Thomas H SIsson, MD

Thomas sisson
Clinical Professor of Internal Medicine
Clerkship Director and Associate Director
Physician Scientist Training Program and Fellows
Internal Medicine
Medical School
[email protected]
Available to mentor
Thomas H SIsson, MD
Thomas sisson
Clinical Professor
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  • Recent Publications

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    • Journal Article
      A potent inhibitor of PAI-1, MDI-2517, mitigates disease severity in a preclinical systemic sclerosis model
      Su EJ, Tsou PS, Warnock M, Subbotina N, Mann K, Vichaikul S, Rosek A, Leung L, Xing X, Xing E, Plazyo O, Bogle R, Tsoi LC, Emal CD, Khanna D, Varga J, Sisson TH, Gudjonsson JE, Lawrence DA. Jci Insight, 2026 Apr 8; 11 (7): DOI:10.1172/jci.insight.195005
      PMID: 41701900
    • Journal Article
      SORL1 is a receptor for tau that promotes tau seeding
      Cooper JM, Lathuiliere A, Su EJ, Song Y, Torrente D, Jo Y, Weinrich N, Sales JD, Migliorini M, Sisson TH, Lawrence DA, Hyman BT, Strickland DK. Journal of Biological Chemistry, 2024 Jun 1; 300 (6): DOI:10.1016/j.jbc.2024.107313
      PMID: 38657864
    • Journal Article
      CD36/Lyn kinase interactions within macrophages promotes pulmonary fibrosis in response to oxidized phospholipid
      Kwak D, Bradley PB, Subbotina N, Ling S, Teitz-Tennenbaum S, Osterholzer JJ, Sisson TH, Kim KK. Respiratory Research, 2023 Dec 1; 24 (1): DOI:10.1186/s12931-023-02629-6
      PMID: 38098035
    • Presentation
      "Sustained Club Cell Injury Induces Histopathologic Features of Deployment-Related Constrictive Bronchiolitis"
      2022 Feb 1;
    • Journal Article
      Defibrotide therapy for SARS-CoV2 Acute Respiratory Distress Syndrome (ARDS).
      Frame D, Scappaticci GB, Braun TM, Maliarik M, Sisson TH, Pipe SW, Lawrence DA, Richardson PG, Holinstat M, Hyzy RC, Kaul DR, Gregg KS, Lama VN, Yanik GA. Chest, 2022 Aug 6;
    • Proceeding / Abstract / Poster
      Defibrotide therapy for SARS-CoV2 Acute Respiratory Distress Syndrome (ARDS).
      Frame D, Scappaticci GB, Braun TM, Maliarik M, Sisson TH, Pipe SW, Lawrence DA, Richardson PG, Holinstat M, Hyzy RC, Kaul DR, Gregg KS, Lama VN, Yanik GA. Chest, 2022 Aug 6;
    • Proceeding / Abstract / Poster
      Depletion of Alveolar Macrophages Ameliorates Club Cell Injury-Induced Peribronchiolar Fibrosis in a Murine Model of Deployment-Related Constrictive Bronchiolitis
      Osterholzer JJ, Teitz-Tennenbaum S, Selbmann KN, Lahiri S, Subbotina N, Sisson TH, Perl AK-T. Am J Respir Crit Care Med, 2022 Jan 1;
    • Journal Article
      Diverse injury pathways induce alveolar epithelial cell CCL2/12 which promotes lung fibrosis
      Yang J, Agarwal M, Ling S, Teitz-Tennenbaum S, Zemans RL, Osterholzer JJ, Sisson TH, Kim KK. Am J Resp Cell and Mol Biol, 2020 May 1; 62 (5): 622 - 632.