Michael Mathis, MD
Associate Professor of Anesthesiology
Program Director, Anesthesiology
Anesthesiology
1500 E Medical Center Drive
Ann Arbor, MI 48109
[email protected]

Available to mentor

Michael Mathis, MD
Associate Professor
  • About
  • Links
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • About

    Michael Mathis, MD is an Associate Professor of Anesthesiology in the Division of Adult Cardiac Anesthesia at the University of Michigan. After completing his undergraduate degree in Biomedical Engineering at Duke University in 2006, Dr. Mathis received his MD from University of Michigan in 2010 and completed his residency in Anesthesiology and fellowship in Adult Cardiothoracic Anesthesiology at University of Michigan. He also completed an NIH T32 research fellowship sponsored by the Department of Anesthesiology at University of Michigan.

    Dr. Mathis seeks to improve perioperative care of patients with advanced cardiovascular disease, through the use of data science techniques applied to real-world electronic health data. He serves as the Research Director for the Multicenter Perioperative Outcomes Group spanning US academic and community hospitals, amassing data electronic anesthesiology records for research and quality improvement.

    Links
    • Multicenter Perioperative Outcomes Group
    Qualifications
    • MD
      University of Michigan, 1500 East Medical Center Drive, 2010
    • BSE
      Duke University, Durham, 2006
    Center Memberships
    • Center Member
      Center for Computational Medicine and Bioinformatics
    • Center Member
      Precision Health Initiative
    • Center Member
      Institute for Healthcare Policy and Innovation
    • Center Member
      e-Health and Artificial Intelligence Initiative
    • Center Member
      Samuel and Jean Frankel Cardiovascular Center
    Research Overview

    Dr. Mathis has research interests in improving perioperative care for patients with advanced cardiovascular disease, particularly for patients with heart failure. As part of the Multicenter Perioperative Outcomes Group (MPOG), an international consortium of perioperative databases for which U-M serves as the coordinating center, he serves as Research Director and plays a lead role in integration of MPOG data with data from national cardiac and thoracic surgery registries. He also has interests in leveraging novel data science methods to understand patterns within highly granular intraoperative physiologic data, studying hemodynamic responses to surgical and anesthetic stimuli as a means for early detection of cardiovascular diseases such as heart failure.

    Dr. Mathis is an Affiliated Faculty within the Center of Computational Medicine and Bioinformatics (CCMB), member of the Michigan Integrated Center for Health Analytics & Medical Prediction (MiCHAMP) and member of the Institute for Health Policy and Innovation (IHPI). He has received research funding from the NIH, Department of Defense, and the BCBS Foundation of Michigan.

    Recent Publications See All Publications
    • Journal Article
      Practical Considerations for Obtaining Perioperative Transesophageal Echocardiography Accreditation: Collective Experiences at Early-Adopting Centers.
      Ebadi-Tehrani M, Sheu R, Alfirevic A, Kazanjian P, Zimmerman K, Mathis M, Swaminathan M, Mackensen GB, Nicoara A. J Cardiothorac Vasc Anesth, 2024 Mar; 38 (3): 616 - 625. DOI:10.1053/j.jvca.2023.11.019
      PMID: 38087669
    • Journal Article
      Perioperative Mortality of the COVID-19 Recovered Patient Compared to a Matched Control: A Multicenter Retrospective Cohort Study.
      Aziz MF, Schenning K, Koike S, O'Glasser A, O'Reilly-Shah VN, Sera V, Mathis M, Multicenter Perioperative Outcomes Group Investigators . Anesthesiology, 2024 Feb 1; 140 (2): 195 - 206. DOI:10.1097/ALN.0000000000004809
      PMID: 37844271
    • Journal Article
      Hypoxemia in School-age Children Undergoing One-lung Ventilation: A Retrospective Cohort Study from the Multicenter Perioperative Outcomes Group.
      Templeton TW, Krol B, Miller S, Lee LK, Mathis M, Vishneski SR, Chatterjee D, Gupta R, Shroeder RA, Saha AK, Multicenter Perioperative Outcomes Group Investigators . Anesthesiology, 2024 Jan 1; 140 (1): 25 - 37. DOI:10.1097/ALN.0000000000004781
      PMID: 37738432
    • Journal Article
      Differences between patients in whom physicians agree versus disagree about the preoperative diagnosis of heart failure.
      Kamyszek RW, Newman N, Ragheb JW, Sjoding MW, Joo H, Maile MD, Cassidy RB, Golbus JR, Michigan Congestive Heart Failure Investigators , Engoren MC, Mathis MR. J Clin Anesth, 2023 Nov; 90: 111226 DOI:10.1016/j.jclinane.2023.111226
      PMID: 37549434
    • Journal Article
      Intraoperative Use of Albumin in Major Noncardiac Surgery: Incidence, Variability, and Association With Outcomes.
      Lazzareschi DV, Fong N, Mavrothalassitis O, Whitlock EL, Chen CL, Chiu C, Adelmann D, Bokoch MP, Chen L-L, Liu KD, Pirracchio R, Mathis MR, Legrand M, MPOG Collaborators . Ann Surg, 2023 Oct 1; 278 (4): e745 - e753. DOI:10.1097/SLA.0000000000005774
      PMID: 36521076
    • Journal Article
      Machine Learning for Prediction of Procedural Case Durations Developed Using a Large Multicenter Database: Algorithm Development and Validation (Preprint)
      Kendale S, Bishara A, Burns M, Solomon S, Corriere M, Mathis M. JMIR AI, 2023 Sep 8; DOI:10.2196/44909
    • Preprint
      EvolveFNN: An interpretable framework for early detection using longitudinal electronic health record data
      Zhang Y, Wittrup E, Najarian K, Mathis M. Research Square, DOI:10.21203/rs.3.rs-3314609/v1
    • Journal Article
      Patient-, Clinician-, and Institution-level Variation in Inotrope Use for Cardiac Surgery: A Multicenter Observational Analysis.
      Mathis MR, Janda AM, Kheterpal S, Schonberger RB, Pagani FD, Engoren MC, Mentz GB, Shook DC, Muehlschlegel JD, Multicenter Perioperative Outcomes Group . Anesthesiology, 2023 Aug 1; 139 (2): 122 - 141. DOI:10.1097/ALN.0000000000004593
      PMID: 37094103
    Featured News & Stories Michael Mathis
    Department News
    Michael Mathis, MD, awarded NIH grant to compare inotrope practice variation in cardiac surgery
    A new study led by Michael Mathis, MD, is setting out to better understand variation in inotrope decision-making and outcomes across hospitals, as well as the barriers and facilitators to inotrope practice change. Mathis recently received National Institutes of Health funding through the National Heart, Lung and Blood Institute to support this research.
    Department News
    Fourteen faculty promotions announced
    The University of Michigan Regents approved 14 Department of Anesthesiology faculty promotions during their May 2023 meeting. Promotions will go into effect September 1.
    Department News
    Department receives perioperative transesophageal echocardiography accreditation by IAC
    IAC accreditation is a “seal of approval” and indicator to patients of consistent quality care and a dedication to continuous improvement.