J Scott VanEpps, MD, PhD
Associate Professor of Emergency Medicine
Associate Professor of Macromolecular Sciences and Engineering
Emergency Medicine
2800 Plymouth Rd, NCRC #14-117
Ann Arbor, MI 48108
[email protected]

Available to mentor

J Scott VanEpps, MD, PhD
Associate Professor
  • About
  • Links
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • About

    Dr. VanEpps is an Associate Professor in the Department of Emergency Medicine and the Department of Biomedical Engineering at the University of Michigan. He is also faculty in the Biointerfaces Institute and the Associate Director for the Weil Institute for Critical Care Research and Innovation. He received bachelor’s degrees from the University of Pittsburgh in Molecular Biology and Chemical Engineering in 2001. He then entered the Medical Scientist Training Program at the University of Pittsburgh and obtained his MD as well as his PhD in Bioengineering in 2009. He completed his residency in Emergency Medicine at the University of Michigan/St. Joseph Mercy Hospital in 2013 and joined the faculty at the University of Michigan. He is board certified in Emergency Medicine and sees patients in the Adult Emergency Department and the Emergency Critical Care Center at Michigan Medicine.

    Links
    • VanEpps Lab
    • Departmental webpage
    • VanEpps ResearchGate
    • VanEpps LinkedIn
    Qualifications
    • Research Fellowship
      University of Michigan–Ann Arbor, Emergency Medicine, 2015
    • Emergency Medicine
      University of Michigan–Ann Arbor, Emergency Medicine, 2013
    • PhD
      University of Pittsburgh, Benedum Hall 3700 O'Hara St, 2009
    • MD
      University of Pittsburgh, 401 Scaife Hall 3550 Terrace Street, 2009
    • BS
      University of Pittsburgh, Pittsburgh, 2001
    • BS
      University of Pittsburgh, Pittsburgh, 2001
    Center Memberships
    • Center Member
      Center for Integrative Research in Critical Care
    • Center Member
      Biointerfaces Institute
    • Center Member
      Global REACH
    • Center Member
      Taubman Institute
    • Center Member
      MM-PKUHSC Joint Institute
    • Center Member
      e-Health and Artificial Intelligence Initiative
    Research Overview

    During his doctoral training, Dr. VanEpps’ research focused on the relationship between cardiovascular biomechanics and the development of coronary artery disease. He has developed custom designed ex vivo perfusion systems to recreate realistic in vivo cardiovascular fluid and solid mechanics in the laboratory. In addition, he has extensive experience in computational modeling including finite element analysis and computational fluid dynamics. His research is currently focused on life threatening infections, and in particular those related to implantable medical devices. That work is divided into both rapid diagnostics for bloodstream infection as well as novel treatment strategies. With respect to diagnostics his lab is developing a PCR assay to detect bacteria in whole blood without culture. With respect to treating medical device related infection, his lab focus on fundamental understanding of bacterial adhesion to abiotic surfaces, the development of novel nanomaterials to prevent adhesion and colonization of surfaces, and new strategies to treat implanted medical device infection in situ. Technologies under development include, novel antimicrobial/antibiofilm nanomaterials, physical augmentation of antibiotic killing, and biofilm dispersal agents

    Recent Publications See All Publications
    • Journal Article
      Continuous sepsis trajectory prediction using tensor-reduced physiological signals.
      Alge OP, Pickard J, Zhang W, Cheng S, Derksen H, Omenn GS, Gryak J, VanEpps JS, Najarian K. Sci Rep, 2024 Aug 6; 14 (1): 18155 DOI:10.1038/s41598-024-68901-x
      PMID: 39103488
    • Patent
      Method and Apparatus For Stacked Multi-Filter Device For Customized Fluid Sample Filtration And Extraction
      Wellman C, Smith C, Bugga P, Asthana V, VanEpps J.
    • Preprint
      GenomicGapID: Leveraging Spatial Distribution of Conserved Genomic Sites for Broad-Spectrum Microbial Identification
      Asthana V, Bugga P, Smith CE, Wellman C, Dwight Z, Ranjan P, Nieves EM, Dickson R, VanEpps S. 2024 bioRxiv, DOI:10.1101/2024.10.07.617038
    • Journal Article
      ANTIMICROBIAL WOUND DRESSINGS FOR FULL-THICKNESS INFECTED BURN WOUNDS.
      Dhyani A, Repetto T, VanAken S, Nemzek J, VanEpps JS, Mehta G, Tuteja A. Shock, 2024 Oct 1; 62 (4): 588 - 595. DOI:10.1097/SHK.0000000000002426
      PMID: 39158545
    • Preprint
      A rapid, inexpensive, culture-free, universal bacterial identification system using internal transcribed spacer targeting primers: a proof-of-principle study
      Asthana V, Nieves EM, Bugga P, Smith C, Dunn T, Narayanasamy S, Dickson R, VanEpps S. 2024 bioRxiv, DOI:10.1101/2024.09.15.613074
    • Preprint
      Coupled Self-Replication and Self-Assembly of Inorganic Nanoparticles into Biosimilar Networks
      Kotov N, McGlothin C, Whisnant K, Turali-Emre E, Owuor D, Xiao XY, Bogdan P, VanEpps JS. Research Square, DOI:10.21203/rs.3.rs-4516820/v1
    • Presentation
      Current evidence for sepsis endotyping and implications for future changes in emergency practice
      VanEpps J. 2024 Jun;
    • Journal Article
      Rapid diagnosis of bloodstream infections using a culture-free phenotypic platform.
      Shi X, Sharma S, Chmielewski RA, Markovic MJ, VanEpps JS, Yau S-T. Commun Med (Lond), 2024 Apr 23; 4 (1): 77 DOI:10.1038/s43856-024-00487-x
      PMID: 38654117