Adjunct Professor of Molecular and Integrative Physiology
Adjunct Professor of Internal Medicine
[email protected]
Available to mentor
Ling Qi
Adjunct Professor
-
Center MemberCaswell Diabetes Institute
-
Podolsky MJ, Kheyfets B, Pandey M, Beigh AH, Yang CD, Lizama CO, Datta R, Lin LL, Wang Z, Wolters PJ, McManus MT, Qi L, Atabai K. Nat Commun, 2024 Feb 20; 15 (1): 1531Journal ArticleGenome-wide screens identify SEL1L as an intracellular rheostat controlling collagen turnover.
DOI:10.1038/s41467-024-45817-8 PMID: 38378719 -
Wei X, Lu Y, Lin LL, Zhang C, Chen X, Wang S, Wu SA, Li ZJ, Quan Y, Sun S, Qi L. Nat Commun, 2024 Jan 22; 15 (1): 659Journal ArticleProteomic screens of SEL1L-HRD1 ER-associated degradation substrates reveal its role in glycosylphosphatidylinositol-anchored protein biogenesis.
DOI:10.1038/s41467-024-44948-2 PMID: 38253565 -
Lin LL, Wang HH, Pederson B, Wei X, Torres M, Lu Y, Li ZJ, Liu X, Mao H, Wang H, Zhou LE, Zhao Z, Sun S, Qi L. Nat Commun, 2024 Apr 15; 15 (1): 3241Journal ArticlePublisher Correction: SEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex.
DOI:10.1038/s41467-024-47251-2 PMID: 38622165 -
Mao H, Kim GH, Pan L, Qi L. Nat Commun, 2024 Sep 29; 15 (1): 8435Journal ArticleRegulation of leptin signaling and diet-induced obesity by SEL1L-HRD1 ER-associated degradation in POMC expressing neurons.
DOI:10.1038/s41467-024-52743-2 PMID: 39343970 -
Lin LL, Wang HH, Pederson B, Wei X, Torres M, Lu Y, Li ZJ, Liu X, Mao H, Wang H, Zhou LE, Zhao Z, Sun S, Qi L. Nat Commun, 2024 Feb 16; 15 (1): 1440Journal ArticleSEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex.
DOI:10.1038/s41467-024-45633-0 PMID: 38365914 -
Torres M, Pederson B, Wang H, Lin LL, Wang HH, Bugarin-Lapuz A, Zhao Z, Qi L. JCI Insight, 2024 Nov 8; 9 (21):Journal ArticlePurkinje cell-specific deficiency in SEL1L-hrd1 endoplasmic reticulum-associated degradation causes progressive cerebellar ataxia in mice.
DOI:10.1172/jci.insight.174725 PMID: 39352758 -
Zhou L, Qiu X, Meng Z, Liu T, Chen Z, Zhang P, Kuang H, Pan T, Lu Y, Qi L, Olson DP, Xu XZS, Chen YE, Li S, Lin JD. Sci Transl Med, 2024 Mar 13; 16 (738): eadk1866Journal ArticleHepatic danger signaling triggers TREM2+ macrophage induction and drives steatohepatitis via MS4A7-dependent inflammasome activation.
DOI:10.1126/scitranslmed.adk1866 PMID: 38478630 -
Weis D, Lin LL, Wang HH, Li ZJ, Kusikova K, Ciznar P, Wolf HM, Leiss-Piller A, Wang Z, Wei X, Weis S, Skalicka K, Hrckova G, Danisovic L, Soltysova A, Yang TT, Feichtinger RG, Mayr JA, Qi L. J Clin Invest, 2024 Jan 16; 134 (2):Journal ArticleBiallelic Cys141Tyr variant of SEL1L is associated with neurodevelopmental disorders, agammaglobulinemia, and premature death.
DOI:10.1172/JCI170882 PMID: 37943617
