Henry and Mala Dorfman Family Professor of Pediatric Hematology/Oncology
Professor of Pediatrics
Professor of Human Genetics
[email protected]
Available to mentor
Jordan Shavit
Professor
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PhDNorthwestern University, Evanston, 2000
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MDNorthwestern University Medical School, Evanston, 2000
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Center MemberSamuel and Jean Frankel Cardiovascular Center
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Center MemberRogel Cancer Center
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Ku C-J, Yu X, Zhao QY, Grzegorski SJ, Daniel JG, Ferguson AC, Shavit JA. Blood Adv, 2024 Dec 10;Journal ArticleLoss of protein C vs protein S results in discrepant thrombotic phenotypes.
DOI:10.1182/bloodadvances.2024013237 PMID: 39657127 -
Augustin B, Wu D, Black LP, Bertrand A, Sulaiman D, Hopson C, Jacob V, Shavit JA, Hofmaenner DA, Labilloy G, Smith L, Cagmat E, Graim K, Datta S, Reddy ST, Guirgis FW. Crit Care, 2024 Dec 24; 28 (1): 431Journal ArticleMultiomic molecular patterns of lipid dysregulation in a subphenotype of sepsis with higher shock incidence and mortality.
DOI:10.1186/s13054-024-05216-3 PMID: 39716214 -
Yu X, Zhao QY, Yaman M, Emly SM, Lee JK, Su H, Ferguson AC, Nagaswami C, Chaturantabut S, Goessling W, Weisel JW, Auchus RJ, Shavit JA. 2024 Nov 15;PreprintHormone-induced thrombosis is mediated through non-canonical fibrin(ogen) aggregation and a novel estrogen target in zebrafish.
DOI:10.1101/2024.11.13.623199 PMID: 39605542 -
Griffin MS, Dahlgren AR, Nagaswami C, Litvinov RI, Keeler K, Madenjian C, Fuentes R, Fish RJ, Neerman-Arbez M, Holinstat M, Adili R, Weisel JW, Shavit JA. J Thromb Haemost, 2024 Apr; 22 (4): 1056 - 1068.Journal ArticleComposition of thrombi in zebrafish: similarities and distinctions with mammals.
DOI:10.1016/j.jtha.2023.12.025 PMID: 38160724 -
Pontius MHH, Ku C-J, Osmond MJ, Disharoon D, Liu Y, Warnock M, Lawrence DA, Marr DWM, Neeves KB, Shavit JA. Proc Natl Acad Sci U S A, 2024 Mar 5; 121 (10): e2315083121Journal ArticleMagnetically powered microwheel thrombolysis of occlusive thrombi in zebrafish.
DOI:10.1073/pnas.2315083121 PMID: 38408253 -
Richter CE, Raghunath A, Griffin MS, Yaman M, Arruda VR, Samelson-Jones BJ, Shavit JA. bioRxiv,PreprintLoss of factor VIII in zebrafish rebalances antithrombin deficiency but has a limited bleeding diathesis
DOI:10.1101/2024.02.28.582609 -
Xu Z, Jobe SM, Ma Y-Q, Shavit JA. J Thromb Haemost, 2024 Feb; 22 (2): 558 - 564.Journal ArticleA novel leukocyte adhesion deficiency type III mutation manifests functional importance of the compact FERM domain in kindlin-3.
DOI:10.1016/j.jtha.2023.10.013 PMID: 37866516 -
Kocere A, Chiavacci E, Soneson C, Wells HH, Méndez-Acevedo KM, MacGowan JS, Jacobson ST, Hiltabidle MS, Raghunath A, Shavit JA, Panáková D, Williams MLK, Robinson MD, Mosimann C, Burger A. bioRxiv, 2024 Feb 1;Journal ArticleRbm8a deficiency causes hematopoietic defects by modulating Wnt/PCP signaling.
DOI:10.1101/2023.04.12.536513 PMID: 37090609
Medical School News
Four with Medical School ties are among 12 University of Michigan faculty and staff members recognized by the American Association for the Advancement of Science (AAAS) as 2023 fellows in recognition of their extraordinary achievements.
Department News
Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.
