Dr. John Varga Delivers Prestigious Philip Hench Memorial Lecture at ACR Convergence 2026

Dr. John Varga, Frederick G L Huetwell Research Professor of Rheumatology and division chief of Rheumatology, was selected to deliver the prestigious Philip Hench Memorial Lecture at American College of Rheumatology (ACR) Convergence 2026, recognizing his significant contributions to rheumatology research and advancing our understanding of fibrotic diseases. His lecture, titled “Fixing Fibrosis in Scleroderma: Does the Fibroblast Hold the Key?”, explored exciting new discoveries that could reshape how researchers approach fibrosis in scleroderma and other rheumatic diseases.

The Philip Hench Memorial Lecture is a distinguished honor that highlights important contributions to the field of rheumatology. Dr. Varga's recognition reflects his longstanding commitment to scientific discovery and his leadership in advancing research that may transform the future of treatment for patients living with fibrotic diseases.

Dr. Varga's presentation focused on the role of fibroblasts, specialized connective tissue cells that play a central role in tissue repair and scarring. In scleroderma, these cells can become persistently activated, producing excessive collagen and contributing to progressive tissue damage. His research explores how interactions between fibroblasts, immune cells, and cellular signaling pathways drive this process, as well as the possibility of reprogramming these cells to restore healthier tissue function.

An important theme of the lecture was the potential to move beyond simply slowing the progression of fibrosis toward finding ways to reverse established tissue scarring. Through innovative research investigating fibroblast biology, cellular metabolism, and primary cilia, Dr. Varga and his colleagues are uncovering new therapeutic possibilities that may ultimately benefit patients with scleroderma and a broad range of other fibrotic conditions.

Read more here.