Srijan Sen

Srijan Sen
Frances and Kenneth Eisenberg Professor of Depression and Neurosciences
Center Director
University of Michigan Depression Center
Professor of Psychiatry and Research Professor
Michigan Neuroscience Institute
Medical School
[email protected]
Available to mentor
Srijan Sen
Srijan Sen
Center Director
  • About
  • Center Memberships
  • Recent Publications
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  • About

    Srijan Sen is the Frances and Kenneth Eisenberg Professor of Depression and Neurosciences and Director of the Eisenberg Family Depression Center at the University of Michigan. He received his M.D. and Ph.D. from the University of Michigan, completed a psychiatry residency at Yale University and returned to Michigan as faculty in 2009. The Intern Health Study is a longitudinal cohort study that assesses stress and mood in training physicians, enrolling over 25,000 participants from 100+ institutions. The project has produced high-impact findings across a wide range of interdisciplinary academic topics including genomics, mobile technology, economics, gender and racial disparities, survey methodology and medical education policy. Work from the study has been published in JAMA, BMJ, New England Journal of Medicine and other leading journals covered in the New York Times, Washington Post, Time Magazine and other media outlets. Dr. Sen is a member of the National Academy of Medicine Collaborative on Clinician Well-Being.

    Center Memberships

    • Center Member
      Center for Computational Medicine and Bioinformatics
    • Center Member
      Eisenberg Family Depression Center
    • Center Member
      Global REACH
    • Center Member
      Institute for Healthcare Policy and Innovation
    • Center Member
      AI and Digital Health Innovation
    • Center Member
      MM-PKUHSC Joint Institute
    • Center Member
      Taubman Institute

    Recent Publications

    See All Publications
    • Journal Article
      Testing bidirectional associations of major depressive disorder with medical conditions: two-sample Mendelian randomization study
      Fang Y, Sen S, Pathak GA, Burmeister M, Richmond-Rakerd LS. Npj Mental Health Research, 2026 Dec 1; 5 (1): DOI:10.1038/s44184-026-00204-7
    • Journal Article
      0358 Seasonal Rhythms in Wearable-Derived Sleep Across U.S. Latitudes
      Ross K, Pereira-Lima K, Shedden K, Sen S. Sleep, 2026 May 10; 49 (Supplement_1): a159 - a159. DOI:10.1093/sleep/zsag091.0358
    • Journal Article
      Understanding the impact of perceived app usability on the efficacy of mobile health intervention for traumatic brain injury caregivers.
      Wang J, Wu Z, Sander AM, Sen S, Choi SW, Miner JA, Graves C, Carlozzi NE. Rehabil Psychol, 2026 May 4; DOI:10.1037/rep0000674
      PMID: PMC13143335
    • Preprint
      Third places visits and well-being: insights from longitudinal passive sensing data
      Fang Y, Saulnier K, Cleary J, Wu Z, Bohnert ASB, Sen S. 2026 Mar 15; medRxiv, DOI:10.64898/2026.03.12.26348188
    • Preprint
      Personalized Insights Derived from Wearable Device Data and Large Language Models to Improve Well-Being
      He K, Fang Y, Frank E, Li C, Bohnert A, Sen S, Wang M. 2026 Mar 6; medRxiv, DOI:10.64898/2026.03.03.26347299
    • Journal Article
      Sleep, Physical Activity, and Mood Among People Seeking Mental Health Care.
      Kulshreshtha A, Fang Y, Mills ED, Bohnert ASB, Sen S. JAMA Netw Open, 2026 Mar 2; 9 (3): e261194 DOI:10.1001/jamanetworkopen.2026.1194
      PMID: PMC12973096
    • Journal Article
      Low-burden preventative digital mental health interventions for first-year college students: A pilot feasibility microrandomized trial
      Horwitz A, Anand S, Chen M, McCarthy K, Schueller SM, Walton M, Sen S, King CA. Internet Interventions, 2026 Jan 29; 43: 100912 - 100912. DOI:10.1016/j.invent.2026.100912
    • Journal Article
      Patterns of Smartphone Typing Performance by Time Awake in US Training Physicians: Implications for Unobtrusive Ambulatory Mental Fatigue Assessment
      Fang Y, Yang P, Frank E, Goldstein C, Wright AGC, Bohnert ASB, Kheterpal V, Sen S, Wu Z. 2025 Jun 26;

    Featured News & Stories

    Kenneth Eisenberg and the late Frances Eisenberg
    News Release

    $40 million gift supports Michigan Medicine’s new specialty care facility in Troy and mental health research

    A $40 million gift to Michigan Medicine from the Eisenberg Foundation will be honored with the naming of a center for specialty care that will be built in Troy, and will support depression prevention research.
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    From ‘trial and error’ to targeted precision: $17.9M grant accelerates U-M mental health research

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    Department News

    From ‘trial and error’ to targeted precision: $17.9M grant accelerates U-M mental health research

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