1500 E Medical Center Drive
Ann Arbor, MI 48109
Available to mentor
Michael Mathis, MD is an Associate Professor of Anesthesiology in the Division of Adult Cardiac Anesthesia at the University of Michigan. After completing his undergraduate degree in Biomedical Engineering at Duke University in 2006, Dr. Mathis received his MD from University of Michigan in 2010 and completed his residency in Anesthesiology and fellowship in Adult Cardiothoracic Anesthesiology at University of Michigan. He also completed an NIH T32 research fellowship sponsored by the Department of Anesthesiology at University of Michigan.
Dr. Mathis seeks to improve perioperative care of patients with advanced cardiovascular disease, through the use of data science techniques applied to real-world electronic health data. He serves as the Research Director for the Multicenter Perioperative Outcomes Group spanning US academic and community hospitals, amassing data electronic anesthesiology records for research and quality improvement.
Multicenter Perioperative Outcomes Group
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MDUniversity of Michigan, 1500 East Medical Center Drive, 2010
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BSEDuke University, Durham, 2006
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Center MemberCenter for Computational Medicine and Bioinformatics
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Center MemberPrecision Health Initiative
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Center MemberInstitute for Healthcare Policy and Innovation
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Center MemberSamuel and Jean Frankel Cardiovascular Center
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Center Membere-Health and Artificial Intelligence Initiative
Dr. Mathis has research interests in improving perioperative care for patients with advanced cardiovascular disease, particularly for patients with heart failure. As part of the Multicenter Perioperative Outcomes Group (MPOG), an international consortium of perioperative databases for which U-M serves as the coordinating center, he serves as Research Director and plays a lead role in integration of MPOG data with data from national cardiac and thoracic surgery registries. He also has interests in leveraging novel data science methods to understand patterns within highly granular intraoperative physiologic data, studying hemodynamic responses to surgical and anesthetic stimuli as a means for early detection of cardiovascular diseases such as heart failure.
Dr. Mathis is an Affiliated Faculty within the Center of Computational Medicine and Bioinformatics (CCMB), member of the Michigan Integrated Center for Health Analytics & Medical Prediction (MiCHAMP) and member of the Institute for Health Policy and Innovation (IHPI). He has received research funding from the NIH, Department of Defense, and the BCBS Foundation of Michigan.
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Chauhan MZ, Soliman MK, Pace NL, Mathis MR, Schonberger RB, Sallam AB, MPOG Investigator Group . Am J Ophthalmol, 2024 Nov; 267: 30 - 40.Journal ArticleAnesthesia Techniques for Vitreoretinal Surgery in the United States: A Report from the Multicenter Perioperative Outcomes Group Research Consortium.
DOI:10.1016/j.ajo.2024.06.010 PMID: 38871268 -
Douville NJ, Smolkin ME, Naik BI, Mathis MR, Colquhoun DA, Kheterpal S, Collins SR, Martin LW, Popescu WM, Pace NL, Blank RS, Multicentre Perioperative Clinical Research Committee . Br J Anaesth, 2024 Nov; 133 (5): 1073 - 1084.Journal ArticleAssociation between inspired oxygen fraction and development of postoperative pulmonary complications in thoracic surgery: a multicentre retrospective cohort study.
DOI:10.1016/j.bja.2024.08.005 PMID: 39266439 -
Mathis M. 2024 Oct 22;PresentationAI for Research: Reasons that AI Research Implementations can Fail, and What to do About It
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McLaughlin CS, Samant A, Saha AK, Lee LK, Gupta R, Templeton LB, Mathis MR, Vishneski S, Templeton TW, Multicenter Perioperative Outcomes Group . Anesth Analg, 2024 Sep 12;Journal ArticleBronchial Blocker Versus Endobronchial Intubation in Young Children Undergoing One-Lung Ventilation: A Multicenter Retrospective Cohort Study.
DOI:10.1213/ANE.0000000000006973 PMID: 39269648 -
Douville NJ, Bastarache L, He J, Wu K-HH, Vanderwerff B, Bertucci-Richter E, Hornsby WE, Lewis A, Jewell ES, Kheterpal S, Shah N, Mathis M, Engoren MC, Douville CB, Surakka I, Willer C, Kertai MD. Anesthesiology, 2024 Sep 9;Journal ArticlePolygenic Score for the Prediction of Postoperative Nausea and Vomiting: A Retrospective Derivation and Validation Cohort Study.
DOI:10.1097/ALN.0000000000005214 PMID: 39250560 -
Vistisen ST, London MJ, Mathis MR, van Klei WA, Huzurbazar S, Jacquet-Lagrèze M. Anesthesiology, 2024 Sep 1; 141 (3): 421 - 424.Journal ArticleShedding Needed Light on a Black Box Approach to Prediction of Hypotension.
DOI:10.1097/ALN.0000000000005099 PMID: 39136478 -
Engoren M, Janda A, Heung M, Sturmer D, Likosky DS, Hawkins RB, Do-Nguyen CC, Mathis M. J Cardiothorac Vasc Anesth, 2024 Sep; 38 (9): 1914 - 1922.Journal ArticleThe Association of Oxygen Delivery and Transfusion on Cardiopulmonary Bypass with Acute Kidney Injury.
DOI:10.1053/j.jvca.2024.04.019 PMID: 38890088 -
Hodgman M, Minoccheri C, Mathis M, Wittrup E, Najarian K. Diagnostics (Basel), 2024 Aug 10; 14 (16):Journal ArticleA Comparison of Interpretable Machine Learning Approaches to Identify Outpatient Clinical Phenotypes Predictive of First Acute Myocardial Infarction.
DOI:10.3390/diagnostics14161741 PMID: 39202229