DCMB Tools & Technology Seminar: Sophia Luo

Name: DCMB Tools & Technology Seminar: Sophia Luo
Start: 2026-11-12T12:00:00
End: 2026-11-12T13:00:00

Tools & Technology Seminar Series Event Series

Date:

Thursday, November 12, 2026

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Time:

12:00 pm to 1:00 pm

Location:

Medical Science Building1 (MS1), Room 4B700

ZOOM

About This Event

Join us for the DCMB Tools & Technology Seminar Series featuring a presentation by Sophia Luo from the Department of Biostatistics. Enjoy a complimentary pizza lunch while learning about innovative research and cutting-edge tools.

“MethylModes: Intuitive Detection of Multimodal Distributions in DNA Methylation Data”

Tool Link: https://github.com/lutiffan/methylModes

Abstract

MethylModes is an R package and Shiny application to identify multimodal distributions in human DNA methylation at individual CpG sites. Multimodal distributions, which can be the result of nearby genetic variation, environmental exposures or assay artifacts, are susceptible to confounding and important to identify for methylation analysis. We developed MethylModes to robustly identify multimodality in beta value distributions using an intuitive algorithm that avoids stringent modeling assumptions. MethylModes is easily incorporated into existing quality control pipelines of array-based DNA methylation data.

Presenters

Sophia Luo

PhD Student (Biostatistics)

Host/Moderator

Marci Brandenburg

Librarian, Library - Health Sciences, University Library

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