J Brian Fowlkes, PhD
Radiology
6428B Medical Sciences Building I
Ann Arbor, Michigan 48109-2026
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About
J. Brian Fowlkes, PhD, is Professor of Radiology and Biomedical Engineering at the University of Michigan. He joined the U of M in 1988 where he directs research in ultrasound for diagnostic and therapeutic applications. His work includes investigation of acoustic droplet vaporization, utilization of gas bubbles in high intensity ultrasound including histotripsy, volume flow estimation from 3D color flow imaging, and assessment of urinary tract function using ultrasound imaging and contrast agents.
Dr. Fowlkes is a Fellow and former President of the American Institute of Ultrasound in Medicine (AIUM). He is recipient of the Joseph H. Holmes Pioneer Award for Basic Science from the AIUM. Dr. Fowlkes is a Fellow of the American Institute of Medical and Biomedical Engineering (AIMBE), the Acoustical Society of America (ASA), the American Association of Physicists in Medicine (AAPM) and the Institute of Electrical and Electronics Engineers (IEEE).
Links
Radiology Ultrasound Laboratory
Qualifications
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Postdoctoral FellowshipUniversity of Michigan, Radiology, Ann Arbor, United States
1988 - 1991
Postdoctoral Fellowship
Center Memberships
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Center MemberGlobal REACH
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Center MemberWeil Institute for Critical Care Research
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Center MemberMM-PKUHSC Joint Institute
Research Overview
* Acoustic droplet vaporization for bubble production in therapeutic ultrasound and drug release
* Effects of gas bubbles in high intensity ultrasound including histotripsy
* Volumetric blood flow estimation using 3D/4D ultrasonic imaging
* Biomedical Imaging, Biomedical Ultrasonics and Image-Guided Therapy
Recent Publications
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Poul D, Betancourt AR, Samal A, Quesada C, Lynch T, Baiu C, Fowlkes JB, Chan H-L, Kripfgans OD. 2026 Mar 25; arXiv,PreprintFirst Standard Quantification of Ultrasound Attenuation in Healthy Periodontal Soft Tissues In Vivo
DOI:10.48550/arxiv.2603.22189 -
Kalayeh K, Heroux G, LaCross J, Ashton-Miller J, DeLancey J, Fowlkes J. 2026 May 17;Proceeding / Abstract / PosterQuantifying Pelvic Floor Coordination via Automated Motion Onset Detection in Transperineal Ultrasound
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Heroux G, LaCross J, DeLancey J, Fowlkes J, Ashton-Miller J, Kalayeh K. 2026 Mar 18;Proceeding / Abstract / PosterPoint-of-Care Urethral Mobility Assessment: Adapting Motion Tracking to Handheld Ultrasound
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Spiekhout S, Abeid BA, Estrada JB, Fowlkes JB, Fabiilli ML, Aliabouzar M. Ultrasonics Sonochemistry, 2026 Mar 4; 107806 - 107806.Journal ArticleReal-time drug release monitoring from acoustically responsive scaffolds
DOI:10.1016/j.ultsonch.2026.107806 -
Kalayeh K, Fowlkes JB, Daignault-Newton S, Schmidt P, Ashton-Miller JA, DeLancey JO. Neurourol Urodyn, 2026 Feb 9;Journal ArticleAutomated Ultrasound-Based Analysis of Urethral Kinematics in Stress Urinary Incontinence: A Pilot Study.
DOI:10.1002/nau.70231 PMID: 41657287 -
Kalayeh K, Heroux G, LaCross J, Ashton-Miller J, DeLancey J, Fowlkes J. 2026 Feb 18;Proceeding / Abstract / PosterAutomated Detection of Pelvic floor Motion Onset in Transperineal Ultrasound: A Proof of Concept Study
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Abdolmanafi A, Rubin J, Pinter SZ, Fowlkes JB, Kripfgans O. Biomed Phys Eng Express, 2026 Jan 29;Journal ArticleStatistical modeling of blood and tissue signatures using ultrasonic color flow imaging.
DOI:10.1088/2057-1976/ae3f36 PMID: 41610454 -
Tai H, Worlikar T, Xu Z, Fowlkes J, Shi J, Zhang M. Academic Radiology, 2026 Jan 1;Journal ArticleQuantification of Histotripsy Dosage Using Machine Learning-Enhanced Ultrasound Imaging Analysis: Correlation with Histological Outcomes
DOI:10.1016/j.acra.2026.05.010
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