Andrew D Schrepf, PhD
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About
Dr. Schrepf is an Assistant Professor of Anesthesiology in the University of Michigan Chronic Pain and Fatigue Research Center (CPFRC) and an Assistant Professor of Obstetrics & Gynecology at Michigan Medicine. He completed his undergraduate work at Cornell College and his doctorate in Psychology at the University of Iowa. His work focuses on the way the immune system influences the central nervous system in chronic pain, using dynamic blood-based markers of immune activity in conjunction with MRI. He is a long-time member of the Biomarker working group in the NIDDK-funded MAPP research network, and a Co-Chair of the Biospecimens working group for the NIAMS-funded BACPAC research collaborative as well as several other HEAL initiative projects.
Qualifications
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Research FellowUniversity of Michigan–Ann Arbor, Ann Arbor, United States
2015 - 2017
Postdoctoral Research
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PhD, Health PsychologyUniversity of Iowa, Iowa City, IA, United States
2010 - 2015
Center Memberships
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Center MemberCaswell Diabetes Institute
Research Overview
• Inflammatory biology of complex medical symptoms
• Post-treatment symptom trajectories in chronic pain
• Immune system influence on the central nervous system
• Quantitative sensory testing in chronic pain
Recent Publications
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Neumann A, Longo J, De EJB, Schrepf A, Kelly AG, McKernan LC. Current Bladder Dysfunction Reports, 2026 Dec 1; 21 (1):Journal ArticlePsychological and Behavioral Contributors to Lower Urinary Tract Dysfunction: Trauma, Stress, and Neurobiological Pathways
DOI:10.1007/s11884-026-00824-x -
Hidalgo-Lopez E, Portengen CM, Smith T, Angstadt M, Schrepf A, Clauw DJ, Harte SE, Heitzeg MM, Mindell JA, Beltz AM, Kaplan CM. Communications Biology, 2026 Jul 23;Journal ArticleSex-specific developmental pathways link brain networks, sensory sensitivity, and sleep to adolescent pain
DOI:10.1038/s42003-026-10619-9 -
Stefanov K, Parkinson JT, Sunzini F, Al-Wasity S, Kaplan CM, Schrepf A, Ichesco E, Porter DA, Keith GA, McGucken A, Brock J, Aldehmi N, Paramo-Fiscal L, Tulunay-Virlan A, Arnott M, Lau T, Goodyear C, Thut G, Shenker N, McInnes IB, Clauw DJ, Cavangh J, Basu N. 2026 Jul 16; medRxiv,PreprintJAK-STAT pathway inhibition modulates centrally sensitised default mode network hubs in rheumatoid arthritis pain
DOI:10.64898/2026.07.12.26356929 -
Cherin J, McLain N, Schrepf A, Rodriguez LV, Kutch JJ. Pain Rep, 2026 Jun; 11 (3): e1436Journal ArticleAssociation of widespread pain and peak alpha frequency cannot be isolated to a single network.
DOI:10.1097/PR9.0000000000001436 PMID: PMC13068460 -
Waller N, Harte SE, Harris RE, Schrepf A, Smith T, Ichesco E, Kaplan C, Sunzini F, Minhas D, Marder W, Till SR, Williams DA, Brummett CM, Basu N, As-Sanie S, Clauw DJ. Arthritis Rheumatol, 2026 Jun; 78 (6): 1339 - 1349.Journal ArticleVisual Hypersensitivity as a Transdiagnostic Marker of Surgical Pain Response in Arthritis and Chronic Pain Syndromes.
DOI:10.1002/art.70042 PMID: PMC12910465 -
Schrepf A, Smith T, Waller N, Harris RE, Ichesco E, Kaplan CM, Till SR, Williams DA, As-Sanie S, Evanski JM, Urquhart A, Brummett CM, Clauw DJ, Harte SE. 2026 May 27; openRxiv,PreprintGeneralized Sensory Sensitivity for Prediction of Post-Surgical Analgesic Outcomes: An Observational Cohort Study of Total Hip Arthroplasty and Hysterectomy
DOI:10.64898/2026.05.26.26354108 -
Hidalgo-Lopez E, Portengen C, Smith T, Becker HC, Schrepf A, Harte SE, Beltz AM, Kaplan CM. Biol Sex Differ, 2026 Apr 6;Journal ArticleCortical thickness, surface area, and multisite pain: distinct patterns by sex in adolescence.
DOI:10.1186/s13293-026-00898-6 PMID: 41943162 -
2026 Jul 11;PresentationThe Chicken or the Ache? Untangling the Relationship of Multisensory Sensitivity and Chronic Pain
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