Subramaniam Pennathur, MD

 Subramaniam Pennathur photo
Norman Radin Professor of Nephrology
Professor of Internal Medicine
Professor of Molecular and Integrative Physiology
Section Head, Division of Nephrology
Medical School
[email protected]
Available to mentor
Subramaniam Pennathur, MD
Subramaniam Pennathur photo
Professor
  • Qualifications
  • Center Memberships
  • Recent Publications

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    • Qualifications
    • Chief Resident Karl-Flance Firm
      Washington University in St. Louis, Internal Medicine, St Louis, United States
      2001 - 2002
      Postdoctoral Fellowship
    • Fellow in Nephrology and Transplantation
      Washington University in St. Louis School of Medicine, St Louis, United States
      1999 - 2001
      Postdoctoral Fellowship
    • Fellow in Endocrinology
      Washington University in St. Louis School of Medicine, Diabetes and Metabolism, St Louis, United States
      1996 - 1999
      Postdoctoral Fellowship
    • Resident in Medicine
      Washington University in St. Louis School of Medicine, St Louis, United States
      1993 - 1996
      Postdoctoral Fellowship
    • Research Fellow
      Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
      1991 - 1993
      Postdoctoral Fellowship

    Center Memberships
    • Center Member
      MM-PKUHSC Joint Institute
    • Center Member
      Center for Computational Medicine and Bioinformatics
    • Center Member
      Caswell Diabetes Institute

    Recent Publications

     See All Publications
    • Journal Article
      Sphingolipids and Mortality in Hemodialysis: Innocent Bystanders or Causal Culprits?
      Saum KL, Pennathur S. J Am Soc Nephrol, 2026 Apr 27; DOI:10.1681/ASN.0000001110
      PMID: 42043881
    • Journal Article
      Author Correction: Mitochondrial complex II in intestinal epithelial cells regulates T cell-mediated immunopathology.
      Fujiwara H, Seike K, Brooks MD, Mathew AV, Kovalenko I, Pal A, Lee H-J, Peltier D, Kim S, Liu C, Oravecz-Wilson K, Li L, Sun Y, Byun J, Maeda Y, Wicha MS, Saunders TL, Rehemtulla A, Lyssiotis CA, Pennathur S, Reddy P. Nat Immunol, 2026 Mar 24; DOI:10.1038/s41590-026-02504-8
      PMID: 41876720
    • Journal Article
      Associations between prenatal per- and polyfluoroalkyl substances (PFAS) and repeated measures of bioactive lipids during pregnancy in the LIFECODES cohort
      Siwakoti RC, Ferguson KK, Hao W, Cantonwine DE, Mukherjee B, Park SK, Zeng L, Pennathur S, McElrath TF, Meeker JD. Science of the Total Environment, 2026 Feb 15; 1016: DOI:10.1016/j.scitotenv.2026.181465
      PMID: 41610549
    • Journal Article
      Metabolic surgery mitigates early kidney injury in obese youth with diabetes by suppressing mTORC1/JAK-STAT signaling.
      Naik AS, Alakwaa FM, Nair V, McCown PJ, Schaub JA, Otto EA, Menon R, Annese F, Choi YJ, Hampson HE, Inge TH, Hartman J, Eddy S, Smith C, Hodgin JB, Inoki K, Srivastava SP, Al-Fagih K, Yoshida S, Goodrich JA, Cree MG, Narongkiatikhun P, Yuan L, Tommerdahl KL, Prasad P, van Raalte DH, Kelsey MM, Ryder JR, Dobbs TJ, Ladd P, Pennathur S, Nelson RG, Okabayashi Y, Puelles VG, Ferrence-Salo J, Beamish JA, Brosius FC, Nadeau KJ, Pyle L, Kretzler M, Bjornstad P. J Clin Invest, 2026 Feb 3; DOI:10.1172/JCI198545
      PMID: 41665972
    • Journal Article
      Chronic kidney disease induces distinct alterations of macrophage lipid metabolism in a mouse model of atherosclerosis
      Saum K, Liu X, Rajendiran T, Zeng L, Kayampilly P, Byun J, Afshinnia F, Pennathur S. Journal of Lipid Research, 2026 Feb 1; 67 (2): DOI:10.1016/j.jlr.2026.100975
      PMID: 41485713
    • Journal Article
      Dapagliflozin mitigates hypoxia-induced metabolic stress, kidney tubular cell death and fibrosis.
      Minakawa A, El Saghir J, Berthier CC, Lassé M, Maity S, Baek J, Fermin D, Billing A, He C, Eichinger F, Hartman J, Nair V, Fischer M, Vega-Warner V, Alakwaa F, Godfrey B, McCown PJ, Menon R, Demir F, Pennathur S, Sharma K, Schaub JA, Rinschen MM, Kretzler M, Harder JL. bioRxiv, 2026 Jan 14; DOI:10.64898/2025.12.13.693777
      PMID: PMC12724654
    • Preprint
      Accelerated osteocytic citrate production in chronic kidney disease is associated with protection of the kidney.
      Har JRG, Hsu MY-H, Saum KL, Singh A, Sriram R, Kuennen DP, Zhu EK, Pennathur S, Antoniewicz MR, Surface LE. 2025 Oct 9; DOI:10.1101/2025.10.08.681058
      PMID: 41279058
    • Proceeding / Abstract / Poster
      Artificial-Intelligence-Based Trajectory Clustering Analysis Identifies High-Risk and Previously Overlooked Patients with CKD
      Kanda E, Epureanu BI, Adachi T, Sasaki T, Pennathur S, Okada H, Nangaku M, Kashihara N. Journal of the American Society of Nephrology, 2025 Oct 24; 36 (10S): 10.1681/asn.2025jj6fzckf DOI:10.1681/asn.2025jj6fzckf