Lori J Pierce, MD
Department of Radiation Oncology
1500 E. Medical Center Dr. Rogel Cancer Center #4308
Ann Arbor, MI 48109
Manage Your Profile
About
Dr. Lori Pierce attended Duke University School of Medicine and completed a Radiation Oncology residency and chief residency at the Hospital of the University of Pennsylvania. She then was appointed as a Senior Investigator at the National Cancer Institute, National Institutes of Health in Bethesda, MD from 1990-1992. In 1992, Dr. Pierce joined the faculty of the University of Michigan where she is currently Professor with tenure in Radiation Oncology. Since coming to Michigan, she has served as residency director and clinical director in the Department of Radiation Oncology. In August 2005, Dr. Pierce was appointed by the University of Michigan Board of Regents to be Vice Provost for Academic and Faculty Affairs, a position she held until June, 2024.
Dr. Pierce has dedicated her career to the treatment of breast cancer patients. Her research focuses on the use of radiotherapy in the treatment of breast cancer, with emphasis on cardiac-sparing treatment planning, the use of radiosensitizing agents, and the outcomes of women treated with radiation for breast cancer who are carriers of a BRCA1/2 breast cancer susceptibility gene. She serves as Director of the Michigan Radiation Oncology Quality Consortium (MROQC), a quality consortium of radiation oncology practices across the state of Michigan that seeks to establish best practices in the treatment of breast and lung cancers. She is a previous member of the NCI Breast Cancer Steering Committee and the Steering Committee for the Early Breast Cancer Trialists’ Collaborative Group at the University of Oxford. She continues to serve on many U.S. breast cancer boards and committees and is a member of the Breast Cancer Research Foundation Scientific Advisory Board and the Damon Runyon board.
Dr. Pierce has published over 260 manuscripts and book chapters and has received numerous awards from the University of Michigan and multiple national organizations. Honors include receipt of the European Society of Therapeutic Radiology and Oncology travel award, the American Medical Association Women Physician Mentor Award, the American Association for Women Radiologists’ Marie Curie Award, the Conquer Cancer Foundation Endowed Women Who Conquer Cancer Mentorship Award, and selection as a Susan G. Komen for the Cure Scholar. Dr. Pierce was elected to the National Academy of Medicine, Class of 2018. She was the recipient of the 2021 Association of Community Cancer Centers Annual Achievement Award and the 2021 American Society for Radiation Oncology Gold Medal Award. In 2022, she received the OncLive Giants of Cancer Care, Community Outreach, Education and Cancer Policy Award. She is the 2023 recipient of the Vivian and Meyer P. Potamkin Foundation Prize for Breast Cancer Research. In 2018, she was elected president of the American Society of Clinical Oncology and served as Chair of the Society Board during 2021-22 and Past President and Chair of the Association Board in 2022-23.
Qualifications
-
ResidencyUniversity of Pennsylvania Health System, Radiation Oncology, Philadelphia, United States
1986 - 1988
Residency
-
InternshipThomas Jefferson University Hospital, Internal Medicine, Philadelphia, United States
1985 - 1986
Internship
Center Memberships
-
Center MemberInstitute for Healthcare Policy and Innovation
-
Center MemberRogel Cancer Center
Research Overview
Breast-conserving therapy for breast cancer
The effect of radiation in patients with BRCA-1 or BRCA-2 mutations
The use of intensity modulated radiotherapy in the treatment of breast cancer
Indications for post-mastectomy radiotherapy
The use of radiosensitizers in patients with refractory disease
Recent Publications
-
McBean B, Hauk B, Michmerhuizen AR, Chandler BC, Pesch AM, Lerner LM, Gurdak D, Ward C, Rana P, Zeidane RA, Mercer V, Tao M, Hochmuth E, Jungles KM, The S, Liu M, Spratt DE, Boyle AP, Pierce LJ, Speers CW. Npj Breast Cancer, 2026 Dec 1; 12 (1):Journal ArticleTranscriptomic analysis to uncover the mechanism of radiosensitization of AR-positive triple-negative breast cancers with AR inhibition
DOI:10.1038/s41523-026-00916-1 -
Monda SM, Odayar V, Yin M, Gonzalez RT, Jaime-Casas S, Hopfensperger KM, Kendrick D, Mietzel MA, Mislmani M, Zaki M, McLaughlin PW, Morgan TM, Jackson WC, Schipper MJ, Heimburger DK, Bryant AK, Pierce LJ, Borza T, Dess RT. Cancer, 2026 Nov 1; 132 (21):Journal ArticlePopulation-level diagnostic and radiation treatment trends of low-risk prostate cancer
DOI:10.1002/cncr.70603 -
Moncion A, Bains J, Grubb M, Yin H, Piersma N, Mietzel M, Matuszak M, Marsh R, Dess R, Vicini F, Pierce L, Covington E. Pract Radiat Oncol, 2026 Oct 14;Journal ArticleAdoption and Practice Patterns of TG-263 Standardized Nomenclature for Breast Radiation Therapy in a Statewide Quality Consortium.
DOI:10.1016/j.prro.2026.10.003 PMID: 42874869 -
Cousins MM, Higgins L, Dykstra MP, Yin H, Griffith K, Schipper M, Dominello MM, Sharma R, Johnson-Olokesusi J, Bavireddy V, Mietzel M, Kendrick D, Dess RT, Heimburger DK, Jolly S, Vicini FA, Pierce LJ, Covington E, Mierzwa ML. International Journal of Radiation Oncology • Biology • Physics, 2026 Sep 27; 126 (1): e325 - e326.Journal ArticleCharacterization of Cannabis Use In Patients with Prostate, Lung, and Breast Cancer Enrolled in a Statewide Multicenter Cohort
DOI:10.1016/j.ijrobp.2026.06.1373 -
Jagsi R, Meisner A, Chalasani P, Lew D, Barlow WE, Bellon JR, Henry NL, Matuszak MM, Moran JM, Pierce LJ, Rakovitc E, Reye SJ, Speers C, Unger JM, White JR, Woodward WA, Zellars RC, Pusztai L, Sharma P. Int J Radiat Oncol Biol Phys, 2026 Jul 28;Journal ArticleAdverse Events in a Randomized Trial Comparing Radiation Therapy With or Without Olaparib for Inflammatory Breast Cancer.
DOI:10.1016/j.ijrobp.2026.07.029 PMID: PMC13654406 -
Endraws MA, Jungles KM, Bishop C, Wilson C, Rana PS, Hauk B, Diedrich C, Markovic V, Hochmuth E, McBean BN, Liu M, Pierce L, Rae JM, Speers CW. Cancer Research, 2026 Apr 5; 86 (7_Supplement): 6604 - 6604.Proceeding / Abstract / PosterAbstract 6604: Aurora kinase B inhibition enhances radiation response and activates type 1 interferon signaling in triple-negative breast cancer.
DOI:10.1158/1538-7445.am2026-6604 -
Odayar V, Monda S, Yin H, Gonzalez RT, Casas SJ, Hopfensperger K, Kendrick D, Mietzel MA, Mislmani M, Zaki MA, McLaughlin PW, Morgan TM, Jackson WC, Schipper MJ, Heimburger DK, Bryant AK, Pierce LJ, Borza T, Dess RT. Journal of Clinical Oncology, 2026 Mar 4; 44 (7_suppl): 336 - 336.Proceeding / Abstract / PosterPopulation-level trends in radiation treatment of low-risk prostate cancer.
DOI:10.1200/jco.2026.44.7_suppl.336 -
Wilson RL, Giobbie-Hurder A, Bender CM, Brewster AM, Crane TE, Hopkins JO, Masters GA, Pierce LJ, Ligibel JA, Dieli-Conwright CM. JCO Oncology Practice, 2026 Feb 1; 21:Proceeding / Abstract / PosterBarriers to the Adoption of Healthy Lifestyle Behaviors in Patients With Cancer: Results of a National Survey
DOI:10.1200/OP-25-01029 PMID: 41701954
Featured News & Stories
Medical School’s Lori J. Pierce, MD, named Distinguished University Professor
Philanthropy in action: donors promote scholarship and leadership through intentional giving
Communication, ‘rethinking our system’ are keys to future of biomedical science