Stephanie Ann Smith, DVM, MS
Associate Research Scientist, Biological Chemistry, Medical School
Email:
[email protected]
Available to mentor
Stephanie Ann Smith, DVM, MS
Associate Research Scientist
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Research Overview
Basic science research primarily focused on the contributions of polyphosphate to hemostasis, thrombosis, and inflammation
Recent Publications
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Smith SA, Morrissey JH. Bleeding Thrombosis and Vascular Biology, 2026 Aug 28; 5 (3):Journal ArticleTrypsin is as procoagulant as factor XIIa
DOI:10.4081/btvb.2026.564 -
Ramesh Bhatt S, Ginsberg AG, Smith SA, Morrissey JH, Fogelson AL. Research and Practice in Thrombosis and Haemostasis, 2026 Aug 1; 10 (6):Journal ArticleModeling the role of platelet-released polyphosphates in tissue factor-initiated coagulation under flow
DOI:10.1016/j.rpth.2026.106930 -
Ramesh Bhatt S, Ginsberg A, Smith S, Morrissey J, Fogelson A. 2026 May 19; bioRxiv,PreprintModeling the Role of Platelet-Released Polyphosphates in Tissue-Factor-Initiated Coagulation under Flow
DOI:10.64898/2026.03.19.713007 -
Saleem M, Li C, Kaira BG, Brown AK, Pathak M, Najmudin S, Cowieson N, Dreveny I, Wilson C, Shamanaev A, Gailani D, Smith SA, Morrissey JH, Philippou H, Emsley J. Acta Crystallographica Section D Structural Biology, 2025 Jul 1; 81 (Pt 7): 380 - 393.Journal ArticleCrystal structure of coagulation factor XII N-terminal domains 1-5
DOI:10.1107/S2059798325005297 PMID: 40576968 -
La CC, Smith SA, Kalathottukaren MT, Haynes CA, Morrissey JH, Kizhakkedathu JN. Advanced Healthcare Materials, 2024 Aug 7; 13 (20):Journal ArticleExternal Trigger Free Charge Switchable Cationic Ligands in the Design of Safe and Effective Universal Heparin Antidote
DOI:10.1002/adhm.202400108 PMID: 38537246 -
Sedzro JC, Smith SA, Scott A, Wang Y, Travers RJ, Hemp R, Morse CN, Morrissey JH. Research and Practice in Thrombosis and Haemostasis, 2024 Aug 1; 8 (6):Journal ArticleAntipolyphosphate monoclonal antibodies derived from autoimmune mice
DOI:10.1016/j.rpth.2024.102550 -
Macarthur TA, Goswami J, Navarro SM, Vappala S, La CC, Yudin N, Zietlow J, Smith SA, Morrissey JH, Spears GM, Bailey KR, Dong JF, Kozar RA, Kizhakkedathu JN, Park MS. Shock, 2024 Jun 1; 61 (6): 848 - 854.Journal ArticleInhibitors of Inorganic Polyphosphate and Nucleic Acids Attenuate in Vitro Thrombin Generation in Plasma from Trauma Patients
DOI:10.1097/SHK.0000000000002362 PMID: 38662595 -
La CC, Smith SA, Vappala S, Adili R, Luke CE, Abbina S, Luo HD, Chafeeva I, Drayton M, Creagh LA, de Guadalupe Jaraquemada-Peláez M, Rhoads N, Kalathottukaren MT, Henke PK, Straus SK, Du C, Conway EM, Holinstat M, Haynes CA, Morrissey JH, Kizhakkedathu JN. Nature Communications, 2023 Dec 1; 14 (1):Journal ArticleSmart thrombosis inhibitors without bleeding side effects via charge tunable ligand design
DOI:10.1038/s41467-023-37709-0 PMID: 37100783
Featured News & Stories
Department News
Two Biological Chemistry faculty members receive promotions in 2026
U-M Biological Chemistry faculty members Angela Fleischhacker and Stephanie Smith have been promoted.
