Oren Sagher

Oren Sagher
Professor
Office:
University of Michigan
Department of Neurosurgery
1500 E. Medical Center Drive, TC3552
Ann Arbor, MI 48109
Email:
[email protected]
Phone:
Available to mentor
Oren Sagher
Oren Sagher
Professor
  • About
  • Qualifications
  • Research Overview
  • Recent Publications
  • Manage Your Profile

  • About

    Dr. Oren Sagher is the William F. Chandler Collegiate Professor of Neurosurgery at the University of Michigan. He has been on faculty at the University since 1993, and is currently Associate Chair for Technological Innovations and Residency Program Director. In the latter role, he is responsible for running a busy neurosurgery residency training program, and mentoring numerous residents, fellows and students. His main clinical interest is in the domain of functional neurosurgery, encompassing the treatment of epilepsy, movement disorders and pain. He serves as the lead epilepsy surgeon at Michigan Medicine, and is interested in brain mapping and advanced imaging techniques in the operating room. Outside the university, Dr. Sagher has held leadership positions in national neurosurgical organizations, with a strong interest in neurosurgical education.

    In addition to his work as an academic neurosurgeon, Dr. Sagher also has a strong interest in health-related information technology. In that vein, he created an online neurosurgical portal in 1999, and has continued to develop this platform over the years to a point where it currently informs and drives the care of all neurosurgical patients at the University of Michigan, supplying all providers within the department with timely information needed to optimize the care of their patients. This information system has been extended for use in other services, such as Radiation Oncology and Stroke Neurology.

    Qualifications

    • Residency
      University of Virginia, Department of Neurosurgery, United States
      1988 - 1993
      Residency
    • Research Fellow
      University of Virginia, Charlottesville, United States
      1992 - 1993
      Postdoctoral Research
    • Internship
      University of Virginia, Department of Surgery, United States
      1987 - 1988
      Internship
    • MD
      1987

    Research Overview

    Dr. Sagher has a long-standing interest in the regulation of cerebral blood flow, particularly as it relates to neurostimulation. He has led an R01-funded research effort into cerebral blood flow regulation, stroke, and electrical neurostimulation. In addition, he has had an interest in brain tumor imaging, and has been funded by an NIH Quantum grant to study the use of targeted nanoparticles to image brain tumors within the operating room.

    Recent Publications

    See All Publications
    • Journal Article
      Predicting postoperative hospice enrollment following stereotactic brain biopsy: a retrospective study and risk score development
      Tripathy A, Harake ES, Ahmad A, Sharba N, Li A, Saleh S, Sagher O, Heth JA, Altshuler D, Hollon TC, Thompson BG, Pandey AS, Umemura Y, Al-Holou WN. Journal of Neurosurgery, 2026 Oct 1; 145 (4): 1161 - 1173. DOI:10.3171/2026.2.JNS251994
      PMID: 42537242
    • Journal Article
      The Scarlet Letter of the Unmatched Neurosurgery Reapplicant: Trends, Opinions, and Guidance from a Nationwide Survey
      Cole KL, Van Gompel J, Sagher O, Pham M, Cook S, Cole CD, Spinner RJ, Murad GJ, Couldwell WT, Jensen RL. Journal of the American College of Surgeons, 2026 Jun 1; 242 (6): 1517 - 1528. DOI:10.1097/XCS.0000000000001737
      PMID: 41404973
    • Journal Article
      Minimizing the risks of stereotactic brain biopsy in suspected central nervous system lymphoma: a retrospective database study
      Li A, Saleh S, Sharba N, Guivatchian E, Sagher O, Sullivan SE, Heth JA, Hollon TC, Thompson BG, Pandey AS, Umemura Y, Al-Holou WN. Journal of Cancer Research and Clinical Oncology, 2026 Mar 1; 152 (3): DOI:10.1007/s00432-026-06458-0
      PMID: 41886097
    • Presentation
      "Neuro-Ophthalmology Grand Rounds" (Grand Rounds; residency interview day)
      Deveney T, Wilseck Z, Trobe J, Sagher O. 2026 Feb 23;
    • Journal Article
      Changes in anxiety after temporal lobe epilepsy surgery: A systematic review and meta-analysis
      Rashidi F, Maleki S, Sabahi M, Habibi MA, Naseri Alavi SA, Arfaie S, Flouty O, Warnke P, Sagher O, Adada B. Epilepsy and Behavior, 2025 Mar 1; 164: DOI:10.1016/j.yebeh.2025.110296
      PMID: 39923724
    • Journal Article
      Metabolomic Profiles of Human Glioma Inform Patient Survival
      Scott AJ, Correa LO, Edwards DM, Sun Y, Ravikumar V, Andren AC, Zhang L, Srinivasan S, Jairath N, Verbal K, Muraszko K, Sagher O, Carty SA, Hervey-Jumper S, Orringer D, Kim MM, Junck L, Umemura Y, Leung D, Venneti S, Camelo-Piragua S, Lawrence TS, Ippolito JE, Al-Holou WN, Chinnaiyan P, Heth J, Rao A, Lyssiotis CA, Wahl DR. Antioxidants and Redox Signaling, 2023 Nov 1; 39 (13-15): 942 - 956. DOI:10.1089/ars.2022.0085
      PMID: 36852494
    • Journal Article
      Identification of Excellent Prognosis IDH Wildtype Glioblastomas Using Genomic and Metabolic Profiling
      Edwards DM, Hopkins A, Scott A, Mannan R, Cao X, Zhang L, Andren A, Heth JA, Muraszko K, Sagher O, Orringer D, Hollon T, Hervey-Jumper S, Venneti S, Camelo-Piragua S, Al-Holou W, Chinnaiyan A, Lyssiotis CA, Wahl DR. International Journal of Radiation Oncology*Biology*Physics, 2024 Aug 9; 117 (2): e101 - e101. DOI:10.1016/j.ijrobp.2023.06.870
    • Proceeding / Abstract / Poster
      Identification of Excellent Prognosis IDH Wildtype Glioblastomas Using Genomic and Metabolomic Profiling.
      Edwards D, Hopkins A, Scott A, Mannan R, Cao X, Zhang L, Anhren A, Heth J, Muraszko K, Sagher O, Orringer D, Hollon T, Hervey-Jumper S, Venneti S, Camelo-Piragua S, Al-Holou W, Chinnaiyan A, Lyssiotis C, Wahl D. 2023 Oct 12;

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