Paul W Harms

 Paul W. Harms
Clinical Professor of Pathology and Clinical Professor of Dermatology
Medical School
Email:
[email protected]
Available to mentor
Paul W Harms
Paul W. Harms
Clinical Professor
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  • Research Overview
  • Recent Publications

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    • About

    Dr. Paul Harms is a board-certified pathologist and dermatopathologist.

    Center Memberships
    • Center Member
      Rogel Cancer Center

    Research Overview

    Dr. Harms has interested in molecular markers and mechanisms of cutaneous diseases, especially cutaneous neoplasia. His work has advanced understanding of the genomic drivers of multiple skin malignancies, especially Merkel cell carcinoma.

    Recent Publications

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    • Journal Article
      Dynamic neutrophil-keratinocyte communication network centered on IL-36/TNFSF15 responses characterizes inflammatory responses in generalized pustular psoriasis
      Jiang R, Kirma J, Fox J, Xing X, Wang J, Sarkar MK, Bogle R, Do T, Coon A, Cole C, Plazyo O, Rew JE, Zhang H, Kahlenberg JM, Billi AC, Bachelez H, Tsoi LC, Harms PW, Shao S, Chen X, Gudjonsson JE. Nature Communications, 2026 Dec 1; 17 (1): DOI:10.1038/s41467-025-67917-9
      PMID: 41436466
    • Journal Article
      Single-cell and spatial profiling reveal cDC2A-CXCL13+CD8+ T-epithelial cell crosstalk and cytotoxicity through TNFRSF9 in cutaneous and mucosal lichen planus
      Jiang R, Bogle R, Xing X, Kirma J, Fox J, Harms PW, Do T, Billi AC, Kahlenberg JM, Modlin RL, Teles R, West J, Mangold A, Zhang H, Schneider MA, Bruno S, Roediger B, Martiny-Baron G, Tsoi LC, Hacini-Rachinel F, Röhn TA, Gudjonsson JE. Nature Communications, 2026 Dec 1; 17 (1): DOI:10.1038/s41467-026-70506-z
      PMID: 41832141
    • Journal Article
      0024 Single-cell and spatial analyses identify a TNFSF14-driven S100A8high monocyte–Th17–keratinocyte axis in early hidradenitis suppurativa
      Jiang R, Bogle R, Xing X, Chen L, Fox J, Harms PW, Nakamura M, Fonquerna S, Kahlenberg M, Tsoi LC, Uluckan O, Gudjonsson JE. Journal of Investigative Dermatology, 2026 Jul 22; 146 (8): s4 DOI:10.1016/j.jid.2026.06.055
    • Proceeding / Abstract / Poster
      0038 Early immune circuits in guttate psoriasis reveal pathways governing disease resolution and progression
      Chen L, Jiang R, Bogle R, Kirma J, Fox J, Billi A, Zhang L, Kahlenberg M, Harms PW, Shao S, Tsoi LC, Gudjonsson JE. Journal of Investigative Dermatology, 2026 Jul 23; 146 (8): s7 DOI:10.1016/j.jid.2026.06.069
    • Journal Article
      0918 Genetically anchored single-cell and spatial transcriptomics define pathologic programs in excessive scarring
      Vahidnezhad H, Safari P, Dey P, Harms PW, Tsoi LC, Hakonarson H, Gudjonsson JE. Journal of Investigative Dermatology, 2026 Jul 22; 146 (8): s158 DOI:10.1016/j.jid.2026.06.949
    • Journal Article
      0967 Darier disease patient tissue mirrors in vitro junctional and redox signatures
      McCarthy E, Harmon R, Godsel L, Barak EC, Dodiuk-Gad R, Harms PW, Gudjonsson JE, Paller A, Dahl R, Green K. Journal of Investigative Dermatology, 2026 Jul 22; 146 (8): s167 DOI:10.1016/j.jid.2026.06.998
    • Preprint
      An immunocompetent Merkel cell carcinoma model for preclinical studies
      Verhaegen ME, Bhatia S, Singer KL, Baumbick M, Huang P-W, Syu L-J, Wilbert D, Selig A, Farjo GA, Walter E, Wolinski N, Furgal A, Galloway DA, Harms PW, Cieslik M, Dlugosz AA. 2026 Jun 28; bioRxiv, DOI:10.64898/2026.06.25.734228
    • Preprint
      Multiomic Analysis Reveals an IFN-driven Cellular Landscape Effectively Targeted by Ruxolitinib in Hailey-Hailey Disease.
      Ceccacci S, Minh Pham HD, Dessaignes M, Mirzayan J, Roger K, Tsoi LC, Harms PW, Gudjonsson JE, Puig Lombardi ME, Guerrera IC, Hovnanian A. 2026 Jun 4; DOI:10.64898/2026.06.01.729262
      PMID: 42282850