The body employs an array of hormones to regulate internal temperature, metabolism, growth, and responses to stress and injury. Research within the U-M Medical School Department of Pharmacology investigates the mechanisms underlying:
- The biogenesis of trafficking organelles and the synthesis, storage and secretion of hormones from the adrenal medulla and endocrine pancreas.
- Steroid biosynthesis, with an emphasis on the mechanistic enzymology of steroidogenic cytochrome P450s and dehydrogenases/reductases. The translational application of this research leverages our expertise in steroid mass spectrometry and use of multi-steroid panels to profile steroid hormones, precursors and metabolite in a single assay.
- Pulsatile insulin secretion from pancreatic islets and stimulus secretion coupling in pancreatic beta cell, with an emphasis on dysfunctional secretion in type 1 and type 2 diabetes.
Pfizer Upjohn Early Career Research Professor of Molecular Pharmacology
Assistant Professor of Pharmacology
Assistant Professor of Internal Medicine
Assistant Professor of Pharmacology
Assistant Professor of Internal Medicine
Professor of Pharmacology
Assistant Professor of Pharmacology
F Blicke Collegiate Professor of Pharmacy
Professor of Medicinal Chemistry
College of Pharmacy
Professor of Pharmacology
Professor of Biophysics
College of Literature, Science, and the Arts
Professor of Medicinal Chemistry
College of Pharmacy
Professor of Pharmacology
Professor of Biophysics
College of Literature, Science, and the Arts
James A Shayman and Andrea S Kevrick Professor of Translational Medicine
Professor of Internal Medicine
Professor of Pharmacology
Professor of Internal Medicine
Professor of Pharmacology
Professor of Pharmacology
