Available to mentor
Dr. Curtis received his medical degree from the Georgetown University School of Medicine. After a clinical residency in internal medicine and a year as Chief Medical Resident at the Johns Hopkins Bayview Medical Center, he spent two years as a Clinical Immunology Fellow at the National Institute on Aging, NIH. He then trained in Pulmonary & Critical Care Medicine (PCCM) at the University of California San Francisco, then joined the UCSF faculty at the San Francisco VA. Dr. Curtis was previously Chief, PCCM Section at the VA Ann Arbor Healthcare System (VAAAHS, 1990-2014) where he was scientific director of a Research Enhancement Award Program center in tobacco-induced lung diseases (1999-2012). He has held leadership roles in multiple COPD clinical trials, including the ongoing SPIROMICS, SOURCE, and COPDGene® studies. He is an Associate Editor of the American Journal of Respiratory & Critical Care Medicine and past-Chair of the American Thoracic Society (ATS) Scientific Assembly on Allergy, Immunology & Inflammation, from which he received a lifetime scientific achievement award in 2019. He received the Roger B. Grekin award from VAAAHS (2017); the John B. Barnwell award (named for the University of Michigan’s first Pulmonary Division Chief), VA’s highest award for clinical research (2019; and a Distinguished Achievement Award from ATS (2024). Dr. Curtis is an avid cyclist and downhill skier who enjoys cooking and eating many international cuisines, and reading, especially fiction and world history.
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Moll M, Hecker J, Platig J, Zhang J, Ghosh AJ, Pratte KA, Wang R-S, Hill D, Konigsberg IR, Chiles JW, Hersh CP, Castaldi PJ, Glass K, Dy JG, Sin DD, Tal-Singer R, Mouded M, Rennard SI, Anderson GP, Kinney GL, Bowler RP, Curtis JL, McDonald M-L, Silverman EK, Hobbs BD, Cho MH. EBioMedicine, 2024 Nov 6; 110: 105429Journal ArticlePolygenic and transcriptional risk scores identify chronic obstructive pulmonary disease subtypes in the COPDGene and ECLIPSE cohort studies.
DOI:10.1016/j.ebiom.2024.105429 PMID: 39509750 -
Arjomandi M, Zeng S, Barjaktarevic I, Bleecker ER, Bowler RP, Criner GJ, Comellas AP, Couper DJ, Curtis JL, Dransfield MT, Drummond MB, Fortis S, Han MK, Hansel NN, Hoffman EA, Kaner RJ, Kanner RE, Krishnan JA, Labaki W, Ortega VE, Peters SP, Rennard SI, Cooper CB, Tashkin DP, Paine R, Woodruff PG. Ann Am Thorac Soc, 2024 Nov 25;Journal ArticlePhenotypes and Trajectories of Tobacco-exposed Persons with Preserved Spirometry: Insights from Lung Volumes.
DOI:10.1513/AnnalsATS.202405-527OC PMID: 39586032 -
Guo CJ, Godbole S, Labaki WW, Pratte KA, Curtis JL, Paine R, Hoffman E, Han M, Ohar J, Cooper C, Kechris KJ, DeMeo DL, Bowler RP. Metabolites, 14 (12): 647Journal ArticleMetabolic Aging as an Increased Risk for Chronic Obstructive Pulmonary Disease
DOI:10.3390/metabo14120647 -
Suri R, Markovic D, Woo H, Arjomandi M, Barr RG, Bowler RP, Criner G, Curtis JL, Dransfield MT, Drummond MB, Fortis S, Han MK, Hoffman EA, Kaner RJ, Kaufman JD, Krishnan JA, Martinez FJ, Ohar J, Ortega VE, Paine R, Soler X, Woodruff PG, Hansel NN, Cooper CB, Tashkin DP, Buhr RG, Barjaktarevic IZ. Am J Respir Crit Care Med, 2024 Nov 15; 210 (10): 1210 - 1218.Journal ArticleThe Effect of Chronic Altitude Exposure on Chronic Obstructive Pulmonary Disease Outcomes in the SPIROMICS Cohort: An Observational Cohort Study.
DOI:10.1164/rccm.202310-1965OC PMID: 38507607 -
DiLillo KM, Ruvuna L, Pratte KA, Serban KA, Labaki WW, Han MK, Freeman CM, Bowler RP, Curtis JL, Arnold KB. Am J Respir Crit Care Med, 2024 Nov 15; 210 (10): 1269 - 1272.Journal ArticleValidation of Systemic Complement Signatures in the Progression of Chronic Obstructive Pulmonary Disease.
DOI:10.1164/rccm.202311-2059LE PMID: 39311978 -
Burnim M, Putcha N, LaFon D, Woo H, Azar A, Groenke L, Stampfli M, Schaub A, Fawzy A, Balasubramanian A, Fedarko N, Cooper CB, Bowler RP, Comellas A, Krishnan JA, Han MK, Couper D, Peters SP, Drummond MB, O'Neal W, Paine R, Criner G, Martinez FJ, Curtis JL, Barr G, Huang YJ, Woodruff P, Dransfield M, Hansel NN. Am J Respir Crit Care Med, 2024 Oct 23;Journal ArticleSerum Immunoglobulin G Levels Are Associated with Risk for Exacerbations: An Analysis of SPIROMICS.
DOI:10.1164/rccm.202311-2184OC PMID: 39441116 -
Moll M, Xu Z, Boueiz A, Ryu MH, Silverman EK, Cho MH, Hersh CP, Sauler M, Polverino F, Kinney GL, Curtis JL, Crotty-Alexander LE, Vollmers C, Castaldi PJ. medRxiv, 2024 Oct 8;Journal ArticleB cell immune repertoire sequencing in tobacco cigarette smoking, vaping, and chronic obstructive pulmonary disease in the COPDGene cohort.
DOI:10.1101/2024.10.07.24315038 PMID: 39417147 -
Kosiborod MN, Windsor SL, Vardeny O, Berger JS, Reynolds HR, Boumakis S, Althouse AD, Solomon SD, Bhatt AS, Peikert A, Luther JF, Leifer ES, Kindzelski AL, Cushman M, Ng Gong M, Kornblith LZ, Khatri P, Kim KS, Baumann Kreuziger L, Javaheri A, Carpio C, Wahid L, Lopez-Sendon Moreno J, Alonso A, Ho MQ, Lopez-Sendon J, Lopes RD, Curtis JL, Kirwan B-A, Geraci MW, Neal MD, Hochman JS, ACTIV-4a Investigators . Lancet Diabetes Endocrinol, 2024 Oct; 12 (10): 725 - 734.Journal ArticleEffect of sodium-glucose co-transporter-2 inhibitors on survival free of organ support in patients hospitalised for COVID-19 (ACTIV-4a): a pragmatic, multicentre, open-label, randomised, controlled, platform trial.
DOI:10.1016/S2213-8587(24)00218-3 PMID: 39250922