J Brian Fowlkes, PhD
Radiology
6428B Medical Sciences Building I
Ann Arbor, Michigan 48109-2026
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About
J. Brian Fowlkes, PhD, is Professor of Radiology and Biomedical Engineering at the University of Michigan. He joined the U of M in 1988 where he directs research in ultrasound for diagnostic and therapeutic applications. His work includes investigation of acoustic droplet vaporization, utilization of gas bubbles in high intensity ultrasound including histotripsy, volume flow estimation from 3D color flow imaging, and assessment of urinary tract function using ultrasound imaging and contrast agents.
Dr. Fowlkes is a Fellow and former President of the American Institute of Ultrasound in Medicine (AIUM). He is recipient of the Joseph H. Holmes Pioneer Award for Basic Science from the AIUM. Dr. Fowlkes is a Fellow of the American Institute of Medical and Biomedical Engineering (AIMBE), the Acoustical Society of America (ASA), the American Association of Physicists in Medicine (AAPM) and the Institute of Electrical and Electronics Engineers (IEEE).
Links
Radiology Ultrasound Laboratory
Qualifications
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Postdoctoral FellowshipUniversity of Michigan, Radiology, Ann Arbor, United States
1988 - 1991
Postdoctoral Fellowship
Center Memberships
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Center MemberGlobal REACH
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Center MemberWeil Institute for Critical Care Research
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Center MemberMM-PKUHSC Joint Institute
Research Overview
* Acoustic droplet vaporization for bubble production in therapeutic ultrasound and drug release
* Effects of gas bubbles in high intensity ultrasound including histotripsy
* Volumetric blood flow estimation using 3D/4D ultrasonic imaging
* Biomedical Imaging, Biomedical Ultrasonics and Image-Guided Therapy
Recent Publications
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Fowlkes JB, Akiyama I, Bader K, ter Haar G, Harris G, Miloro P, Moran CM, Nomura J, Verma P, Wear K, Whalley G. Ultrasound in Medicine and Biology, 2026 Nov 1; 52 (11): 2305 - 2307.Journal ArticleRecommended Maximum Exposure Times for Displayed Thermal Index (TI) Values
DOI:10.1016/j.ultrasmedbio.2026.05.022 PMID: 42624731 -
Poul D, Betancourt AR, Samal A, Quesada C, Lynch T, Baiu C, Fowlkes JB, Chan HL, Kripfgans OD. Ultrasound in Medicine and Biology, 2026 Oct 1; 52 (10): 2213 - 2224.Journal ArticleFirst Standard Quantification of Ultrasound Attenuation in Healthy Periodontal Soft Tissues In Vivo
DOI:10.1016/j.ultrasmedbio.2026.06.010 PMID: 42414192 -
Poul D, Betancourt AR, Samal A, Quesada C, Lynch T, Baiu C, Fowlkes JB, Chan H-L, Kripfgans OD. 2026 Sep 23; arXiv,PreprintBuccal-Lingual Analysis and Inflammation Tracking in Oral Soft Tissues Using Quantitative Ultrasound: A Preclinical Study
DOI:10.48550/arxiv.2609.23931 -
Tai H, Worlikar T, Xu Z, Fowlkes J, Shi J, Zhang M. Academic Radiology, 2026 Sep 1; 33 (9): 3948 - 3958.Journal ArticleQuantification of Histotripsy Dosage Using Machine Learning-Enhanced Ultrasound Imaging Analysis: Correlation with Histological Outcomes
DOI:10.1016/j.acra.2026.05.010 PMID: 42270524 -
Kalayeh K, Fowlkes JB, Sack BS, Schultz WW, Schmidt P, Ashton-Miller JA, DeLancey JO. 2026 Sep 17;PatentUltrasound motion tracking to measure movement of structures in the pelvic area
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Kalayeh K, DeLancey JOL, Ashton-Miller JA, Fowlkes JB. Measurement Science and Technology, 2026 Aug 1; 37 (32):Journal ArticleMechanically-induced fiducial marker system for event-based synchronization of independent recording instruments
DOI:10.1088/1361-6501/ae92a4 -
Poul D, Betancourt AR, Samal A, Quesada C, Lynch T, Baiu C, Fowlkes JB, Chan H-L, Kripfgans OD. 2026 Jul 9; arXiv,PreprintLongitudinal Monitoring of Periodontal Inflammation by Quantitative Ultrasound: Attenuation and Backscatter Intensity Signature
DOI:10.48550/arxiv.2607.05676 -
Poul D, Betancourt AR, Samal A, Quesada C, Lynch T, Baiu C, Fowlkes JB, Chan H-L, Kripfgans OD. 2026 Mar 25; arXiv,PreprintFirst Standard Quantification of Ultrasound Attenuation in Healthy Periodontal Soft Tissues In Vivo
DOI:10.48550/arxiv.2603.22189
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