Michael Karsy
Neurosurgery
1200 E. Michigan Ave., Suite 340
Lansing, MI 48912
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About
I am a Clinical Assistant Professor of Neurosurgery at the University of Michigan. I completed my undergraduate degree with honors in Neuroscience at the University of California Los Angeles and a combined MD/PhD program at New York Medical College. I then completed residency in neurosurgery at the University of Utah under Dr. William Couldwell in 2020 with enfolded fellowship in Complex Spine Surgery with Dr. Andrew Dailey and Dr. Erica Bisson as well as a Masters of Bioengineering in Medical Device Development. I then completed a Skull Base fellowship at Thomas Jefferson University Hospital under Dr. James Evans in 2021.
I practice at both the University of Michigan Health – Sparrow and University of Michigan Health – Ann Arbor. My primary focus is on neuro-oncology and skull base pathologies with specialization in endoscopic and minimally invasive approaches. I works as part of a large multi-disciplinary team managing neuro-oncology issues (e.g., pituitary adenomas, meningiomas, gliomas, vestibular schwannomas, metastatic disease). I also have an interest in spine management (e.g., minimally invasive spine surgery, cervical myelopathy, spine tumors, trauma, deformity). My role also involves serving as the Director of Clinical Operations and Quality at University of Michigan Health – Sparrow and previously served as faculty at the University of Utah and Drexel University College of Medicine.
Links
Personal and lab website youtube Department website Google Scholar linkedin ResearchGate Twitter/X
Qualifications
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Fellowship in Skull BaseThomas Jefferson University Hospital, Neurosurgery, Philadelphia, USA
2020 - 2021
Clinical Fellowship
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Neurosurgical ResidencyUniversity of Utah Health Care, Neurosurgery, Salt Lake City, United States
2013 - 2020
Residency
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Fellowship in SpineUniversity of Utah Health Care, Neurosurgery, Salt Lake City, United States
2018 - 2019
Clinical Fellowship
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MScUniversity of Utah, Salt Lake City, United States
2016 - 2017
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MD/PhDNew York Medical College, Valhalla, United States
2006 - 2013
Research Overview
My research interests are in molecular characterization and targeted therapy of skull base pathologies, multi-institutional collaboration to advance skull base research, improving healthcare outcomes, and reducing surgical complications through improved integration of techniques and technology in neurosurgery. I have proudly worked on over 190 publications, 11 book chapters, and a surgical textbook. I have participated as a co-investigator and principal investigator on multiple clinical trials in neurosurgical trauma, critical care, and neuro-oncology. I enjoy working with medical students, residents, and fellows both locally and nationally in a variety of research endeavors. I am currently active in the North American Skull Base Society among areas of organized neurosurgery and serve on the research committee I also serve on steering committee member of Registry on Pituitary Adenomas and Related Disorders (RAPID) which is a multi-center consortium involved in clinical and translational research of skull base pathologies.
Recent Publications
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Demir E, Rahmanipour E, Ghorbani M, Gupta K, Zeinali M, Karsy M. Molecular Biology Reports, 2026 Dec 1; 53 (1):Journal ArticleNeutrophils in glioblastoma: orchestrators of the tumor microenvironment and immune evasion
DOI:10.1007/s11033-026-11525-3 PMID: 41632336 -
Damante MA, Juncker RB, Kim AH, Evans JJ, Barkhoudarian G, Fernandez-Miranda JC, Pacione DR, Kim W, Chicoine MR, Zada G, Kshettry VR, Benjamin C, Gompel JV, Catalino M, Mamelak A, Zwagerman N, Little AS, Pacult MA, Gardner P, Karsy M, Couldwell WT, Rennert RC, Palmer JD, Prevedello DM, Wu KC. Neurosurgical Focus, 2026 Jun 1; 60 (6):Journal ArticleComparison of clinical outcomes in adamantinomatous and papillary craniopharyngioma: a baseline analysis before the targeted therapy era
DOI:10.3171/2026.2.FOCUS251172 PMID: 42224722 -
Kelleher ST, Chen AY, Feng R, Collopy C, Rennert RC, Couldwell WT, Kshettry VR, Gardner P, Silverstein JM, Kim AH, Barkhoudarian G, Kelly D, Pacione DR, Suryadevara CM, Kim W, Bergsneider M, Chicoine MR, Zada G, Wu KC, Prevedello DM, Benjamin C, Catalino MP, Mamelak A, Cheok SK, Zwagerman NT, Van Gompel JJ, Palit SR, Fernandez-Miranda JC, Yuen KCJ, Little AS, Karsy M, Evans JJ. Neurosurgical Focus, 2026 Jun 1; 60 (6): E7Journal ArticleFrailty and postoperative outcomes following craniopharyngioma resection: a multicenter Registry for Adenomas of the Pituitary and Related Disorders analysis
DOI:10.3171/2026.2.FOCUS251160 PMID: 42224740 -
Tenhoeve SA, Tang A, Orton CJ, Gautam D, Abdul-Rahman NH, Silverstein JM, Kim AH, Evans JJ, Barkhoudarian G, Fernandez-Miranda JC, Pacione DR, Kim W, Bergsneider M, Chicoine MR, Zada G, Kshettry VR, Wu KC, Benjamin CG, Van Gompel J, Palit SR, Catalino MP, Mamelak AN, Zwagerman NT, Cheok SK, Little AS, Zenonos GA, Karsy M, Morshed RA, Blackburn SL, Mukherjee D, Beer-Furlan A, Couldwell WT, Gardner PA, Rennert RC. Neurosurgical Focus, 2026 Jun 1; 60 (6): E6Journal ArticlePredictors of hospital length of stay, discharge disposition, and readmission after craniopharyngioma surgery: a multicenter study from the RAPID database
DOI:10.3171/2026.2.FOCUS251047 PMID: 42224727 -
Freeman H, Baloi D, Rawson C, Kaur S, Pahlevani M, Karsy M. Biomedicine Hub, 2026 May 24; 1 - 17.Journal ArticleImmunotherapy in Metastatic Brain Tumors: Mechanisms, Challenges, and Opportunities for Neurosurgical Integration: A 10-Year Narrative Review
DOI:10.1159/000552630 -
Underhill HR, Sellers DL, Hellwig S, Baradaran H, Bronner MP, Thomas A, Menacho S, Davidson CJ, Malani R, Farrell A, Karsy M, Nix DA, Zhang Y, Boatz LA, Mendez J, Burt L, Cannon D, Dean CS, Harrison BE, Stevenson S, Aitken K, Pulst SM, Colman H, Jensen RL. NPJ Precis Oncol, 2026 May 22;Journal ArticleMolecular features unique to circulating tumor DNA enable the tumor-naïve liquid biopsy of glioblastoma.
DOI:10.1038/s41698-026-01496-w PMID: 42174019 -
Shinya Y, Palit SR, Peris Celda M, Little AS, Pacult MA, Gardner P, Zenonos G, Evans J, Fernandez-Miranda J, Mamelak A, Rennert RC, Couldwell WT, Zada G, Kim AH, Silverstein JM, Kim W, Bergsneider M, Wu KC, Prevedello DM, Zwagerman N, Cheok S, Catalino MP, Kshettry VR, Karsy M, Van Gompel JJ. J Neurosurg, 2026 May 1; 1 - 11.Journal ArticleAdamantinomatous craniopharyngioma: outcomes from a US multicenter registry cohort (RAPID consortium study).
DOI:10.3171/2025.12.JNS252065 PMID: 42066361 -
Rahmanipour E, Ghorbani M, Demir E, Gupta K, Sani GG, Patillo C, Pahlevani M, Baloi D, Samieirad S, Daskareh M, Karsy M. Critical Reviews in Oncology Hematology, 2026 May 1; 221:Journal ArticleEfficacy of intra-arterial chemotherapy across intracranial tumors: A systematic review and meta-analysis
DOI:10.1016/j.critrevonc.2026.105210 PMID: 41679522