Michael J Imperiale, PhD
Arthur F Thurnau Professor Emeritus
Professor Emeritus of Microbiology and Immunology
Medical School
University of Michigan–Ann Arbor
Microbiology and Immunology
1150 W Medical Center Dr
Ann Arbor, MI 48109
[email protected]
Microbiology and Immunology
1150 W Medical Center Dr
Ann Arbor, MI 48109
Available to mentor
Michael J Imperiale, PhD
Professor Emeritus/a
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Qualifications
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Postdoctoral FellowRockefeller University, Laboratory of Molecular Cell Biology, New York, United States
1981 - 1984
Postdoctoral Fellowship
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PhDColumbia University, New York, United States
1981
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MPhilColumbia University, New York, United States
1979
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MAColumbia University, New York, United States
1978
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BAColumbia University, New York, United States
1972 - 1976
Center Memberships
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Center MemberRogel Cancer Center
Research Overview
* Virus replication
* Virus-host cell interactions
* Science policy with a focus on biosecurity
* Research Integrity
Recent Publications
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Imperiale MJ, Casadevall A. mSphere, 2026 Jun 11; e0034226Journal ArticleMirror microbial life and the dual use dilemma.
DOI:10.1128/msphere.00342-26 PMID: 42274247 -
Yuan W, Haley SA, Imperiale MJ, Atwood WJ. Viruses, 2026 May 19; 18 (5):Journal ArticleLiving on the Edge: The Goldilocks Zone of Polyomavirus Replication and Persistence.
DOI:10.3390/v18050571 PMID: PMC13211360 -
Marvin T, Sealfon R, McCown PJ, AlAkwaa F, Farkash EA, Otto EA, Eichinger F, An P, Menon R, Berthier CC, Reed TJ, Arrowsmith P, Subramanian L, Shaffer KJ, Norman SP, Gumber R, Imperiale MJ, Pipas JM, Troyanskaya OG, Kretzler M, Theesfeld CL, Naik AS. JCI Insight, 2026 Mar 12;Journal ArticleSingle-cell Analysis of Human Kidney Biopsy Tissue Reveals Epithelial and Immune Cell Responses to BK Polyomavirus Infection.
DOI:10.1172/jci.insight.198227 PMID: 41818285 -
Bloomfield D, Black JRM, Crook O, Brandes N, Hanke MS, Inglesby TV, Cicero A, Pollack R, Hernandez-Boussard T, Imperiale MJ, Altman RB, Pannu J. Science New York N Y, 2026 Feb 5; 391 (6785): 558 - 561.Journal ArticleBiological data governance in an age of AI
DOI:10.1126/science.aeb2689 PMID: 41643006 -
Blader I, Goodrum F, Imperiale MJ, Casadevall A, Arias CA, Baumler A, Burnham CAD, Cuomo CA, Detweiler CS, Forrest GN, Gilbert JA, Lovett S, Maloy S, McAdam A, Newton I, Reguera G, O'Toole GA, Schloss PD, Shade A, Whiteley M. Clinical Microbiology Reviews, 2025 Jun 1; 38 (2):Journal ArticleA call for the United States to continue investing in science
DOI:10.1128/cmr.00044-25 PMID: 40013868 -
Imperiale MJ. Msphere, 2025 Jun 1; 10 (6):Journal ArticleFinal reflections
DOI:10.1128/msphere.00345-25 PMID: 40470937 -
Imperiale MJ. Applied Biosafety, 2025 Jun 1; 30 (2): 143 - 145.Journal ArticleIncorporating the Intent of the Experiment into Gain-of-Function Oversight
DOI:10.1089/apb.2025.0008 -
Imperiale MJ, Casadevall A. Msphere, 2025 Jun 1; 10 (6):Journal ArticleTwo golden anniversaries in the biological sciences
DOI:10.1128/msphere.00240-25 PMID: 40366186
Featured News & Stories
Department News
Mike Imperiale is Professor Emeritus of M&I
In January 2024, Michael J. Imperiale, PhD, Arthur F. Thurnau Professor, started his tenure as Professor Emeritus after his retirement from the University of Michigan (U-M) Department of Microbiology and Immunology (M&I) in December 2023.
Department News
Michael Imperiale is on NPR
Michael Imperiale is on NPR