1500 E Medical Center Drive
Ann Arbor, MI 48109
Available to mentor
Michael Mathis, MD is an Associate Professor of Anesthesiology in the Division of Adult Cardiac Anesthesia at the University of Michigan. After completing his undergraduate degree in Biomedical Engineering at Duke University in 2006, Dr. Mathis received his MD from University of Michigan in 2010 and completed his residency in Anesthesiology and fellowship in Adult Cardiothoracic Anesthesiology at University of Michigan. He also completed an NIH T32 research fellowship sponsored by the Department of Anesthesiology at University of Michigan.
Dr. Mathis seeks to improve perioperative care of patients with advanced cardiovascular disease, through the use of data science techniques applied to real-world electronic health data. He serves as the Research Director for the Multicenter Perioperative Outcomes Group spanning US academic and community hospitals, amassing data electronic anesthesiology records for research and quality improvement.
Multicenter Perioperative Outcomes Group
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MDUniversity of Michigan, 1500 East Medical Center Drive, 2010
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BSEDuke University, Durham, 2006
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Center MemberCenter for Computational Medicine and Bioinformatics
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Center MemberPrecision Health Initiative
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Center MemberInstitute for Healthcare Policy and Innovation
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Center Membere-Health and Artificial Intelligence Initiative
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Center MemberSamuel and Jean Frankel Cardiovascular Center
Dr. Mathis has research interests in improving perioperative care for patients with advanced cardiovascular disease, particularly for patients with heart failure. As part of the Multicenter Perioperative Outcomes Group (MPOG), an international consortium of perioperative databases for which U-M serves as the coordinating center, he serves as Research Director and plays a lead role in integration of MPOG data with data from national cardiac and thoracic surgery registries. He also has interests in leveraging novel data science methods to understand patterns within highly granular intraoperative physiologic data, studying hemodynamic responses to surgical and anesthetic stimuli as a means for early detection of cardiovascular diseases such as heart failure.
Dr. Mathis is an Affiliated Faculty within the Center of Computational Medicine and Bioinformatics (CCMB), member of the Michigan Integrated Center for Health Analytics & Medical Prediction (MiCHAMP) and member of the Institute for Health Policy and Innovation (IHPI). He has received research funding from the NIH, Department of Defense, and the BCBS Foundation of Michigan.
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Ebadi-Tehrani M, Sheu R, Alfirevic A, Kazanjian P, Zimmerman K, Mathis M, Swaminathan M, Mackensen GB, Nicoara A. J Cardiothorac Vasc Anesth, 2024 Mar; 38 (3): 616 - 625.Journal ArticlePractical Considerations for Obtaining Perioperative Transesophageal Echocardiography Accreditation: Collective Experiences at Early-Adopting Centers.
DOI:10.1053/j.jvca.2023.11.019 PMID: 38087669 -
Aziz MF, Schenning K, Koike S, O'Glasser A, O'Reilly-Shah VN, Sera V, Mathis M, Multicenter Perioperative Outcomes Group Investigators . Anesthesiology, 2024 Feb 1; 140 (2): 195 - 206.Journal ArticlePerioperative Mortality of the COVID-19 Recovered Patient Compared to a Matched Control: A Multicenter Retrospective Cohort Study.
DOI:10.1097/ALN.0000000000004809 PMID: 37844271 -
Templeton TW, Krol B, Miller S, Lee LK, Mathis M, Vishneski SR, Chatterjee D, Gupta R, Shroeder RA, Saha AK, Multicenter Perioperative Outcomes Group Investigators . Anesthesiology, 2024 Jan 1; 140 (1): 25 - 37.Journal ArticleHypoxemia in School-age Children Undergoing One-lung Ventilation: A Retrospective Cohort Study from the Multicenter Perioperative Outcomes Group.
DOI:10.1097/ALN.0000000000004781 PMID: 37738432 -
Kamyszek RW, Newman N, Ragheb JW, Sjoding MW, Joo H, Maile MD, Cassidy RB, Golbus JR, Michigan Congestive Heart Failure Investigators , Engoren MC, Mathis MR. J Clin Anesth, 2023 Nov; 90: 111226Journal ArticleDifferences between patients in whom physicians agree versus disagree about the preoperative diagnosis of heart failure.
DOI:10.1016/j.jclinane.2023.111226 PMID: 37549434 -
Lazzareschi DV, Fong N, Mavrothalassitis O, Whitlock EL, Chen CL, Chiu C, Adelmann D, Bokoch MP, Chen L-L, Liu KD, Pirracchio R, Mathis MR, Legrand M, MPOG Collaborators . Ann Surg, 2023 Oct 1; 278 (4): e745 - e753.Journal ArticleIntraoperative Use of Albumin in Major Noncardiac Surgery: Incidence, Variability, and Association With Outcomes.
DOI:10.1097/SLA.0000000000005774 PMID: 36521076 -
Kendale S, Bishara A, Burns M, Solomon S, Corriere M, Mathis M. JMIR AI, 2023 Sep 8;Journal ArticleMachine Learning for Prediction of Procedural Case Durations Developed Using a Large Multicenter Database: Algorithm Development and Validation (Preprint)
DOI:10.2196/44909 -
Zhang Y, Wittrup E, Najarian K, Mathis M. Research Square,PreprintEvolveFNN: An interpretable framework for early detection using longitudinal electronic health record data
DOI:10.21203/rs.3.rs-3314609/v1 -
Mathis MR, Janda AM, Kheterpal S, Schonberger RB, Pagani FD, Engoren MC, Mentz GB, Shook DC, Muehlschlegel JD, Multicenter Perioperative Outcomes Group . Anesthesiology, 2023 Aug 1; 139 (2): 122 - 141.Journal ArticlePatient-, Clinician-, and Institution-level Variation in Inotrope Use for Cardiac Surgery: A Multicenter Observational Analysis.
DOI:10.1097/ALN.0000000000004593 PMID: 37094103