George A Mashour
Senior Associate Dean for Faculty and Faculty Development
Professor of Anesthesiology
Program Director, Anesthesiology
Professor of Pharmacology
[email protected]

Available to mentor
George A Mashour
Senior Associate Dean
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
    • Qualifications
    • MD, PhD
      Georgetown University, Washington D.C.
    Center Memberships
    • Center Member
      Center for Integrative Research in Critical Care
    Research Overview

    Multidisciplinary approaches to the study of consciousness
    - Network mechanisms of consciousness and unconsciousness
    -Theories of consciousness
    - Interfaces of sleep neurobiology and general anesthesia
    - Intraoperative awareness and metrics of consciousness

    Recent Publications See All Publications
    • Journal Article
      Measuring the dynamic balance of integration and segregation underlying consciousness, anesthesia, and sleep in humans.
      Jang H, Mashour GA, Hudetz AG, Huang Z. Nat Commun, 2024 Oct 24; 15 (1): 9164 DOI:10.1038/s41467-024-53299-x
      PMID: 39448600
    • Journal Article
      Propofol disrupts the functional core-matrix architecture of the thalamus in humans.
      Huang Z, Mashour GA, Hudetz AG. Nat Commun, 2024 Sep 9; 15 (1): 7496 DOI:10.1038/s41467-024-51837-1
      PMID: 39251579
    • Preprint
      Preliminary safety and effectiveness of psilocybin-assisted therapy in adults with fibromyalgia: An open-label, proof-of-concept clinical trial
      Aday JS, McAfee J, Conroy DA, Hosanagar A, Tarnal V, Weston C, Scott K, Horowitz D, Harte SE, Pouyan N, Glynos NG, Baker AK, Guss J, Davis AK, Burgess HJ, Mashour GA, Clauw DJ, Boehnke KF. PsyArXiv, DOI:10.31234/osf.io/j8zb5
    • Preprint
      Thalamic Roles in Conscious Perception Revealed by Low-Intensity Focused Ultrasound Neuromodulation.
      Jang H, Fotiadis P, Mashour GA, Hudetz AG, Huang Z. 2024 Oct 10; DOI:10.1101/2024.10.07.617034
      PMID: 39416133
    • Preprint
      Regulation of REM Sleep Onset and Homeostasis by Preoptic Glutamatergic Neurons
      Mondino A, Jadidian A, Toth B, Hambrecht-Wiedbusch VS, Floran-Garduno L, Li D, York AK, Torterolo P, Pal D, Burgess C, Mashour GA, Vanini G. bioRxiv, DOI:10.1101/2024.10.03.616573
    • Journal Article
      Sachin Kheterpal, M.D., M.B.A., Recipient of the 2024 Award for Excellence in Research
      Mashour GA. Anesthesiology, 2024 Oct 1; 141 (4): 652 - 653. DOI:10.1097/aln.0000000000005140
    • Journal Article
      Classifying Unconscious, Psychedelic, and Neuropsychiatric Brain States with Functional Connectivity, Graph Theory, and Cortical Gradient Analysis.
      Jang H, Dai R, Mashour GA, Hudetz AG, Huang Z. Brain Sci, 2024 Aug 30; 14 (9): DOI:10.3390/brainsci14090880
      PMID: 39335376
    • Journal Article
      Anesthesia and the neurobiology of consciousness.
      Mashour GA. Neuron, 2024 May 15; 112 (10): 1553 - 1567. DOI:10.1016/j.neuron.2024.03.002
      PMID: 38579714
    Featured News & Stories brain drawn
    Health Lab
    The brain in balance
    In a recent study, using network neuroscience, investigators found a way to objectively determine the balance of integration and segregation in fMRI-measured brain signals during wakefulness as well as during sleep and anesthesia.
         88% Reduction in GHG Emissions
    Department News
    Green Anesthesia Initiative exceeds lofty goals for reduction in emissions
    The Department of Anesthesiology’s Green Anesthesia Initiative (GAIA) has taken an ambitious approach to environmental sustainability resulting in an 88% reduction of inhaled anesthetic greenhouse gas emissions.
    Department News
    George Mashour, MD, PhD, featured on the StarTalk Podcast
    George Mashour, MD, PhD at the University of Michigan Department of Anesthesiology featured on the StarTalk Podcast.
    Department News
    Green Anesthesia Initiative quickly shows progress
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         Research By the Numbers FY22.jpg
    Department News
    U-M Anesthesiology ranked #1 in NIH funding for eighth consecutive year with more than $22M in funding
    Three researchers — Drs. George Mashour, Chad Brummett, and David Williams — ranked in top 7 for PI funding.
    Department News
    Department of Anesthesiology launches initiative to minimize the field’s impact on climate change
    The initiative aims to reduce the Department of Anesthesiology's greenhouse gas emissions from anesthetic gases by 80%.