Ann Arbor
MI, 48109 United States
Available to mentor
I am the Medical Director of Lung Transplantation at UM. I oversee all clinical, programmatic, and educational components of the Lung Transplantation Program. I am involved in translational and outcomes research, including NIH-funded multicenter studies. In addition, I am site PI of a clinical trial to study the role of a novel drug in preventing transplant rejection. I have developed curricula for students, residents, fellows, junior attendings, and non-physician learners in the clinical management of pre- and post-lung transplant patients. I chair several monthly interdisciplinary meetings to integrate my program with the great UM Transplant Center including a meeting to select and list transplant candidates, and morbidity and mortality and QI meetings. Based on my international reputation as an expert in the field, I have been invited to serve on multiple committees of the United Network for Organ Sharing (UNOS), which oversees lung transplantation throughout the United States. My role on these committees included developing and approving a new allocation system for prioritization and waitlist rank and lung allocation to reduce deaths on the waitlist, improve access, and mitigate tissue injury.
From 2019-2021, I served as MPLAN Medical Director of the 8D Medical Surgical Intermediate respiratory unit, During this period, my role ballooned rapidly expanded to include co-managing (with other unit Medical Directors, ACCO, AOD, ACNO, and CMO) the staffing, bed management, and conversion of 6 units to medical ICUs to house up to 250 COVID patients.
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Lyu D. 2024 Jun 1;PresentationLung Transplant and the Kidney Transplant Safety Net
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Combs MP, Walter K, Hixson H, Belloli EA, Chan KM, Chang AC, Lyu DM. The Journal of Heart and Lung Transplantation, 2024 Apr; 43 (4): s297 - s298.Proceeding / Abstract / PosterEvaluation of Use of Tacrolimus vs. Cyclosporine on CLAD Incidence and Allograft Survival in the ISHLT Registry
DOI:10.1016/j.healun.2024.02.427 -
Combs MP, Walter K, Hixson H, Belloli EA, Najor MS, Chan KM, Chang AC, Lyu DM. J Heart Lung Transplant, 2024 Oct 20;Journal ArticleImpact of tacrolimus vs cyclosporine on chronic lung allograft dysfunction incidence and allograft survival in the International Society of Heart and Lung Transplantation registry.
DOI:10.1016/j.healun.2024.10.013 PMID: 39437867 -
Elsolh B, Bayat Z, Lyu D, Lin J, Wakeam E. J Heart Lung Transplant, 2023 Oct; 42 (10): 1425 - 1436.Journal ArticleLung transplantation for lung cancer: A systematic review of the literature.
DOI:10.1016/j.healun.2023.05.011 PMID: 37253398 -
2023 Aug 4;PresentationThe Composite Allocation Score (CAS) and Lung Transplant
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Bonner SN, Thumma JR, Valbuena VSM, Stewart JW, Combs M, Lyu D, Chang A, Lin J, Wakeam E. J Heart Lung Transplant, 2023 Jul; 42 (7): 985 - 992.Journal ArticleThe intersection of race and ethnicity, gender, and primary diagnosis on lung transplantation outcomes.
DOI:10.1016/j.healun.2023.02.1496 PMID: 36967318 -
OPTN Lung Transplantation Committee . 2023 Mar 9;Additional ScholarshipUNOS Policy: Establish Continuous Distribution of Lungs
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Aoki Y, Walker NM, Misumi K, Mimura T, Vittal R, McLinden AP, Fitzgerald L, Combs MP, Lyu D, Osterholzer JJ, Pinsky DJ, Lama VN. J Heart Lung Transplant, 2023 Mar; 42 (3): 317 - 326.Journal ArticleThe mitigating effect of exogenous carbon monoxide on chronic allograft rejection and fibrosis post-lung transplantation.
DOI:10.1016/j.healun.2022.11.005 PMID: 36522238