James M Rae
Thomas H Simpson Collegiate Professor of Cancer Research
Associate Professor of Internal Medicine
Associate Professor of Pharmacology
[email protected]

Available to mentor
James M Rae
Associate Professor
  • Center Memberships
  • Recent Publications
    • Center Memberships
    • Center Member
      Rogel Cancer Center
    Recent Publications See All Publications
    • Journal Article
      Incorporation of emergent symptoms and genetic covariates improves prediction of aromatase inhibitor therapy discontinuation.
      Rattsev I, Stearns V, Blackford AL, Hertz DL, Smith KL, Rae JM, Taylor CO. JAMIA Open, 2024 Apr; 7 (1): ooae006 DOI:10.1093/jamiaopen/ooae006
      PMID: 38250582
    • Journal Article
      Abstract 708: Targeting aurora kinase B (AURKB) as a radiosensitizing strategy in syngeneic models of triple negative breast cancer (TNBC)
      Jungles KM, Wang Z, Bishop C, Wilson C, Liu M, James J, Green M, Rae JM, Speers CW, Pierce LJ. Cancer Research, 2024 Mar 22; 84 (6_Supplement): 708 - 708. DOI:10.1158/1538-7445.am2024-708
    • Journal Article
      Attempted replication of pharmacogenetic association of variants in PPP1R14C and CCDC148 with aromatase inhibitor-induced musculoskeletal symptoms.
      Liang Y, Gersch CL, Lehman J, Henry NL, Smith KL, Rae JM, Stearns V, Hertz DL. Pharmacogenet Genomics, 2024 Feb 8; DOI:10.1097/FPC.0000000000000522
      PMID: 38359166
    • Journal Article
      Discovery of ERD-3111 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader with Strong Antitumor Activity.
      Chen Z, Hu B, Rej RK, Wu D, Acharyya RK, Wang M, Xu T, Lu J, Metwally H, Wang Y, McEachern D, Bai L, Gersch CL, Wang M, Zhang W, Li Q, Wen B, Sun D, Rae JM, Wang S. J Med Chem, 2023 Sep 14; 66 (17): 12559 - 12585. DOI:10.1021/acs.jmedchem.3c01186
      PMID: 37647546
    • Journal Article
      Effects of CYP3A4 and CYP2C9 genotype on systemic anastrozole and fulvestrant concentrations in SWOG S0226.
      Rutherford DV, Medley S, Henderson NC, Gersch CL, Vandenberg TA, Albain KS, Dakhil SR, Tirumali NR, Gralow JR, Hortobagyi GN, Pusztai L, Mehta RS, Hayes DF, Kidwell KM, Henry NL, Barlow WE, Rae JM, Hertz DL. Pharmacogenomics, 2023 Aug; 24 (12): 665 - 673. DOI:10.2217/pgs-2023-0097
      PMID: 37615099
    • Journal Article
      Targeting the Estrogen Receptor for the Treatment of Breast Cancer: Recent Advances and Challenges.
      Rej RK, Thomas JE, Acharyya RK, Rae JM, Wang S. J Med Chem, 2023 Jul 13; 66 (13): 8339 - 8381. DOI:10.1021/acs.jmedchem.3c00136
      PMID: 37377342
    • Journal Article
      The radiosensitizing effects of monopolar spindle kinase I in syngeneic models of triple negative breast cancer and its implications on the tumor immune microenvironment
      Jungles KM, Wang Z, Bishop C, Jungles KR, Wilson C, Liu M, Pearson AN, Holcomb EA, James J, Chandler B, Huber A, Speers CW, Rae J, Green M. The Journal of Immunology, 2023 May 1; 210 (1_Supplement): 245.06 - 245.06. DOI:10.4049/jimmunol.210.supp.245.06
    • Journal Article
      Abstract 2823: Targeting monopolar spindle kinase I (TTK) as a radiosensitizing strategy in syngeneic murine models of triple negative breast cancer (TNBC) and its implications on the tumor immune microenvironment
      Jungles KM, Wang Z, Bishop CR, Jungles KR, Wilson C, Liu M, Pearson AN, Holcomb EA, Chandler B, James J, Huber A, Pierce LJ, Speers C, Rae JM, Green MD. Cancer Research, 2023 Apr 4; 83 (7_Supplement): 2823 - 2823. DOI:10.1158/1538-7445.am2023-2823