Jordan Shavit, MD, PhD

Henry and Mala Dorfman Family Professor of Pediatric Hematology/Oncology

Professor of Pediatrics

Professor of Human Genetics

Medical School

Email:

[email protected]

Available to mentor

Jordan Shavit, MD, PhD

Professor

Qualifications

Center Memberships

Links

Recent Publications

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Qualifications

PhD
Northwestern University, Evanston, IL, United States
1994 - 2000

MD
Northwestern University Medical School, Evanston, IL, United States
1992 - 2000

Center Memberships

Center Member
Frankel Institute for Heart and Brain Health
Center Member
AI and Digital Health Innovation
Center Member
Center for Cell Plasticity and Organ Design
Center Member
Samuel and Jean Frankel Cardiovascular Center
Center Member
Rogel Cancer Center

Recent Publications

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Journal Article
Research agenda and related workforce requirements inspired by Lived Experience Experts and grounded in health equity for the Bleeding Disorders Research Collaborative
Johnsen JM, Buckner TW, Batsuli G, Carlson SA, Burke Cirelli E, DiMichele D, Flood VH, Johnson AD, Heiman M, Kaplan J, Konkle BA, Khor B, Lankau EW, Levy GG, Norris KL, Pierce GF, Popp NA, Recht M, Roberts JC, Robinson F, Santaella ME, Shavit JA, Stanhope RW, Valadez S, Witkop ML, Malec L, Shapiro AD. Expert Review of Hematology, 2026 Jul 1; 19: 63 - 79. DOI:10.1080/17474086.2026.2688867
PMID: 42563287
Journal Article
Impaired Cellular Trafficking of a Novel Thrombomodulin Mutant Causes Severe Bleeding, Thrombosis, and Atypical HUS
Gemel J, Barnawi Z, Dahlgren AR, Chang A, Hashmat S, Shavit JA, Lapping-Carr G, Beyer EC. Blood Vessels Thrombosis & Hemostasis, 2026 Jun 21; 100182 DOI:10.1016/j.bvth.2026.100182
Preprint
A sensitized model of thrombosis validates known multigenic relationships and suggests novel modifiers of hemostasis.
Grzegorski SJ, Liu Y, Richter CE, Yaman M, Vo AH, Yu X, Dahlgren AR, Madarati H, Friedmann AP, Surakka I, Kim PY, Kretz CA, Shavit JA. 2026 May 13; DOI:10.64898/2026.05.11.724445
PMID: 42182511
Journal Article
Deconstructing cardiovascular and coagulation-related traits links dietary ecology to multi-functional snake venom specificity
Holding ML, Pontius MHH, Ward MS, Akhtar J, Crowell HL, Svilar D, Keeler KM, Haynes LM, Ginsburg D, Shavit JA. Evolution, 2026 May 1; 80 (5): 1035 - 1046. DOI:10.1093/evolut/qpag036
PMID: 41811938
Journal Article
Small-molecule inhibition of γ-glutamyl carboxylase reveals a novel anticoagulant strategy
Shen G, Song D, Li S, Chen X, Richter CE, Dong S, Guo Y, Liu H, Shen Y, Hao Z, Stafford DW, Shavit JA, Cao Q, Tie JK. Blood Advances, 2026 Apr 14; 10 (7): 2363 - 2375. DOI:10.1182/bloodadvances.2025018776
PMID: 41428972
Journal Article
The Na/K-ATPase α1 subunit fine-tunes platelet P2Y12 function and mediates sex dimorphism-associated thrombosis.
Li OQ, Yue H, DeHart AR, Roytenberg R, Li AY, Bai F, Su H, Aguilar R, Olanipekun O, Liu J, Fedorova OV, Kennedy D, Thompson E, Shavit JA, Pierre SV, Li W. Blood Adv, 2026 Feb 24; 10 (4): 973 - 986. DOI:10.1182/bloodadvances.2025016605
PMID: 41733960
Journal Article
The Na/K-ATPase α1 subunit fine-tunes platelet P2Y12 function and mediates sex dimorphism–associated thrombosis
Li OQ, Yue H, DeHart AR, Roytenberg R, Li AY, Bai F, Su H, Aguilar R, Olanipekun O, Liu J, Fedorova OV, Kennedy D, Thompson E, Shavit JA, Pierre SV, Li W. Blood Advances, 2026 Feb 24; 10 (4): 973 - 986. DOI:10.1182/bloodadvances.2025016605
PMID: 41118620
Journal Article
ER-associated degradation pathway protein SEL1L plays an evolutionarily conserved role in platelet adhesion
Dahlgren AR, Careddu F, Norris JW, Di Buduo CA, Stanger L, Adili R, Kropp EM, Li Q, Holinstat M, Biunno I, Balduini A, Tablin F, Shavit JA, Finno CJ. Journal of Clinical Investigation, 2026 Feb 16; 136 (4): DOI:10.1172/JCI191433
PMID: 41697739