Lori J Pierce, MD
Professor of Radiation Oncology
Adjunct Professor of Nursing
School of Nursing
Department of Radiation Oncology
1500 E. Medical Center Dr. Rogel Cancer Center #4308
Ann Arbor, MI 48109
[email protected]

Available to mentor

Lori J Pierce, MD
Professor
  • About
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • About

    Dr. Lori Pierce attended Duke University School of Medicine and completed a Radiation Oncology residency and chief residency at the Hospital of the University of Pennsylvania. She then was appointed as a Senior Investigator at the National Cancer Institute, National Institutes of Health in Bethesda, MD from 1990-1992. In 1992, Dr. Pierce joined the faculty of the University of Michigan where she is currently Professor with tenure in Radiation Oncology. Since coming to Michigan, she has served as residency director and clinical director in the Department of Radiation Oncology. In August 2005, Dr. Pierce was appointed by the University of Michigan Board of Regents to be Vice Provost for Academic and Faculty Affairs, a position she still holds.

    Dr. Pierce has dedicated her career to the treatment of breast cancer patients. Her research focuses on the use of radiotherapy in the treatment of breast cancer, with emphasis on cardiac-sparing treatment planning, the use of radiosensitizing agents, and the outcomes of women treated with radiation for breast cancer who are carriers of a BRCA1/2 breast cancer susceptibility gene. She serves as Director of the Michigan Radiation Oncology Quality Consortium (MROQC), a quality consortium of radiation oncology practices across the state of Michigan that seeks to establish best practices in the treatment of breast and lung cancers. She is a previous member of the NCI Breast Cancer Steering Committee and the Steering Committee for the Early Breast Cancer Trialists’ Collaborative Group at the University of Oxford. She continues to serve on many U.S. breast cancer boards and committees and is a member of the Breast Cancer Research Foundation Scientific Advisory Board and the Damon Runyon board.

    Dr. Pierce has published over 260 manuscripts and book chapters and has received numerous awards from the University of Michigan and multiple national organizations. Honors include receipt of the European Society of Therapeutic Radiology and Oncology travel award, the American Medical Association Women Physician Mentor Award, the American Association for Women Radiologists’ Marie Curie Award, the Conquer Cancer Foundation Endowed Women Who Conquer Cancer Mentorship Award, and selection as a Susan G. Komen for the Cure Scholar. Dr. Pierce was elected to the National Academy of Medicine, Class of 2018. She was the recipient of the 2021 Association of Community Cancer Centers Annual Achievement Award and the 2021 American Society for Radiation Oncology Gold Medal Award. In 2022, she received the OncLive Giants of Cancer Care, Community Outreach, Education and Cancer Policy Award. She is the 2023 recipient of the Vivian and Meyer P. Potamkin Foundation Prize for Breast Cancer Research. In 2018, she was elected president of the American Society of Clinical Oncology and served as Chair of the Society Board during 2021-22 and Past President and Chair of the Association Board in 2022-23.

    Qualifications
    • Residency
      University of Pennsylvania Health System, Radiation Oncology, 1988
    • Internship
      Thomas Jefferson University Hospital, Internal Medicine, 1986
    Center Memberships
    • Center Member
      Institute for Healthcare Policy and Innovation
    • Center Member
      Rogel Cancer Center
    Research Overview

    Breast-conserving therapy for breast cancer
    The effect of radiation in patients with BRCA-1 or BRCA-2 mutations
    The use of intensity modulated radiotherapy in the treatment of breast cancer
    Indications for post-mastectomy radiotherapy
    The use of radiosensitizers in patients with refractory disease

    Recent Publications See All Publications
    • Journal Article
      Quality-of-Life Outcomes from NRG/NSABP B-39/RTOG 0413: Whole-breast Irradiation vs Accelerated Partial-breast Irradiation after Breast Conserving Surgery.
      Ganz PA, Cecchini RS, White JR, Vicini FA, Arthur DW, Rabinovitch RA, Kuske RR, Julian TB, Parda DS, Scheier MF, Winter KA, Paik S, Kuerer HM, Vallow LA, Pierce LJ, Mamounas EP, McCormick B, Bear HD, Germain I, Gustafson GS, Grossheim L, Petersen IA, Hudes RS, Curran WJ, Wolmark N. J Natl Cancer Inst, 2024 Sep 10; DOI:10.1093/jnci/djae219
      PMID: 39254630
    • Journal Article
      Are We Missing Acute Toxicities Associated With Hypofractionated Breast Irradiation? A Report From a Large Multicenter Cohort Study.
      Beydoun H, Griffith KA, Jagsi R, Burmeister JW, Moran JM, Vicini FA, Hayman JA, Paximadis P, Boike TP, Walker EM, Pierce LJ, Dominello MM. Int J Radiat Oncol Biol Phys, 2024 Jul 15; 119 (4): 1092 - 1098. DOI:10.1016/j.ijrobp.2024.01.225
      PMID: 38364950
    • Journal Article
      Oncologist-Reported Barriers and Facilitators to Offering Cancer Clinical Trials to Their Patients.
      Castillo BS, Boehmer L, Schrag J, Howson A, Oyer R, Pierce L, Barrett NJ, Guerra CE. Curr Oncol, 2024 May 28; 31 (6): 3017 - 3029. DOI:10.3390/curroncol31060230
      PMID: 38920714
    • Proceeding / Abstract / Poster
      Abstract 708: Targeting aurora kinase B (AURKB) as a radiosensitizing strategy in syngeneic models of triple negative breast cancer (TNBC)
      Jungles KM, Wang Z, Bishop C, Wilson C, Liu M, James J, Green M, Rae JM, Speers CW, Pierce LJ. Cancer Research, 2024 Mar 22; 84 (6_Supplement): 708 - 708. DOI:10.1158/1538-7445.am2024-708
    • Journal Article
      Factors Associated With Cardiac Radiation Dose Reduction After Hypofractionated Radiation Therapy for Localized, Left-Sided Breast Cancer in a Large Statewide Quality Consortium.
      Herr DJ, Moncion A, Griffith KA, Marsh R, Grubb M, Bhatt A, Dominello M, Walker EM, Narayana V, Abu-Isa E, Vicini FA, Hayman JA, Pierce LJ, Michigan Radiation Oncology Quality Consortium . Int J Radiat Oncol Biol Phys, 2024 Mar 1; 118 (3): 632 - 638. DOI:10.1016/j.ijrobp.2023.09.013
      PMID: 37797748
    • Journal Article
      Partial Breast Irradiation for Patients With Early-Stage Invasive Breast Cancer or Ductal Carcinoma In Situ: An ASTRO Clinical Practice Guideline.
      Shaitelman SF, Anderson BM, Arthur DW, Bazan JG, Bellon JR, Bradfield L, Coles CE, Gerber NK, Kathpal M, Kim L, Laronga C, Meattini I, Nichols EM, Pierce LJ, Poppe MM, Spears PA, Vinayak S, Whelan T, Lyons JA. Pract Radiat Oncol, 2024 14 (2): 112 - 132. DOI:10.1016/j.prro.2023.11.001
      PMID: 37977261
    • Additional Scholarship
      Everyone Plays A Role In Improving Cancer Health Equity
      Fawcett N. 2024 Jan 19;
    • Journal Article
      Pectoralis Muscle Dosimetry and Posttreatment Rehabilitation Utilization for Patients With Early-Stage Breast Cancer.
      Takayesu JSK, Jiang SJ, Marsh R, Moncion A, Smith SR, Pierce LJ, Jagsi R, Lipps DB. Pract Radiat Oncol, 2024 14 (1): e20 - e28. DOI:10.1016/j.prro.2023.07.006
      PMID: 37768242
    Featured News & Stories Sally A. Camper, Ph.D., and Lori J. Pierce, M.D.
    Medical School News
    Sally A. Camper, Ph.D., and Lori J. Pierce, M.D., to receive Muraszko Award
    Two Medical School leaders are being honored for their efforts to help women forge successful careers in academic medicine and science. Sally A. Camper, Ph.D., and Lori J. Pierce, M.D., will receive the Karin Muraszko, M.D., Advancing Women in Academic Medicine and Science Award on Feb. 5 at the third annual Celebration of Women in Academic Medicine and Science.