J Scott VanEpps, MD, PhD, FACEP
Emergency Medicine
2800 Plymouth Rd, NCRC #14-117
Ann Arbor, MI 48108
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About
Dr. VanEpps is an Associate Professor in the Department of Emergency Medicine and the Department of Biomedical Engineering at the University of Michigan. He is also faculty in the Biointerfaces Institute and the Associate Director for the Weil Institute for Critical Care Research and Innovation. He received bachelor’s degrees from the University of Pittsburgh in Molecular Biology and Chemical Engineering in 2001. He then entered the Medical Scientist Training Program at the University of Pittsburgh and obtained his MD as well as his PhD in Bioengineering in 2009. He completed his residency in Emergency Medicine at the University of Michigan/St. Joseph Mercy Hospital in 2013 and joined the faculty at the University of Michigan. He is board certified in Emergency Medicine and sees patients in the Adult Emergency Department and the Emergency Critical Care Center at Michigan Medicine.
Links
VanEpps Lab Departmental webpage VanEpps ResearchGate VanEpps LinkedIn
Qualifications
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Chair Development ProgramSociety for Academic Emergency Medicine, Des Plaines, United States
2025 - 2026
Postdoctoral Fellowship
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Research FellowshipUniversity of Michigan–Ann Arbor, Emergency Medicine, Ann Arbor, United States
2013 - 2015
Postdoctoral Fellowship
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Emergency MedicineUniversity of Michigan–Ann Arbor, Emergency Medicine, Ann Arbor, United States
2009 - 2013
Residency
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PhD, BioengineeringUniversity of Pittsburgh, Benedum Hall 3700 O'Hara St, Pittsburgh, PA, 15261, United States
2001 - 2009
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MDUniversity of Pittsburgh, 401 Scaife Hall 3550 Terrace Street, Pittsburgh, PA, 15261, United States
2001 - 2009
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BS, Molecular Biology, Summa Cum LaudeUniversity of Pittsburgh, Pittsburgh, PA, United States
1996 - 2001
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BS, Chemical Engineering, Summa Cum LaudeUniversity of Pittsburgh, Pittsburgh, PA, United States
1996 - 2001
Center Memberships
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Center MemberWeil Institute for Critical Care Research
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Center MemberBiointerfaces Institute
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Center MemberGlobal REACH
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Center MemberTaubman Institute
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Center Membere-Health and Artificial Intelligence Initiative
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Center MemberMM-PKUHSC Joint Institute
Research Overview
During his doctoral training, Dr. VanEpps’ research focused on the relationship between cardiovascular biomechanics and the development of coronary artery disease. He has developed custom designed ex vivo perfusion systems to recreate realistic in vivo cardiovascular fluid and solid mechanics in the laboratory. In addition, he has extensive experience in computational modeling including finite element analysis and computational fluid dynamics. His research is currently focused on life threatening infections, and in particular those related to implantable medical devices. That work is divided into both rapid diagnostics for bloodstream infection as well as novel treatment strategies. With respect to diagnostics his lab is developing a PCR assay to detect bacteria in whole blood without culture. With respect to treating medical device related infection, his lab focus on fundamental understanding of bacterial adhesion to abiotic surfaces, the development of novel nanomaterials to prevent adhesion and colonization of surfaces, and new strategies to treat implanted medical device infection in situ. Technologies under development include, novel antimicrobial/antibiofilm nanomaterials, physical augmentation of antibiotic killing, and biofilm dispersal agents
Recent Publications
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Tertel R, VanEpps JS, Muraglia KA. Annals of Emergency Medicine, 2026 Oct 4; 88 (4): s18 - s19.Journal Article44 Reversibility of Heat and Shear-Induced Endothelial Barrier Dysfunction
DOI:10.1016/j.annemergmed.2026.08.048 -
VanEpps JS. 2026 Sep 21;PresentationNanoparticle-biomolecule interactions: The next horizon for antibiotics
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Sharma S, Salaudeen HD, Ransom EM, VanEpps JS, Yau ST. Microbiology Spectrum, 2026 Sep 1; 14 (9):Journal ArticleA rapid approach to detect methicillin-resistant and susceptible Staphylococcus aureus directly from clinical specimens
DOI:10.1128/spectrum.00487-26 PMID: 42549908 -
Abriat C, Huang L, Sunder S, Bauman JS, Landry GA, Mueller HRL, VanEpps JS, Solomon MJ, Kumar A. Biofilm, 2026 Jun; 11: 100369Journal ArticleThe rheological properties of Candida albicans colony biofilms are impacted by matrix production and cell wall structure.
DOI:10.1016/j.bioflm.2026.100369 PMID: PMC13197771 -
Cummings B, Farzaneh N, Craig D, VanEpps JS, Bailey R, Reddy M, Ubokudom K, Foley K, Duffy E, Ito T, Ramilo O, Mahajan P. 2026 May 20;Proceeding / Abstract / PosterA novel proof-of-concept data platform integrating Physiologic, Laboratory, and Transcriptomic Biomarkers for ED based Pediatric Sepsis Screening
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Mahajan P, Cummings B, Farzaneh N, Craig D, VanEpps JS, Bailey R, Reddy M, Ubokudom K, Foley K, Duffy E, Ito T, Ramilo O. 2026 May 21;Proceeding / Abstract / PosterHost Transcriptome Response in Emergency Department Pediatric Sepsis Screening and Diagnosis
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Cummings B, Farzaneh N, Craig D, VanEpps JS, Bailey R, Reddy M, Ubokudom K, Foley K, Duffy E, Ito T, Ramilo O, Mahajan P. 2026 May 20;Proceeding / Abstract / PosterIdentifying Pediatric Sepsis in the Emergency Department
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Muraglia K, VanEpps JS. 2026 May 21;Proceeding / Abstract / PosterMechanism of Thermal Injury After a Heat-Based Therapy for Central Line Infection
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