-K multicenter trial
      Penaluna BK, Vande Voort JL, Bobo WV, Pazdernik V, Achtyes ED, Goes FS, Greden JF, Parikh SV, Frye MA, Singh B. Journal of Affective Disorders, 2025 Sep 15; 385: DOI:10.1016/j.jad.2025.119414
      PMID: 40381857
    • Journal Article
      High Baseline Plasma Anthranilic Acid Predicts Remission Upon Acute-Series Ketamine Infusion for Treatment-Resistant Depression
      Murata SA, Madaj ZB, Capan CD, Sheldon RD, El-Mallakh RS, Parikh SV, Bobo WV, Goes FS, Wolkowitz OM, Vande Voort JL, Nykamp LJ, Singh B, Medeiros GC, Nelson EB, Thase ME, Oxenkrug GF, Frye MA, Greden JF, Achtyes ED, Brundin LC. Biological Psychiatry Global Open Science, 2025 Jul 1; 5 (4): DOI:10.1016/j.bpsgos.2025.100503
    • Journal Article
      Change in neurocognitive functioning in patients with treatment-resistant depression with serial intravenous ketamine infusions: The Bio-K multicenter trial.
      Singh B, Parikh SV, Voort JLV, Pazdernik VK, Achtyes ED, Goes FS, Yocum AK, Nykamp L, Becerra A, Smart L, Greden JF, Bobo WV, Frye MA, Burdick KE, Ryan KA. Psychiatry Res, 2024 May; 335: 115829 DOI:10.1016/j.psychres.2024.115829
      PMID: 38479192
    • Journal Article
      Clinical outcomes in the biomarkers of ketamine (Bio-K) study of open-label IV ketamine for refractory depression
      Parikh SV, Vande Voort JL, Yocum AK, Achtyes E, Goes FS, Nykamp L, Singh B, Lopez-Vives D, Sera CE, Maixner D, Tarnal V, Severe J, Bartek S, Tye SJ, Rico J, Stoppel CJ, Becerra A, Smart LA, Miller CR, Frye MA, Greden JF, Bobo WV. Journal of Affective Disorders, 2024 Mar 1; 348: 143 - 151. DOI:10.1016/j.jad.2023.12.033
      PMID: 38142892
    • Proceeding / Abstract / Poster
      Change in Neurocognitive Functioning in Patients with Treatment-Resistant Depression with Serial Intravenous Ketamine Infusions: The Bio-K Multicenter Trial
      Balwinder S, Parikh S, Vande Voort J, Pazdernick V, Yocum A, Achtyes E, Goes F, Greden J, Bobo W, Burdick K, Frye M, Ryan K. 2023 Oct 12;
    • Journal Article
      Patients' recovery and non-recovery narratives after intravenous ketamine for treatment-resistant depression
      Lapidos A, Lopez-Vives D, Sera CE, Ahearn E, Vest E, Senic I, Vande Voort JL, Frye M, Goes FS, Achtyes E, Greden J, Parikh SV. Journal of Affective Disorders, 2023 Feb 15; 323: 534 - 539. DOI:10.1016/j.jad.2022.11.090
      PMID: 36481228

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