Maureen Sartor, PhD
Co-Director
Bioinformatics Graduate Program
Professor of Computational Medicine and Bioinformatics
Professor of Biostatistics
[email protected]

Available to mentor

Maureen Sartor, PhD
Professor
  • Center Memberships
  • Research Overview
  • Links
  • Recent Publications
  • Center Memberships
    • Center Member
      Rogel Cancer Center
    • Center Member
      Precision Health Initiative
    Research Overview

    The Sartor laboratory has both methodological and biomedical areas of focus. Their methodological focus is bioinformatics methods and tools for the analysis of genome-wide regulatory and epigenomics data, and for assessing the biological/clinical significance of results. For instance, Dr. Sartor is a member of the Impact of Genomic Variants on Function (IGVF) NIH Consortium, for which she is developing a coupled tensor-matrix completion method to prioritize disease-specific variant-gene target pairs. The Sartor Lab also focuses on multi-omics approaches for biomarker and treatment-target discovery in disease, focusing specifically on Amyotrophic Lateral Sclerosis (ALS) and head and neck squamous cell carcinomas (HNSCC). Dr. Sartor is PI of an R01 studying downstream consequences of HPV integration in HPV-associated HNSCC, and Co-PI of a Transformative R01 linking environmental exposures with multi-omics in ALS. Being formally trained in biostatistics, Dr. Sartor uses machine learning and statistical approaches to make advances in the above areas.

    Links
    • Sartor Lab
    Recent Publications See All Publications
    • Journal Article
      Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver: A Focus on Genomic Imprinting by Tissue and Sex.
      Morgan RK, Wang K, Svoboda LK, Rygiel CA, Lalancette C, Cavalcante R, Bartolomei MS, Prasasya R, Neier K, Perera BPU, Jones TR, Colacino JA, Sartor MA, Dolinoy DC. Environ Health Perspect, 2024 Jun; 132 (6): 67003 DOI:10.1289/EHP14074
      PMID: 38833407
    • Journal Article
      Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations.
      Kandarpa M, Robinson D, Wu Y-M, Qin T, Pettit K, Li Q, Luker G, Sartor M, Chinnaiyan A, Talpaz M. Clin Cancer Res, 2024 May 1; 30 (9): 1972 - 1983. DOI:10.1158/1078-0432.CCR-23-0372
      PMID: 38386293
    • Additional Scholarship
      Data from Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations
      Kandarpa M, Robinson D, Wu Y-M, Qin T, Pettit K, Li Q, Luker G, Sartor M, Chinnaiyan A, Talpaz M. 2024 May 1; DOI:10.1158/1078-0432.c.7209134.v1
    • Additional Scholarship
      Data from Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations
      Kandarpa M, Robinson D, Wu Y-M, Qin T, Pettit K, Li Q, Luker G, Sartor M, Chinnaiyan A, Talpaz M. 2024 May 1; DOI:10.1158/1078-0432.c.7209134
    • Additional Scholarship
      Supplemental Figure 1 from Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations
      Kandarpa M, Robinson D, Wu Y-M, Qin T, Pettit K, Li Q, Luker G, Sartor M, Chinnaiyan A, Talpaz M. 2024 May 1; DOI:10.1158/1078-0432.25728728.v1
    • Additional Scholarship
      Supplemental Figure 1 from Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations
      Kandarpa M, Robinson D, Wu Y-M, Qin T, Pettit K, Li Q, Luker G, Sartor M, Chinnaiyan A, Talpaz M. 2024 May 1; DOI:10.1158/1078-0432.25728728
    • Additional Scholarship
      Supplemental Figure 2 from Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations
      Kandarpa M, Robinson D, Wu Y-M, Qin T, Pettit K, Li Q, Luker G, Sartor M, Chinnaiyan A, Talpaz M. 2024 May 1; DOI:10.1158/1078-0432.25728725
    • Additional Scholarship
      Supplemental Figure 2 from Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations
      Kandarpa M, Robinson D, Wu Y-M, Qin T, Pettit K, Li Q, Luker G, Sartor M, Chinnaiyan A, Talpaz M. 2024 May 1; DOI:10.1158/1078-0432.25728725.v1
    Featured News & Stories
    Department News
    Congratulations to Dr. Kai Wang for your K99/R00 grant
    Congratulations to Dr. Kai Wang, who was awarded a K99/R00 grant starting August 2023 from the NIEHS titled “Improving chemical exposome target prediction by application of Coupled Matrix/Tensor-Matrix Completion algorithms.”