Michael Mathis, MD
Associate Professor of Anesthesiology and Program Director, Anesthesiology
Anesthesiology
1500 E Medical Center Drive
Ann Arbor, MI 48109
[email protected]

Available to mentor

Michael Mathis, MD
Associate Professor
  • About
  • Links
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • About

    Michael Mathis, MD is an Associate Professor of Anesthesiology in the Division of Adult Cardiac Anesthesia at the University of Michigan. After completing his undergraduate degree in Biomedical Engineering at Duke University in 2006, Dr. Mathis received his MD from University of Michigan in 2010 and completed his residency in Anesthesiology and fellowship in Adult Cardiothoracic Anesthesiology at University of Michigan. He also completed an NIH T32 research fellowship sponsored by the Department of Anesthesiology at University of Michigan.

    Dr. Mathis seeks to improve perioperative care of patients with advanced cardiovascular disease, through the use of data science techniques applied to real-world electronic health data. He serves as the Research Director for the Multicenter Perioperative Outcomes Group spanning US academic and community hospitals, amassing data electronic anesthesiology records for research and quality improvement.

    Links
    • Multicenter Perioperative Outcomes Group
    Qualifications
    • MD
      University of Michigan, 1500 East Medical Center Drive, 2010
    • BSE
      Duke University, Durham, 2006
    Center Memberships
    • Center Member
      Center for Computational Medicine and Bioinformatics
    • Center Member
      Precision Health Initiative
    • Center Member
      Institute for Healthcare Policy and Innovation
    • Center Member
      Samuel and Jean Frankel Cardiovascular Center
    • Center Member
      e-Health and Artificial Intelligence Initiative
    Research Overview

    Dr. Mathis has research interests in improving perioperative care for patients with advanced cardiovascular disease, particularly for patients with heart failure. As part of the Multicenter Perioperative Outcomes Group (MPOG), an international consortium of perioperative databases for which U-M serves as the coordinating center, he serves as Research Director and plays a lead role in integration of MPOG data with data from national cardiac and thoracic surgery registries. He also has interests in leveraging novel data science methods to understand patterns within highly granular intraoperative physiologic data, studying hemodynamic responses to surgical and anesthetic stimuli as a means for early detection of cardiovascular diseases such as heart failure.

    Dr. Mathis is an Affiliated Faculty within the Center of Computational Medicine and Bioinformatics (CCMB), member of the Michigan Integrated Center for Health Analytics & Medical Prediction (MiCHAMP) and member of the Institute for Health Policy and Innovation (IHPI). He has received research funding from the NIH, Department of Defense, and the BCBS Foundation of Michigan.

    Recent Publications See All Publications
    • Journal Article
      Anesthesia Techniques for Vitreoretinal Surgery in the United States: A Report from the Multicenter Perioperative Outcomes Group Research Consortium.
      Chauhan MZ, Soliman MK, Pace NL, Mathis MR, Schonberger RB, Sallam AB, MPOG Investigator Group . Am J Ophthalmol, 2024 Nov; 267: 30 - 40. DOI:10.1016/j.ajo.2024.06.010
      PMID: 38871268
    • Journal Article
      Association between inspired oxygen fraction and development of postoperative pulmonary complications in thoracic surgery: a multicentre retrospective cohort study.
      Douville NJ, Smolkin ME, Naik BI, Mathis MR, Colquhoun DA, Kheterpal S, Collins SR, Martin LW, Popescu WM, Pace NL, Blank RS, Multicentre Perioperative Clinical Research Committee . Br J Anaesth, 2024 Nov; 133 (5): 1073 - 1084. DOI:10.1016/j.bja.2024.08.005
      PMID: 39266439
    • Presentation
      AI for Research: Reasons that AI Research Implementations can Fail, and What to do About It
      Mathis M. 2024 Oct 22;
    • Journal Article
      Bronchial Blocker Versus Endobronchial Intubation in Young Children Undergoing One-Lung Ventilation: A Multicenter Retrospective Cohort Study.
      McLaughlin CS, Samant A, Saha AK, Lee LK, Gupta R, Templeton LB, Mathis MR, Vishneski S, Templeton TW, Multicenter Perioperative Outcomes Group . Anesth Analg, 2024 Sep 12; DOI:10.1213/ANE.0000000000006973
      PMID: 39269648
    • Journal Article
      Polygenic Score for the Prediction of Postoperative Nausea and Vomiting: A Retrospective Derivation and Validation Cohort Study.
      Douville NJ, Bastarache L, He J, Wu K-HH, Vanderwerff B, Bertucci-Richter E, Hornsby WE, Lewis A, Jewell ES, Kheterpal S, Shah N, Mathis M, Engoren MC, Douville CB, Surakka I, Willer C, Kertai MD. Anesthesiology, 2024 Sep 9; DOI:10.1097/ALN.0000000000005214
      PMID: 39250560
    • Journal Article
      Shedding Needed Light on a Black Box Approach to Prediction of Hypotension.
      Vistisen ST, London MJ, Mathis MR, van Klei WA, Huzurbazar S, Jacquet-Lagrèze M. Anesthesiology, 2024 Sep 1; 141 (3): 421 - 424. DOI:10.1097/ALN.0000000000005099
      PMID: 39136478
    • Journal Article
      The Association of Oxygen Delivery and Transfusion on Cardiopulmonary Bypass with Acute Kidney Injury.
      Engoren M, Janda A, Heung M, Sturmer D, Likosky DS, Hawkins RB, Do-Nguyen CC, Mathis M. J Cardiothorac Vasc Anesth, 2024 Sep; 38 (9): 1914 - 1922. DOI:10.1053/j.jvca.2024.04.019
      PMID: 38890088
    • Journal Article
      A Comparison of Interpretable Machine Learning Approaches to Identify Outpatient Clinical Phenotypes Predictive of First Acute Myocardial Infarction.
      Hodgman M, Minoccheri C, Mathis M, Wittrup E, Najarian K. Diagnostics (Basel), 2024 Aug 10; 14 (16): DOI:10.3390/diagnostics14161741
      PMID: 39202229
    Featured News & Stories Michael Mathis
    Department News
    Michael Mathis, MD, awarded NIH grant to compare inotrope practice variation in cardiac surgery
    A new study led by Michael Mathis, MD, is setting out to better understand variation in inotrope decision-making and outcomes across hospitals, as well as the barriers and facilitators to inotrope practice change. Mathis recently received National Institutes of Health funding through the National Heart, Lung and Blood Institute to support this research.
    Department News
    Fourteen faculty promotions announced
    The University of Michigan Regents approved 14 Department of Anesthesiology faculty promotions during their May 2023 meeting. Promotions will go into effect September 1.
    Department News
    Department receives perioperative transesophageal echocardiography accreditation by IAC
    IAC accreditation is a “seal of approval” and indicator to patients of consistent quality care and a dedication to continuous improvement.