
Angela Dobson Welch and Lyndon Welch Research Professor
Associate Professor of Neurology
Medical School
[email protected]
Available to mentor
Sami J Barmada, MD, PhD

Associate Professor
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Center MemberTaubman Institute
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Center MemberCenter for Computational Medicine and Bioinformatics
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Center MemberCaswell Diabetes Institute
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Barmada S. 2025 Mar 11;PresentationTDP43 mislocalization in ALS and frontotemporal dementia
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Vargas-Gonzalez JC, Dimal N, Cortez K, Heuer H, Forsberg LK, Appleby BS, Barmada S, Bozoki A, Clark D, Cobigo Y, Darby RR, Dickerson BC, Domoto-Reilly K, Galasko DR, Geschwind DH, Ghoshal N, Graff-Radford NR, Grant IM, Irwin D, Hsiung GYR, Honig LS, Kantarci K, Léger GC, Litvan I, Mackenzie IR, Masdeu JC, Mendez MF, Onyike CU, Pascual B, Pressman P, Ramos EM, Roberson ED, Rogalski E, Boeve BF, Boxer AL, Rosen HJ, Tartaglia MC. Alzheimer's and Dementia, 2025 Feb 1; 21 (2):Journal ArticlePsychotropic medication usage in sporadic versus genetic behavioral-variant frontotemporal dementia
DOI:10.1002/alz.14448 PMID: 39713899 -
Bekier ME, Pinarbasi E, Mesojedec JJ, Ghaffari L, de Majo M, Ullian E, Koontz M, Coleman S, Li X, Tank EMH, Waksmacki J, Barmada S. 2025 Jan 28;PreprintNemo-like kinase disrupts nuclear import and drives TDP43 mislocalization in ALS.
DOI:10.1101/2025.01.27.635090 PMID: 39975323 -
Dykstra MM, Weskamp K, Gómez NB, Waksmacki J, Tank E, Glineburg MR, Snyder A, Pinarbasi E, Bekier M, Li X, Miller MR, Bai J, Shahzad S, Nedumaran N, Wieland C, Stewart C, Willey S, Grotewold N, McBride J, Moran JJ, Suryakumar AV, Lucas M, Tessier PM, Ward M, Todd PK, Barmada SJ. Cell Reports, 2025 Jan 28; 44 (1):Journal ArticleTDP43 autoregulation gives rise to dominant negative isoforms that are tightly controlled by transcriptional and post-translational mechanisms
DOI:10.1016/j.celrep.2024.115113 PMID: 39792557 -
Morrow CB, Kamath V, Dickerson BC, Eldaief M, Rezaii N, Wong B, McGinnis S, Darby R, Staffaroni AM, Lapid MI, Pascual B, Rojas JC, Masdeu JC, Tsapkini K, Huey ED, Fisher DW, Pantelyat A, Balaji A, Sah E, Litvan I, Rascovsky K, Ghoshal N, Domoto-Reilly K, Kornak J, Onyike CU, Abdullah M, Apostolova L, Appleby B, Barmada S, Bayram E, Boeve B, Botha H, Boxer AL, Bozoki A, Brushaber D, Clark D, Considine CM, Darby RR, Day GS, Dickerson B, Dickson D, Domoto-Reilly K, Dwosh E, Faber K, Fagan A, Fields JA, Fong JC, Foroud T, Forsberg LK, Galasko DR, Gavrilova R, Gendron T, Geschwind D, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant IM, Grossman M, Hales CM, Hall M, Heuer HW, Honig LS, Ging-Yuek H, Huang E, Huey ED, Irwin D, Johnson N, Jones DT, Kantarci K, Knopman D, Kolander T, Kornak J, Kremers W, Kwan J, Lago AL, Lapid M, Lavigne SB, Lee S, Léger GC, Litvan I, Ljubenkov P, Lucente D, Mackenzie IR, Masdeu JC, Massimo L, McGinnis S, McMillan CT, Mendez MF, Mester C, Miyagawa T, Molden J, Onyike C, Pantelyat A, Pascual B, Paulson H, Petrucelli L, Pressman P, Rademakers R, Ramanan V. Psychiatry and Clinical Neurosciences, 2025 Jan 1;Journal ArticleNeuropsychiatric symptoms cluster and fluctuate over time in behavioral variant frontotemporal dementia
DOI:10.1111/pcn.13810 PMID: 40079430 -
Ray A, Reho P, Logroscino G, Barmada S, Ross OA, Scholz SW, Consortium ILBDG. Alzheimer's & Dementia, 2025 Feb 3; 20 (S1):Journal Article<i>ABCA1</i> missense mutations are associated with Lewy body dementia
DOI:10.1002/alz.092678 -
Barmada S. 2025 Mar 11;PresentationTDP43 dysregulation and mislocalization in ALS and frontotemporal dementia
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Mohan HM, Fernandez MG, Huang C, Lin R, Ryou JH, Seyfried D, Grotewold N, Whiteley AM, Barmada SJ, Basrur V, Mosalaganti S, Paulson HL, Sharkey LM. bioRxiv, 2024 Oct 25;Journal ArticleEndogenous retrovirus-like proteins recruit UBQLN2 to stress granules and alter their functional properties.
DOI:10.1101/2024.10.24.620053 PMID: PMC11527177

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