George A Mashour
Senior Associate Dean for Faculty and Faculty Development
Professor of Anesthesiology
Program Director, Anesthesiology
Professor of Pharmacology
[email protected]

Available to mentor
George A Mashour
Senior Associate Dean
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
    • Qualifications
    • MD, PhD
      Georgetown University, Washington D.C.
    Center Memberships
    • Center Member
      Center for Integrative Research in Critical Care
    Research Overview

    Multidisciplinary approaches to the study of consciousness
    - Network mechanisms of consciousness and unconsciousness
    -Theories of consciousness
    - Interfaces of sleep neurobiology and general anesthesia
    - Intraoperative awareness and metrics of consciousness

    Recent Publications See All Publications
    • Journal Article
      Propofol disrupts the functional core-matrix architecture of the thalamus in humans.
      Huang Z, Mashour GA, Hudetz AG. Nat Commun, 2024 Sep 9; 15 (1): 7496 DOI:10.1038/s41467-024-51837-1
      PMID: 39251579
    • Journal Article
      Comparative Electroencephalographic Profile of a New Anesthetic and Anticonvulsant That Is Selective for the GABAAR Slow Receptor Subtype
      Maciver MB, McCarren HS, Eagleman SL, Davies FM, Jahangir A, Pal D, Mashour GA, Bertaccini EJ. Anesthesia & Analgesia, DOI:10.1213/ane.0000000000007178
    • Preprint
      Regulation of REM Sleep Onset and Homeostasis by Preoptic Glutamatergic Neurons
      Mondino A, Jadidian A, Toth B, Hambrecht-Wiedbusch VS, Floran-Garduno L, Li D, York AK, Torterolo P, Pal D, Burgess C, Mashour GA, Vanini G. bioRxiv, DOI:10.1101/2024.10.03.616573
    • Journal Article
      Sachin Kheterpal, M.D., M.B.A., Recipient of the 2024 Award for Excellence in Research
      Mashour GA. Anesthesiology, 2024 Oct 1; 141 (4): 652 - 653. DOI:10.1097/aln.0000000000005140
    • Journal Article
      Classifying Unconscious, Psychedelic, and Neuropsychiatric Brain States with Functional Connectivity, Graph Theory, and Cortical Gradient Analysis.
      Jang H, Dai R, Mashour GA, Hudetz AG, Huang Z. Brain Sci, 2024 Aug 30; 14 (9): DOI:10.3390/brainsci14090880
      PMID: 39335376
    • Journal Article
      Anesthesia and the neurobiology of consciousness.
      Mashour GA. Neuron, 2024 May 15; 112 (10): 1553 - 1567. DOI:10.1016/j.neuron.2024.03.002
      PMID: 38579714
    • Journal Article
      Effect of Inactivation of Prefrontal Cortex on Sleep-Wake States in Rat
      Ponnaluri S, Groenhout T, Sharba L, Liu T, Mashour GA, Pal D. Physiology, 2024 May; 39 (S1): 1146 DOI:10.1152/physiol.2024.39.s1.1146
    • Journal Article
      Effect of Intravenous Delivery of N,N Dimethyltryptamine on Sleep-Wake States in Rat
      Summerfield R, Groenhout T, Liu T, Vanini G, Mashour GA, Pal D. Physiology, 2024 May; 39 (S1): 1145 DOI:10.1152/physiol.2024.39.s1.1145
    Featured News & Stories brain drawn
    Health Lab
    The brain in balance
    In a recent study, using network neuroscience, investigators found a way to objectively determine the balance of integration and segregation in fMRI-measured brain signals during wakefulness as well as during sleep and anesthesia.
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    The Department of Anesthesiology’s Green Anesthesia Initiative (GAIA) has taken an ambitious approach to environmental sustainability resulting in an 88% reduction of inhaled anesthetic greenhouse gas emissions.
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    Department News
    U-M Anesthesiology ranked #1 in NIH funding for eighth consecutive year with more than $22M in funding
    Three researchers — Drs. George Mashour, Chad Brummett, and David Williams — ranked in top 7 for PI funding.
    Department News
    Department of Anesthesiology launches initiative to minimize the field’s impact on climate change
    The initiative aims to reduce the Department of Anesthesiology's greenhouse gas emissions from anesthetic gases by 80%.