Thomas H SIsson, MD
Clinical Professor of Internal Medicine
Clerkship Director and Associate Director
Physician Scientist Training Program and Fellows
Internal Medicine
Medical School
[email protected]
Available to mentor
Thomas H SIsson, MD
Clinical Professor
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Recent Publications
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Su EJ, Tsou PS, Warnock M, Subbotina N, Mann K, Vichaikul S, Rosek A, Leung L, Xing X, Xing E, Plazyo O, Bogle R, Tsoi LC, Emal CD, Khanna D, Varga J, Sisson TH, Gudjonsson JE, Lawrence DA. Jci Insight, 2026 Apr 8; 11 (7):Journal ArticleA potent inhibitor of PAI-1, MDI-2517, mitigates disease severity in a preclinical systemic sclerosis model
DOI:10.1172/jci.insight.195005 PMID: 41701900 -
Cooper JM, Lathuiliere A, Su EJ, Song Y, Torrente D, Jo Y, Weinrich N, Sales JD, Migliorini M, Sisson TH, Lawrence DA, Hyman BT, Strickland DK. Journal of Biological Chemistry, 2024 Jun 1; 300 (6):Journal ArticleSORL1 is a receptor for tau that promotes tau seeding
DOI:10.1016/j.jbc.2024.107313 PMID: 38657864 -
Kwak D, Bradley PB, Subbotina N, Ling S, Teitz-Tennenbaum S, Osterholzer JJ, Sisson TH, Kim KK. Respiratory Research, 2023 Dec 1; 24 (1):Journal ArticleCD36/Lyn kinase interactions within macrophages promotes pulmonary fibrosis in response to oxidized phospholipid
DOI:10.1186/s12931-023-02629-6 PMID: 38098035 -
2022 Feb 1;Presentation"Sustained Club Cell Injury Induces Histopathologic Features of Deployment-Related Constrictive Bronchiolitis"
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Frame D, Scappaticci GB, Braun TM, Maliarik M, Sisson TH, Pipe SW, Lawrence DA, Richardson PG, Holinstat M, Hyzy RC, Kaul DR, Gregg KS, Lama VN, Yanik GA. Chest, 2022 Aug 6;Journal ArticleDefibrotide therapy for SARS-CoV2 Acute Respiratory Distress Syndrome (ARDS).
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Frame D, Scappaticci GB, Braun TM, Maliarik M, Sisson TH, Pipe SW, Lawrence DA, Richardson PG, Holinstat M, Hyzy RC, Kaul DR, Gregg KS, Lama VN, Yanik GA. Chest, 2022 Aug 6;Proceeding / Abstract / PosterDefibrotide therapy for SARS-CoV2 Acute Respiratory Distress Syndrome (ARDS).
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Osterholzer JJ, Teitz-Tennenbaum S, Selbmann KN, Lahiri S, Subbotina N, Sisson TH, Perl AK-T. Am J Respir Crit Care Med, 2022 Jan 1;Proceeding / Abstract / PosterDepletion of Alveolar Macrophages Ameliorates Club Cell Injury-Induced Peribronchiolar Fibrosis in a Murine Model of Deployment-Related Constrictive Bronchiolitis
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Yang J, Agarwal M, Ling S, Teitz-Tennenbaum S, Zemans RL, Osterholzer JJ, Sisson TH, Kim KK. Am J Resp Cell and Mol Biol, 2020 May 1; 62 (5): 622 - 632.Journal ArticleDiverse injury pathways induce alveolar epithelial cell CCL2/12 which promotes lung fibrosis