Grace Chen, MD, PhD

 Grace chen
Professor of Internal Medicine, Medical School
Email:
[email protected]
Available to mentor
Grace Chen, MD, PhD
Grace chen
Professor
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  • Recent Publications

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    • Center Memberships
    • Center Member
      Rogel Cancer Center

    Recent Publications

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    • Journal Article
      Depleting luminal cysteine with engineered bacteroides vulgatus alleviates experimental colitis by suppressing Th17 differentiation through an ATF6-dependent mechanism
      Wang J, Tian ZX, Chen S, Chen GY, Wang YP, Wang P. Inflammation Research, 2026 Dec 1; 75 (1): DOI:10.1007/s00011-026-02341-3
      PMID: 42700252
    • Journal Article
      Loss of salivary agglutinin induces changes in the salivary microbiome and accelerates development of oral cancer
      de Medeiros MC, Fontaine S, Danella E, Hillman E, Schmidt TM, Furgal A, Wellik DM, Inohara N, Núñez G, Li G, Chen GY, D’Silva NJ. Microbiome, 2026 Dec 1; 14 (1): DOI:10.1186/s40168-026-02337-5
      PMID: 41964098
    • Journal Article
      Oral nano-delivery of a gut microbial metabolite enhances T cell stemness for cancer immunotherapy
      Han K, Cho YS, Takahashi M, Zhou X, Dobson HE, Hutchings K, Wu Y, Na Y, Xie F, Crowther J, Wu J, Xu J, Lee C, Jasewicz H, Kim Y, Nenwani M, Animasahun O, Wuchu F, Andren A, Wong H, Camp E, Wan Z, Wu Q, Zhang L, Xu C, Dong K, Xu Y, Schwendeman A, Chen GY, Xie Y, Lyssiotis CA, Clasby M, Nagrath D, Lei YL, Moon JJ. Nature Nanotechnology, 2026 Sep 1; 21 (9): 1338 - 1349. DOI:10.1038/s41565-026-02235-9
      PMID: 42575976
    • Journal Article
      Central role of IL-10 in CNS-protection from Inflammatory Damage during Cryptococcus Meningoencephalitis 2253926
      Hissong R, Li H, Goughenour K, Barnett J, Lintner M, Ballesteros A, Queen H, Ganguly A, Chen G, Xu J, Olszewski M. The Journal of Immunology, 2026 Jul 29; 215 (Supplement_1): vkag141.198 DOI:10.1093/jimmun/vkag141.198
    • Journal Article
      NLRP6 regulates donor T cell activation and acute graft-versus-host disease via ZAP-70-Erk pathway.
      Matsuki E, Miyata M, Sato R, Gawron J, Suto M, Tamaki H, Fujiwara H, Ito A, Hishima T, Ishizawa Y, Sekiguchi E, Tobai T, Ushio S, Oravecz-Wilson K, Chen G, Tawara I, Ichikawa K, Watanabe M, Ishizawa K, Yokoyama H, Peltier D, Blazar B, Zeiser R, Reddy P, Toubai T. Haematologica, 2026 Jul 2; DOI:10.3324/haematol.2025.289144
      PMID: 42389810
    • Preprint
      Locally sparse varying coefficient mixed model with application to longitudinal microbiome differential abundance
      Fontaine S, D'Silva NJ, de Medeiros MC, Chen GY, Zhu J, Li G. 2026 Jan 20; arXiv, DOI:10.48550/arxiv.2601.10872
    • Journal Article
      An innovative organoid model to screen for bacteria and their metabolites that protect against inflammation-induced colonic barrier disruption
      Cady N, Meyer SR, Kim K, Lo BC, So N, Chen GY, Rosshart SP, Shah YM, Núñez G, Sexton JZ, Schmidt TM. Msphere, 2026 Jan 1; 11 (8): 1 - 15. DOI:10.1128/msphere.00926-25
      PMID: 42536076
    • Journal Article
      NLRP6 regulates ZAP-70-erk signaling in both murine and human T cells and influences acute graft-versus-host disease(GVHD)
      Matsuki E, Miyata M, Gawron J, Suto M, Tamaki H, Fujiwara H, Ishizawa Y, Sekiguchi E, Tobai T, Ushio S, Oravecz-Wilson K, Chen G, Tawara I, Ichikawa K, Watanabe M, Ishizawa K, Yokoyama H, Peltier D, Blazar B, Zeiser R, Reddy P, Toubai T. Blood, 2025 Dec 6; 146 (Supplement 1): 4090 DOI:10.1182/blood-2025-4090