Scott Schuetze, MD, PhD
Internal Medicine - Hematology/Oncology
1500 E. Medical Center Drive
Ann Arbor, MI 48109
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About
Dr. Schuetze is a medical oncologist and clinical researcher who has been caring for patients with connective tissue tumors including soft tissue and bone sarcomas for over 25 years. He has over 25 years of experience in oversight and conduct of translational and therapeutic trials in patients with bone and soft tissue sarcomas and benign connective tissue tumors. He has been Principal Investigator of NCTN and ETCTN supported clinical trials. He has served as the Medical Director of the Rogel Cancer Center Oncology-Clinical Trials Support Unit since 2010 and is the co-leader of the Connective Tissue Clinical Research Team. He was awarded an ASCO Advanced Clinical Research Award in Sarcoma in 2008, the University of Michigan Division of Hematology/Oncology Excellence in Research Award in 2010, and an NIH Cancer Clinical Investigator Team Leadership Award in 2012. He currently serves as the contact Principal Investigator for the multi-institutional LMS SPORE “The Genetics and Genomics of Leiomyosarcoma: Improved understanding of cancer biology and new approaches to diagnosis and treatment”, and the Clinical Cancer Prevention grant from the Division of Cancer Prevention in the NCI.
Qualifications
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FellowFred Hutchinson/University of Washington Cancer Consortium, Seattle, United States
1996 - 1999
Clinical Fellowship
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ResidentDuke University Health System, Durham, United States
1993 - 1996
Residency
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MD, PhDOregon Health Sciences University School of Medicine, Portland, Oregon, United States
1986 - 1993
Center Memberships
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Center MemberRogel Cancer Center
Research Overview
Evaluation of experimental therapeutic drugs in the treatment of patients with connective tissue tumors and sarcomas. Evaluation of imaging and blood-based biomarkers in patients with connective tissue tumors and sarcomas. Evaluation of molecular pathogenesis of connective tissue tumors and sarcomas.
Recent Publications
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Cote GM, Elliott CF, Lipplaa A, Gelderblom H, Blay JY, Le Cesne A, Duffaud F, Kesari S, George S, Somaiah N, Conley AP, Teleanu MV, Fröhling S, Schlenk RF, Bompas E, Schuetze SM, Chugh R, Choy E, Chemudupati T, Lozinsky S, Freed DM, Sommer J, Wendelberger B, Stacchiotti S. European Journal of Cancer, 2026 Aug 26; 244:Journal ArticleA pooled analysis of phase 2 clinical trials in advanced chordoma
DOI:10.1016/j.ejca.2026.116875 -
Armstrong AE, Minard-Colin V, Glod J, John S, Ramakrishna S, Ferrari A, Corradini N, D'Angelo SP, Blay J-Y, Van Tine BA, Schuetze SM, Haanen J, Chow WA, Ireland B, Bai J, Nathenson MJ, Van Winkle E, Williams D. Journal of Clinical Oncology, 2026 May 29; 44 (16_suppl): 11569 - 11569.Journal ArticleEfficacy and safety of engineered TCR-T cell therapy (afami-cel, lete-cel) in pediatric synovial sarcoma.
DOI:10.1200/jco.2026.44.16_suppl.11569 -
D'Angelo SP, Araujo DM, Razak A, Agulnik M, Butler MO, Druta M, Forcade E, Ganjoo KN, Le Cesne A, Schuetze SM, Strauss S, Thistlethwaite F, Valverde C, Wagner MJ, Nathenson MJ, Bai J, Williams D, Van Winkle E, McPherson S, Blay J-Y. Journal of Clinical Oncology, 2026 May 29; 44 (16_suppl): 11505 - 11505.Journal ArticlePooled analyses of clinical outcomes with afamitresgene autoleucel (afami-cel) in metastatic synovial sarcoma.
DOI:10.1200/jco.2026.44.16_suppl.11505 -
Merriam P, Morrow JJ, Mazzola E, Solimini NL, Gokhale PC, Chi P, Chen AP, Agulnik M, Burgess M, Schuetze SM, Somaiah N, Van Tine BA, Pollack SM, Tinoco G, Trent J, Wilky BA, Bothwick N, Eschle BK, Nguyen V, Beumer JH, Rastkari N, Jiwani S, Wu PI-F, Pelosof L, Hemming ML, Shapiro GI, Demetri G, Bernstein B, George S. Nat Med, 2026 May 26;Journal ArticleFibroblast growth factor receptor inhibition for succinate dehydrogenase-deficient gastrointestinal stromal tumors: a phase 2 trial.
DOI:10.1038/s41591-026-04376-9 PMID: 42191879 -
Bansal A, Stoffel EM, Lim R, Stanich PP, Patel SG, Burke CA, Hall MJ, Singh A, Boardman LA, Samadder NJ, Ballestar V, Muller C, Scott AJ, Benante KA, Xu Y, Eickhoff J, Hyun M, Zaborek J, Aquila L, Umar A, Szabo E, Della’Zanna G, Richmond E, Bengtson L, Schlom J, Donahue RN, Toney NJ, Horn LA, Palena C, Gulley JL, Samaddar S, Moore DF, Sharma P, Madan R, Hurley KE, Soon-Shiong P, Gabitzsch E, Sender L, Brenner D, Schuetze S, Djuric Z, Barroilhet LM, Thompson P, Bauman J, Khan SA, Vilar E. Frontiers in Immunology, 2026 May 20; 17: 1809281Journal ArticleDesign and preliminary report of a randomized phase IIb clinical trial of multitargeted recombinant adenovirus 5 vaccines against CEA, MUC1, and brachyury (Tri-Ad5) and the IL-15 receptor superagonist nogapendekin alfa inbakicept in Lynch syndrome (TRIAD5-Plus): the first cross-network trial of the Cancer Prevention Clinical Trials Network (CP-CTNet)
DOI:10.3389/fimmu.2026.1809281 -
Abu-Rustum NR, Campos SM, Amarnath S, Arend R, Barber E, Bradley K, Brooks R, Chino J, Chon HS, Crispens MA, Damast S, Fisher CM, Frederick P, Gaffney DK, Gaillard S, Giuntoli R, Glaser G, Glaser S, Howitt BE, Kendra K, Landrum L, Lea J, Lee N, Mantia-Smaldone G, Mariani A, Mutch D, Nagel C, Nekhlyudov L, Nwachukwu C, Podoll M, Rodabaugh K, Salani R, Schorge J, Schuetze S, Siedel J, Soliman P, Ueda S, Urban R, Wyse E, McMillian N, Sambandam V. J Natl Compr Canc Netw, 2026 Mar; 24 (3): 101 - 126.Journal ArticleVaginal Cancer, Version 2.2026, NCCN Clinical Practice Guidelines In Oncology.
DOI:10.6004/jnccn.2026.0011 PMID: 41825134 -
Raufi AG, Stoffel EM, Burke CA, Stanich P, Shah S, Wise P, Sen A, Della'Zanna G, Kress S, Bounds D, Ginsburg Y, Brenner DE, Prabhu VV, Djuric Z, Schuetze SM, El-Deiry WS. Journal of Clinical Oncology, 2026 Jan 14; 44 (2_suppl): tps246 - tps246.Proceeding / Abstract / PosterONC201 for chemoprevention of colorectal cancer.
DOI:10.1200/jco.2026.44.2_suppl.tps246 -
Wytiaz V, Marks A, Mayers A, Shami S, Schuetze S, Chugh R. Palliative Care and Social Practice, 2026 Jan 1; 20:Journal ArticleAn analysis of palliative care in adolescents and young adults with soft tissue and bone sarcomas
DOI:10.1177/26323524261415905
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