Charles S Mayo

 Charles S. Mayo
Clinical Professor of Radiation Oncology
Medical School
University of Michigan–Ann Arbor
Radiation Oncology - Physics
1500 East Medical Center Drive
Ann Arbor, MI 48103-5010
[email protected]
Available to mentor
Charles S Mayo
Charles S. Mayo
Clinical Professor
  • About
  • Center Memberships
  • Research Overview
  • Recent Publications

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    • About

    Dr. Mayo has over 35 years’ experience in clinical medical physics and translational research, He is an internationally recognized expert in health care informatics (infrastructure, standardizations, and analysis), application of statistical methods in treatment and outcomes modeling, automation of advanced treatment planning methods and reirradiation.

    Center Memberships
    • Center Member
      AI and Digital Health Innovation
    • Center Member
      Institute for Healthcare Policy and Innovation

    Research Overview

    Areas of Interest:
    - Development of analytics metrics and visualizations distilled from big data resources to improve practice and outcomes.
    - Development of professional society based, standardizations and linked software applications supporting automation in use of large scale, comprehensive real world learning health systems (LSRW-LHS) to create AI ready data structures.
    - Federated Learning Networks based on Operational Ontology for Oncology (O3) standardizations
    - Automated Statistical Profiling and AI methods for evidence driven discovery with LSRW-LHS

    Clinical Interests:
    - Advanced and automated treatment planning methods and assesment tools
    - SRS and SBRT
    - Intravascular brachy therapy
    - Reirradation

    Recent Publications

     See All Publications
    • Journal Article
      Order From Chaos: The Benefits of Standardized Nomenclature in Radiation Oncology
      Richardson SL, Bosch WR, Mayo CS, McNutt TR, Moran JM, Popple RA, Xiao Y, Covington EL. Practical Radiation Oncology, 2024 Nov 1; 14 (6): 582 - 589. DOI:10.1016/j.prro.2024.04.002
      PMID: 38636586
    • Journal Article
      Predictive Factors Associated With Radiation Myelopathy in Pediatric Patients With Cancer: A PENTEC Comprehensive Review
      Cooper BT, Mayo CS, Milano MT, Olch AJ, Oh C, Keating GF, Hallstrom A, Constine LS, Laack NN. International Journal of Radiation Oncology Biology Physics, 2024 Jun 1; 119 (2): 494 - 506. DOI:10.1016/j.ijrobp.2023.12.020
      PMID: 38323945
    • Journal Article
      2851: Operational Ontology for Oncology (O3) - Multi-professional society standard supporting AI
      Mayo CS, Feng MU, Brock KK, Kudner R, Balter P, Buchsbaum J, Caissie A, Daugherty E, Dekker A, Fuller CD, Hong J, Hong D, Kamran S, Katsoulakis E, Kildea J, Krauze A, Kruse J, McNutt T, Mierzwa M, Moreno A, Palta J, Popple R, Purdie T, Yom S, Ying X. Radiotherapy and Oncology, 2024 Sep 1; 194: s2977 - s2979. DOI:10.1016/s0167-8140(24)02984-0
    • Journal Article
      Operational Ontology for Oncology (O3): A Professional Society-Based, Multistakeholder, Consensus-Driven Informatics Standard Supporting Clinical and Research Use of Real-World Data From Patients Treated for Cancer
      Mayo CS, Feng MU, Brock KK, Kudner R, Balter P, Buchsbaum JC, Caissie A, Covington E, Daugherty EC, Dekker AL, Fuller CD, Hallstrom AL, Hong DS, Hong JC, Kamran SC, Katsoulakis E, Kildea J, Krauze AV, Kruse JJ, McNutt T, Mierzwa M, Moreno A, Palta JR, Popple R, Purdie TG, Richardson S, Sharp GC, Satomi S, Tarbox LR, Venkatesan AM, Witztum A, Woods KE, Yao Y, Farahani K, Aneja S, Gabriel PE, Hadjiiski L, Ruan D, Siewerdsen JH, Bratt S, Casagni M, Chen S, Christodouleas JC, DiDonato A, Hayman J, Kapoor R, Kravitz S, Sebastian S, Von Siebenthal M, Bosch W, Hurkmans C, Yom SS, Xiao Y. International Journal of Radiation Oncology Biology Physics, 2023 Nov 1; 117 (3): 533 - 550. DOI:10.1016/j.ijrobp.2023.05.033
      PMID: 37244628
    • Journal Article
      Machine Learning Model of Emergency Department Use for Patients Undergoing Treatment for Head and Neck Cancer Using Comprehensive Multifactor Electronic Health Records
      Mayo CS, Mierzwa M, Yalamanchi P, Evans J, Worden F, Medlin R, Schipper M, Schonewolf C, Shah J, Spector M, Swiecicki P, Mayo K, Casper K. JCO clinical cancer informatics, 2023 Jul 2; 7: e2200037 - e2200037. DOI:10.1200/CCI.22.00037
    • Journal Article
      Development and Clinical Implementation of an Automated Virtual Integrative Planner for Radiation Therapy of Head and Neck Cancer.
      Jaworski EM, Mierzwa ML, Vineberg KA, Yao J, Shah JL, Schonewolf CA, Litzenberg D, Gharzai LA, Matuszak MM, Paradis K, Dougherty A, Burger P, Tatro D, Arnould GS, Moran JM, Lee C, Eisbruch A, Mayo CS. Advances in Radiation Oncology, 2022 Jul; DOI:10.1016/j.adro.2022.101029
    • Journal Article
      Canadian Partnership for Quality Radiotherapy : Guidance on the Use of Common Nomenclature in Canadian Radiation Treatment Programs
      Kildea J, Brown E, Caissie A, Letourneau E, Mayo C, Millette M-P, Milosevic M, Nielsen M, Popovic M, Purdie TG, Rans K, Stevens T. http://www.cpqr.ca/wp-content/uploads/2021/04/UCN.2021.03.01.pdf, 2021 Mar 31; http://www.cpqr.ca/wp-content/up:
    • Journal Article
      Radiotherapy (RT) Patterns Of Practice Variability Identified As A Challenge To Real-World Big Data: Recommendations From The Learning From Analysis Of Multicenter Big Data Aggregation (LAMBDA) Consortium
      Caissie AL, Mierzwa ML, Fuller CD, Rajaraman M, Lin A, McDonald AM, Popple RA, Xiao Y, van Dijk L, Balter P, Fong H, Ping H, Kovoor M, Lee J, Rao A, Martel MK, Thompson RF, Merz B, Yao J, Mayo C. International Journal of Radiation Oncology • Biology • Physics, 2020 Oct 29; 108 (3): e773 - e774. DOI:10.1016/j.ijrobp.2020.07.224