Eric R Fearon
Emanuel N Maisel Professor of Oncology
Director, University of Michigan Rogel Cancer Center
Associate Dean for Cancer Programs
Professor of Internal Medicine
Professor of Pathology
Professor of Human Genetics
Medical School
[email protected]
Available to mentor
Eric R Fearon
Professor
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Center Memberships
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Center MemberRogel Cancer Center
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Center MemberAI and Digital Health Innovation
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Center MemberCenter for Cell Plasticity and Organ Design
Recent Publications
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Wang SH, Cao Z, Janczak KW, Feng Y, Green M, Tang S, Fearon ER, Baker JR. Cancer Gene Ther, 2026 Apr 25;Journal ArticleA p53 peptide mucosal vaccine induces cellular and humoral immunity and anti-tumor effects in a murine colorectal cancer model.
DOI:10.1038/s41417-026-01035-6 PMID: 42034727 -
Du Y, Luo L, Kim J-H, West B, Larman T, Cope L, Fearon ER, Sears C, Resar L. Cancer Research, 2026 Apr 5; 86 (7_Supplement): 4752 - 4752.Journal ArticleAbstract 4752: HMGA1: An epigenetic driver of colon carcinogenesis by inducing FGF19 signals which can be targeted with FGFR4 receptor blockade
DOI:10.1158/1538-7445.am2026-4752 -
Sada H, Niitsu H, Urabe Y, Nakahara H, Kochi M, Sakamoto N, Sotomaru Y, Tashiro H, Oka S, Ohdan H, Fearon ER, Hinoi T. Cell Mol Gastroenterol Hepatol, 2026 Mar 25; 101773Journal ArticleColon-Restricted Phosphatase and Tensin Homolog Deleted From Chromosome 10 Haploinsufficiency Models Phosphoinositide 3-Kinase Pathway-Driven Invasion in Colorectal Cancer.
DOI:10.1016/j.jcmgh.2026.101773 PMID: 41895684 -
Zhai Y, Bedi K, Wu R, Feng Y, Green ME, Pearce CL, Pike MC, Fearon ER, Cho KR. Cancers, 2025 Nov 1; 17 (21):Journal ArticleMedroxyprogesterone Acetate Inhibits Tumorigenesis in Mouse Models of Oviductal High-Grade Serous Carcinoma
DOI:10.3390/cancers17213456 -
Wang S, Cao Z, Janczak K, Feng Y, Green M, Tang S, Fearon E, Baker J. 2025 Oct 24; Research Square,PreprintA p53 peptide mucosal vaccine induces cellular and humoral immunity and anti-tumor effects in a murine colorectal cancer model
DOI:10.21203/rs.3.rs-7652612/v1 -
Zhai Y, Fearon ER, Cho KR. Cancers, 2025 Sep 1; 17 (17):Journal ArticleBilateral Salpingo-Oophorectomy Is Superior to Salpingectomy Alone in Preventing Non-Tubal Tumor Development in a Mouse Model of High-Grade Serous Carcinoma
DOI:10.3390/cancers17172759 -
Tien JCY, Zhai Y, Wu R, Zhang Y, Chang Y, Cheng Y, Todd AJ, Wheeler CE, Li S, Mannan R, Cheng C, Magnuson B, Cruz G, Cao Y, Mahapatra S, Stolfi C, Cao X, Su F, Wang R, Yang J, Zhou L, Qiao Y, Xiao L, Cieslik M, Wang X, Wang Z, Chou J, Fearon ER, Ding K, Cho KR, Chinnaiyan AM. Proceedings of the National Academy of Sciences of the United States of America, 2025 Jun 17; 122 (24):Journal ArticleDefining CDK12 as a tumor suppressor and therapeutic target in mouse models of tubo-ovarian high-grade serous carcinoma
DOI:10.1073/pnas.2426909122 PMID: 40504161 -
Feng Y, Zhu N, Bedi K, Li J, Perera C, Green M, Assarzadegan N, Zhai Y, Liu Q, Baladandayuthapani V, Spence JR, Cho KR, Fearon ER. Journal of Clinical Investigation, 2025 Jun 2; 135 (11):Journal ArticleSOX9 suppresses colon cancer via inhibiting epithelial-mesenchymal transition and SOX2 induction
DOI:10.1172/JCI184115 PMID: 40179020
Featured News & Stories
News Release
Ribbon-cutting for new pancreatic cancer program
The Rogel and Blondy Center for Pancreatic Cancer was officially launched with a special ribbon-cutting ceremony on the sixth floor of the Rogel Cancer Center.
Health Lab
Researchers identify roles of key genes in colon cancer development
Researchers used mouse models and studies of colorectal cancer tissues to show that loss of SOX9 gene promotes tumor progression and the pathway it regulates can be a potential target for future treatments.
Department News
Highlighted Publications - April 2025
Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.
