J Brian Fowlkes, PhD
Radiology
6428B Medical Sciences Building I
Ann Arbor, Michigan 48109-2026
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About
J. Brian Fowlkes, PhD, is Professor of Radiology and Biomedical Engineering at the University of Michigan. He joined the U of M in 1988 where he directs research in ultrasound for diagnostic and therapeutic applications. His work includes investigation of acoustic droplet vaporization, utilization of gas bubbles in high intensity ultrasound including histotripsy, volume flow estimation from 3D color flow imaging, and assessment of urinary tract function using ultrasound imaging and contrast agents.
Dr. Fowlkes is a Fellow and former President of the American Institute of Ultrasound in Medicine (AIUM). He is recipient of the Joseph H. Holmes Pioneer Award for Basic Science from the AIUM. Dr. Fowlkes is a Fellow of the American Institute of Medical and Biomedical Engineering (AIMBE), the Acoustical Society of America (ASA), the American Association of Physicists in Medicine (AAPM) and the Institute of Electrical and Electronics Engineers (IEEE).
Links
Radiology Ultrasound Laboratory
Qualifications
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Postdoctoral FellowshipUniversity of Michigan, Radiology, Ann Arbor, United States
1988 - 1991
Postdoctoral Fellowship
Center Memberships
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Center MemberGlobal REACH
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Center MemberWeil Institute for Critical Care Research
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Center MemberMM-PKUHSC Joint Institute
Research Overview
* Acoustic droplet vaporization for bubble production in therapeutic ultrasound and drug release
* Effects of gas bubbles in high intensity ultrasound including histotripsy
* Volumetric blood flow estimation using 3D/4D ultrasonic imaging
* Biomedical Imaging, Biomedical Ultrasonics and Image-Guided Therapy
Recent Publications
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Fowlkes JB, Akiyama I, Bader K, Ter Haar G, Harris G, Miloro P, Moran CM, Nomura J, Verma P, Wear K, Whalley G. Ultrasound Med Biol, 2026 Aug 20;Journal ArticleRecommended Maximum Exposure Times for Displayed Thermal Index (TI) Values.
DOI:10.1016/j.ultrasmedbio.2026.05.022 PMID: 42624731 -
Kalayeh K, DeLancey JOL, Ashton-Miller JA, Fowlkes JB. Meas Sci Technol, 2026 Aug 14; 37 (32): 325903Journal ArticleMechanically-induced fiducial marker system for event-based synchronization of independent recording instruments.
DOI:10.1088/1361-6501/ae92a4 PMID: PMC13463179 -
Poul D, Betancourt AR, Samal A, Quesada C, Lynch T, Baiu C, Fowlkes JB, Chan H-L, Kripfgans OD. Ultrasound Med Biol, 2026 Jul 7;Journal ArticleFirst Standard Quantification of Ultrasound Attenuation in Healthy Periodontal Soft Tissues In Vivo.
DOI:10.1016/j.ultrasmedbio.2026.06.010 PMID: 42414192 -
Poul D, Betancourt AR, Samal A, Quesada C, Lynch T, Baiu C, Fowlkes JB, Chan H-L, Kripfgans OD. 2026 Jul 9; arXiv,PreprintLongitudinal Monitoring of Periodontal Inflammation by Quantitative Ultrasound: Attenuation and Backscatter Intensity Signature
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Poul D, Betancourt AR, Samal A, Quesada C, Lynch T, Baiu C, Fowlkes JB, Chan H-L, Kripfgans OD. 2026 Mar 25; arXiv,PreprintFirst Standard Quantification of Ultrasound Attenuation in Healthy Periodontal Soft Tissues In Vivo
DOI:10.48550/arxiv.2603.22189 -
Kalayeh K, Sui W, Zhang M, Zhang M, Brace CL, Grimes MD, Tripathy P, Hall TJ, Mendez IR, Fowlkes JB, Wells SA. Journal of Urology, 2026 Apr 30; 215 (5S): e320Journal ArticleIP15-06 PROSTATE TRANSITION ZONE STIFFNESS MEASURED BY ULTRASOUND SHEAR WAVE ELASTOGRAPHY VARIES ACROSS CLINICAL BPH/LUTS PHENOTYPES: A FEASIBILITY STUDY
DOI:10.1097/01.ju.0001191356.52697.6d.06 -
Kalayeh K, Heroux G, LaCross J, Ashton-Miller J, DeLancey J, Fowlkes J. 2026 May 17;Proceeding / Abstract / PosterQuantifying Pelvic Floor Coordination via Automated Motion Onset Detection in Transperineal Ultrasound
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Spiekhout S, Abeid BA, Estrada JB, Fowlkes JB, Fabiilli ML, Aliabouzar M. Ultrasonics Sonochemistry, 2026 May 1; 128:Journal ArticleReal-time drug release monitoring from acoustically responsive scaffolds
DOI:10.1016/j.ultsonch.2026.107806 PMID: 41795411
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