Rami Khoriaty, MD

Profile-RamiKhoriaty-2023
Associate Professor of Internal Medicine
Associate Professor of Cell and Developmental Biology
Medical School
Available to mentor
Rami Khoriaty, MD
Profile-RamiKhoriaty-2023
Associate Professor
  • Center Memberships
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  • Center Memberships

    • Center Member
      Rogel Cancer Center
    • Center Member
      Center for Cell Plasticity and Organ Design

    Recent Publications

    See All Publications
    • Journal Article
      Lipid Metabolism Transcriptomic Signature of Defective Erythropoiesis in Diamond Blackfan Anemia syndrome.
      Deng K, Wang Y, Min JC, Liu X, Ueharu H, Myers G, Yu L, Hammoud SB, Adam A, Saba R, Natogi V, Drysdale C, Chen B, Yee JL, Kitzman J, Lyssiotis CA, Mishina Y, Jones MA, Kaartinen V, Guan Y, Khoriaty R, Engel JD, Singh SA. Blood Adv, 2026 Jan 23; DOI:10.1182/bloodadvances.2025017318
      PMID: 41576344
    • Journal Article
      The hematopoietic stem cell MYB enhancer is essential for and recurrently amplified during T cell leukemogenesis
      Mullin C, Lin K, Choe E, Sha C, Shukla Z, Campbell K, McCarter AC, Wang A, Nieves-Salva J, Khan S, Keeley TM, Liang S, Wang Q, Melnick AF, Evans P, Monovich AC, Iyer A, Kodgule R, Deng Y, da Veiga Leprevost F, Barnett KR, Pölönen P, Khoriaty R, Savic D, Teachey DT, Mullighan CG, Cieslik M, Nesvizhskii AI, Samuelson LC, Jones M, Li Q, Ryan RJH, Chiang MY. Journal of Clinical Investigation, 2026 Jan 16; 136 (2): 1 - 17. DOI:10.1172/JCI189830
    • Journal Article
      The hematopoietic stem cell MYB enhancer is essential for and recurrently amplified during T cell leukemogenesis
      Mullin C, Lin K, Choe E, Sha C, Shukla Z, Campbell K, McCarter AC, Wang A, Nieves-Salva J, Khan S, Keeley TM, Liang S, Wang Q, Melnick AF, Evans P, Monovich AC, Iyer A, Kodgule R, Deng Y, da Veiga Leprevost F, Barnett KR, Pölönen P, Khoriaty R, Savic D, Teachey DT, Mullighan CG, Cieslik M, Nesvizhskii AI, Samuelson LC, Jones M, Li Q, Ryan RJ, Chiang MY. Journal of Clinical Investigation, 2026 Jan 2; 136 (1): DOI:10.1172/JCI187998
      PMID: 41129262
    • Journal Article
      p27Kip1regulates γ-globin production
      Balbin-Cuesta G, Drysdale C, Kerpet C, Yu L, Myers G, Lin Z, McGee B, Friedman A, Liu X, Singh SA, Engel JD, Buttitta L, Khoriaty R. Blood, 2026 Jan 1; DOI:10.1182/blood.2025028895
      PMID: 41411145
    • Journal Article
      A genome-wide screen identifies genes required for erythroid differentiation
      Myers G, Friedman A, Yu L, Pourmandi N, Kerpet C, Ito MA, Saba R, Tang V, Ozel AB, Bergin IL, Johnson CN, Ku CJ, Wang Y, Balbin-Cuesta G, Lim KC, Lin Z, Drysdale C, McGee B, Kurita R, Nakamura Y, Liu X, Siemieniak D, Singh SA, Lyssiotis CA, Maillard I, Weisman LS, Engel JD, Khoriaty R. Nature Communications, 2025 Dec 1; 16 (1): DOI:10.1038/s41467-025-58739-w
      PMID: 40221460
    • Proceeding / Abstract / Poster
      A genome-wide CRISPR activation screen identifies novel γ-globin regulators
      Mullin C, Balbin-Cuesta G, Myers G, Drysdale C, Lin Z, Yu L, McGee B, Friedman A, Khoriaty R. Blood, 2025 Dec 6; 146 (Supplement 1): 1136 - 1136. DOI:10.1182/blood-2025-1136
    • Journal Article
      Novel, potent, and orally bioavailable LSD1 inhibitors induce fetal hemoglobin synthesis in a sickle cell disease mouse model
      Wang Y, Yu L, Deng K, Packiarajan M, Aguilar A, An S, Liu X, Myers G, Oh H, Singh SA, Cho US, Wang S, Guan Y, White AD, Khoriaty R, Engel JD. Blood, 2025 Jul 17; 146 (3): 356 - 368. DOI:10.1182/blood.2024028006
      PMID: 40332031
    • Presentation
      Congenital dyserythropoietic anemia type II: from biology to novel therapeutic strategies
      Khoriaty R. 2025 Oct 9;

    Featured News & Stories

    Department News

    New Publication by the Khoriaty and Engel labs!

    Blood published "The LSD1 Inhibitor RN1 Rescues Congenital Dyserythropoietic Anemia Type II" by the Khoriaty and Engel labs.
    Department News

    New Publication from Claire Drysdale (Khoriaty lab)

    The American Society of Hematology Blood Journal published "The Saga Complex Member TADA2B Is a Novel Regulator of γ-Globin Production" by first author Claire Drysdale (Khoriaty lab).