John F Greden
Professor Emeritus of Psychiatry and Research Professor Emeritus
Michigan Neuroscience Institute
Medical School
Email:
[email protected]
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Available to mentor
John F Greden
Professor Emeritus/a
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Center Memberships
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Center MemberEisenberg Family Depression Center
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Center MemberAI and Digital Health Innovation
Recent Publications
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Singh B, MahmoudianDehkordi S, Fogaca M, Voort JLV, Parikh S, Achtyes E, Goes F, Scaini G, Port J, Bobo W, Greden J, Frye M, Kaddurah-Daouk R. Biological Psychiatry, 2026 Apr 28; 99 (10): s147Journal Article111. Modulation of GABA Synthesis by Intravenous Racemic Ketamine in Treatment-Resistant Major Depressive Disorder: Insights From the NNDC Bio-K Multicenter Trial
DOI:10.1016/j.biopsych.2026.03.345 -
Scaini G, Gusmao CTP, Tamez MCC, Cordeiro RC, de Quevedo J, Tye S, Elmallakh R, Parikh S, Bobo W, Goes FS, Voort JLV, Nykamp L, Balwinder S, Nelson E, Thase M, Frye M, Greden J, Achtyes E. Biological Psychiatry, 2026 Apr 28; 99 (10): s183 - s184.Journal Article198. Plasma Lactate as a Metabolic Predictor of Ketamine Response in Treatment-Resistant Depression
DOI:10.1016/j.biopsych.2026.03.432 -
Singh B, MahmoudianDehkordi S, Vande Voort JL, Parikh SV, Achtyes ED, Goes FS, Bobo WV, Greden JF, Scaini G, Tye S, Frye MA, Kaddurah-Daouk R. World Journal of Biological Psychiatry, 2026 Jan 1;Journal ArticleMetabolomic correlates of intravenous racemic ketamine in treatment-resistant major depressive disorder: the Bio-K/NNDC multicenter trial
DOI:10.1080/15622975.2026.2724510 PMID: 42702010 -
Penaluna BK, Vande Voort JL, Bobo WV, Pazdernik V, Achtyes ED, Goes FS, Greden JF, Parikh SV, Frye MA, Singh B. Journal of Affective Disorders, 2025 Sep 15; 385:Journal ArticleUtilizing depression symptom-based phenotypes to explore ketamine treatment response in major depression: The bio-K multicenter trial
DOI:10.1016/j.jad.2025.119414 PMID: 40381857 -
Murata SA, Madaj ZB, Capan CD, Sheldon RD, El-Mallakh RS, Parikh SV, Bobo WV, Goes FS, Wolkowitz OM, Vande Voort JL, Nykamp LJ, Singh B, Medeiros GC, Nelson EB, Thase ME, Oxenkrug GF, Frye MA, Greden JF, Achtyes ED, Brundin LC. Biological Psychiatry Global Open Science, 2025 Jul 1; 5 (4):Journal ArticleHigh Baseline Plasma Anthranilic Acid Predicts Remission Upon Acute-Series Ketamine Infusion for Treatment-Resistant Depression
DOI:10.1016/j.bpsgos.2025.100503 -
Singh B, Parikh SV, Voort JLV, Pazdernik VK, Achtyes ED, Goes FS, Yocum AK, Nykamp L, Becerra A, Smart L, Greden JF, Bobo WV, Frye MA, Burdick KE, Ryan KA. Psychiatry Res, 2024 May; 335: 115829Journal ArticleChange in neurocognitive functioning in patients with treatment-resistant depression with serial intravenous ketamine infusions: The Bio-K multicenter trial.
DOI:10.1016/j.psychres.2024.115829 PMID: 38479192 -
Parikh SV, Vande Voort JL, Yocum AK, Achtyes E, Goes FS, Nykamp L, Singh B, Lopez-Vives D, Sera CE, Maixner D, Tarnal V, Severe J, Bartek S, Tye SJ, Rico J, Stoppel CJ, Becerra A, Smart LA, Miller CR, Frye MA, Greden JF, Bobo WV. Journal of Affective Disorders, 2024 Mar 1; 348: 143 - 151.Journal ArticleClinical outcomes in the biomarkers of ketamine (Bio-K) study of open-label IV ketamine for refractory depression
DOI:10.1016/j.jad.2023.12.033 PMID: 38142892 -
Balwinder S, Parikh S, Vande Voort J, Pazdernick V, Yocum A, Achtyes E, Goes F, Greden J, Bobo W, Burdick K, Frye M, Ryan K. 2023 Oct 12;Proceeding / Abstract / PosterChange in Neurocognitive Functioning in Patients with Treatment-Resistant Depression with Serial Intravenous Ketamine Infusions: The Bio-K Multicenter Trial
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