Sami J Barmada, MD, PhD
Angela Dobson Welch and Lyndon Welch Research Professor
Associate Professor of Neurology
Medical School
[email protected]

Available to mentor

Sami J Barmada, MD, PhD
Associate Professor
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    Center Memberships
    • Center Member
      Taubman Institute
    • Center Member
      Center for Computational Medicine and Bioinformatics
    • Center Member
      Caswell Diabetes Institute
    Recent Publications See All Publications
    • Presentation
      TDP43 mislocalization in ALS and frontotemporal dementia
      Barmada S. 2025 Mar 11;
    • Journal Article
      Psychotropic medication usage in sporadic versus genetic behavioral-variant frontotemporal dementia
      Vargas-Gonzalez JC, Dimal N, Cortez K, Heuer H, Forsberg LK, Appleby BS, Barmada S, Bozoki A, Clark D, Cobigo Y, Darby RR, Dickerson BC, Domoto-Reilly K, Galasko DR, Geschwind DH, Ghoshal N, Graff-Radford NR, Grant IM, Irwin D, Hsiung GYR, Honig LS, Kantarci K, Léger GC, Litvan I, Mackenzie IR, Masdeu JC, Mendez MF, Onyike CU, Pascual B, Pressman P, Ramos EM, Roberson ED, Rogalski E, Boeve BF, Boxer AL, Rosen HJ, Tartaglia MC. Alzheimer's and Dementia, 2025 Feb 1; 21 (2): DOI:10.1002/alz.14448
      PMID: 39713899
    • Preprint
      Nemo-like kinase disrupts nuclear import and drives TDP43 mislocalization in ALS.
      Bekier ME, Pinarbasi E, Mesojedec JJ, Ghaffari L, de Majo M, Ullian E, Koontz M, Coleman S, Li X, Tank EMH, Waksmacki J, Barmada S. 2025 Jan 28; DOI:10.1101/2025.01.27.635090
      PMID: 39975323
    • Journal Article
      TDP43 autoregulation gives rise to dominant negative isoforms that are tightly controlled by transcriptional and post-translational mechanisms
      Dykstra MM, Weskamp K, Gómez NB, Waksmacki J, Tank E, Glineburg MR, Snyder A, Pinarbasi E, Bekier M, Li X, Miller MR, Bai J, Shahzad S, Nedumaran N, Wieland C, Stewart C, Willey S, Grotewold N, McBride J, Moran JJ, Suryakumar AV, Lucas M, Tessier PM, Ward M, Todd PK, Barmada SJ. Cell Reports, 2025 Jan 28; 44 (1): DOI:10.1016/j.celrep.2024.115113
      PMID: 39792557
    • Journal Article
      Neuropsychiatric symptoms cluster and fluctuate over time in behavioral variant frontotemporal dementia
      Morrow CB, Kamath V, Dickerson BC, Eldaief M, Rezaii N, Wong B, McGinnis S, Darby R, Staffaroni AM, Lapid MI, Pascual B, Rojas JC, Masdeu JC, Tsapkini K, Huey ED, Fisher DW, Pantelyat A, Balaji A, Sah E, Litvan I, Rascovsky K, Ghoshal N, Domoto-Reilly K, Kornak J, Onyike CU, Abdullah M, Apostolova L, Appleby B, Barmada S, Bayram E, Boeve B, Botha H, Boxer AL, Bozoki A, Brushaber D, Clark D, Considine CM, Darby RR, Day GS, Dickerson B, Dickson D, Domoto-Reilly K, Dwosh E, Faber K, Fagan A, Fields JA, Fong JC, Foroud T, Forsberg LK, Galasko DR, Gavrilova R, Gendron T, Geschwind D, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant IM, Grossman M, Hales CM, Hall M, Heuer HW, Honig LS, Ging-Yuek H, Huang E, Huey ED, Irwin D, Johnson N, Jones DT, Kantarci K, Knopman D, Kolander T, Kornak J, Kremers W, Kwan J, Lago AL, Lapid M, Lavigne SB, Lee S, Léger GC, Litvan I, Ljubenkov P, Lucente D, Mackenzie IR, Masdeu JC, Massimo L, McGinnis S, McMillan CT, Mendez MF, Mester C, Miyagawa T, Molden J, Onyike C, Pantelyat A, Pascual B, Paulson H, Petrucelli L, Pressman P, Rademakers R, Ramanan V. Psychiatry and Clinical Neurosciences, 2025 Jan 1; DOI:10.1111/pcn.13810
      PMID: 40079430
    • Journal Article
      <i>ABCA1</i> missense mutations are associated with Lewy body dementia
      Ray A, Reho P, Logroscino G, Barmada S, Ross OA, Scholz SW, Consortium ILBDG. Alzheimer's &amp; Dementia, 2025 Feb 3; 20 (S1): DOI:10.1002/alz.092678
    • Presentation
      TDP43 dysregulation and mislocalization in ALS and frontotemporal dementia
      Barmada S. 2025 Mar 11;
    • Journal Article
      Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and alter their functional properties.
      Mohan HM, Fernandez MG, Huang C, Lin R, Ryou JH, Seyfried D, Grotewold N, Whiteley AM, Barmada SJ, Basrur V, Mosalaganti S, Paulson HL, Sharkey LM. bioRxiv, 2024 Oct 25; DOI:10.1101/2024.10.24.620053
      PMID: PMC11527177
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