
Clinical Assistant Professor of Radiation Oncology
Medical School
Radiation Oncology - Physics
1500 East Medical Center Drive
Ann Arbor, Mi 48103-5010
[email protected]
1500 East Medical Center Drive
Ann Arbor, Mi 48103-5010
Available to mentor
Karolyn Hopfensperger, PhD

Clinical Assistant Professor
Dr. Hopfensperger received her PhD in Biomedical Engineering at the University of Iowa. She completed her Therapeutic Medical Physics residency at Huntsman Cancer Institute at the University of Utah. She joined the Medical Physics faculty at Michigan Medicine in 2023.
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Therapeutic Medical Physics ResidencyHuntsman Cancer Institute, University of Utah, Salt Lake City, 2022
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PhDUniversity of Iowa, 2020
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BSUniversity of Wyoming, 2015
Areas of Interest:
Novel brachytherapy applicators and isotopes
Monte Carlo analysis
Out-of-field dose measurement
Clinical trials
Education and outreach
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Hopfensperger K, Li W, Sheldon S, Rotondo R, Chen R, St. James S, Lin Y. 2024 Jul 21;Proceeding / Abstract / PosterEstimates of Cardiac Implanted Electronic Device Dose for the Proteus One Proton Therapy System
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Flynn RT, Smith BR, Adams QE, Patwardhan K, Graves SA, Hopfensperger KM. Medical Physics, 2024 May 1; 51 (5): 3604 - 3618.Journal ArticleA re-activation model for <sup>169</sup>Yb intensity modulated brachytherapy sources accounting for spatiotemporal isotopic composition
DOI:10.1002/mp.17048 PMID: 38558460 -
Hopfensperger KM, Adams QE, Kim Y, Wu X, Xu W, Patwardhan K, Flynn RT. Medical Physics, 2023 Oct 1; 50 (10): 6469 - 6478.Journal ArticleThe population percentile allowance method for determining systematic spatial error tolerances for temporary intensity modulated brachytherapy
DOI:10.1002/mp.16668 PMID: 37643427 -
Hopfensperger KM, Li X, Paxton A, Sarkar V, Su FCF, Price RG, Salter B, St. James S. Journal of Applied Clinical Medical Physics, 2023 May 1; 24 (5):Journal ArticleMeasurements of fetal dose with Mevion S250i proton therapy system with HYPERSCAN
DOI:10.1002/acm2.13957 PMID: 37043346 -
Flynn R, Kim Y, Wu X, Hopfensperger K, Adams Q. 2023 Jan 3;PatentApparatus and method for rotating shield brachytherapy
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Hopfensperger K, Paxton A, Sarkar V, Su F-CF, Price R, Salter B, St. James S. 2022 Jul 10;Proceeding / Abstract / PosterEstimates of Fetal Dose with the Mevion S250i Proton Therapy System with HYPERSCAN
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Yi J, Adams QE, Hopfensperger KM, Flynn RT, Kim Y, Buatti JM, Xu W, Wu X. 2024 Mar 1;Journal ArticleOptimal Needle Placement for Prostate Rotating-Shield Brachytherapy (RSBT)
DOI:10.48550/arxiv.2110.07841 -
Hopfensperger K, Kunz J, Li X, Zhao H, Nelson G, Su F-CF, Stinnett G, Gaffney D, Burt L, Suneja G, Huang YJ. Brachytherapy, 2021 Jun 22; 20 (3):Proceeding / Abstract / PosterEffects of Interfractional Variations in MCVC Placement and Rotation on HR-CTV and OAR Dose
DOI:10.1016/j.brachy.2021.06.119