Rami Khoriaty, MD
Associate Professor of Internal Medicine
Associate Professor of Cell and Developmental Biology
Medical School
Available to mentor
Rami Khoriaty, MD
Associate Professor
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Center Memberships
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Center MemberRogel Cancer Center
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Center MemberCenter for Cell Plasticity and Organ Design
Recent Publications
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Deng K, Wang Y, Min JC, Liu X, Ueharu H, Myers G, Yu L, Hammoud SB, Adam A, Saba R, Natogi V, Drysdale C, Chen B, Yee JL, Kitzman J, Lyssiotis CA, Mishina Y, Jones MA, Kaartinen V, Guan Y, Khoriaty R, Engel JD, Singh SA. Blood Adv, 2026 Jan 23;Journal ArticleLipid Metabolism Transcriptomic Signature of Defective Erythropoiesis in Diamond Blackfan Anemia syndrome.
DOI:10.1182/bloodadvances.2025017318 PMID: 41576344 -
Mullin C, Lin K, Choe E, Sha C, Shukla Z, Campbell K, McCarter AC, Wang A, Nieves-Salva J, Khan S, Keeley TM, Liang S, Wang Q, Melnick AF, Evans P, Monovich AC, Iyer A, Kodgule R, Deng Y, da Veiga Leprevost F, Barnett KR, Pölönen P, Khoriaty R, Savic D, Teachey DT, Mullighan CG, Cieslik M, Nesvizhskii AI, Samuelson LC, Jones M, Li Q, Ryan RJH, Chiang MY. Journal of Clinical Investigation, 2026 Jan 16; 136 (2): 1 - 17.Journal ArticleThe hematopoietic stem cell MYB enhancer is essential for and recurrently amplified during T cell leukemogenesis
DOI:10.1172/JCI189830 -
Mullin C, Lin K, Choe E, Sha C, Shukla Z, Campbell K, McCarter AC, Wang A, Nieves-Salva J, Khan S, Keeley TM, Liang S, Wang Q, Melnick AF, Evans P, Monovich AC, Iyer A, Kodgule R, Deng Y, da Veiga Leprevost F, Barnett KR, Pölönen P, Khoriaty R, Savic D, Teachey DT, Mullighan CG, Cieslik M, Nesvizhskii AI, Samuelson LC, Jones M, Li Q, Ryan RJ, Chiang MY. Journal of Clinical Investigation, 2026 Jan 2; 136 (1):Journal ArticleThe hematopoietic stem cell MYB enhancer is essential for and recurrently amplified during T cell leukemogenesis
DOI:10.1172/JCI187998 PMID: 41129262 -
Balbin-Cuesta G, Drysdale C, Kerpet C, Yu L, Myers G, Lin Z, McGee B, Friedman A, Liu X, Singh SA, Engel JD, Buttitta L, Khoriaty R. Blood, 2026 Jan 1;Journal Articlep27Kip1regulates γ-globin production
DOI:10.1182/blood.2025028895 PMID: 41411145 -
Myers G, Friedman A, Yu L, Pourmandi N, Kerpet C, Ito MA, Saba R, Tang V, Ozel AB, Bergin IL, Johnson CN, Ku CJ, Wang Y, Balbin-Cuesta G, Lim KC, Lin Z, Drysdale C, McGee B, Kurita R, Nakamura Y, Liu X, Siemieniak D, Singh SA, Lyssiotis CA, Maillard I, Weisman LS, Engel JD, Khoriaty R. Nature Communications, 2025 Dec 1; 16 (1):Journal ArticleA genome-wide screen identifies genes required for erythroid differentiation
DOI:10.1038/s41467-025-58739-w PMID: 40221460 -
Mullin C, Balbin-Cuesta G, Myers G, Drysdale C, Lin Z, Yu L, McGee B, Friedman A, Khoriaty R. Blood, 2025 Dec 6; 146 (Supplement 1): 1136 - 1136.Proceeding / Abstract / PosterA genome-wide CRISPR activation screen identifies novel γ-globin regulators
DOI:10.1182/blood-2025-1136 -
Wang Y, Yu L, Deng K, Packiarajan M, Aguilar A, An S, Liu X, Myers G, Oh H, Singh SA, Cho US, Wang S, Guan Y, White AD, Khoriaty R, Engel JD. Blood, 2025 Jul 17; 146 (3): 356 - 368.Journal ArticleNovel, potent, and orally bioavailable LSD1 inhibitors induce fetal hemoglobin synthesis in a sickle cell disease mouse model
DOI:10.1182/blood.2024028006 PMID: 40332031 -
Khoriaty R. 2025 Oct 9;PresentationCongenital dyserythropoietic anemia type II: from biology to novel therapeutic strategies
Featured News & Stories
Department News
New Publication by the Khoriaty and Engel labs!
Blood published "The LSD1 Inhibitor RN1 Rescues Congenital Dyserythropoietic Anemia Type II" by the Khoriaty and Engel labs.
Department News
New Publication from Claire Drysdale (Khoriaty lab)
The American Society of Hematology Blood Journal published "The Saga Complex Member TADA2B Is a Novel Regulator of γ-Globin Production" by first author Claire Drysdale (Khoriaty lab).