Alexander T Janke, MD, MHS
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About
As an emergency medicine physician and health services researcher, I am working to make emergency care safer, high-quality, and lower cost in the U.S. I aim to apply a learning health systems approach, enabled by data science and artificial intelligence, to improve diagnosis in the emergency care setting. My prior work has explored the role of emergency departments in the broader healthcare system, the evolution of acute care utilization patterns over time, and diagnostic quality and value.
Administrative Contact:
Denise Wieck
[email protected]
Qualifications
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Master of Science (MSc), Health and Healthcare ResearchUniversity of Michigan, Ann Arbor, United States
2022 - 2024
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Master of Health Science (MHS), Economics with Distinction & Minor in MathematicsYale School of Medicine, New Haven, CT, United States
2019 - 2022
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Doctor of Medicine (MD), Economics with Distinction & Minor in MathematicsWayne State University School of Medicine, Detroit, MI, United States
2013 - 2017
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Bachelor of Science (BS), Economics with Distinction & Minor in MathematicsUniversity of Michigan, Ann Arbor, MI, United States
2008 - 2012
Center Memberships
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Center MemberInstitute for Healthcare Policy and Innovation
Research Overview
My research focuses on diagnostic excellence in emergency medicine, with particular attention to how clinicians and systems manage diagnostic uncertainty in time-sensitive conditions such as pulmonary embolism, acute neurologic presentations, and pediatric abdominal pain. I also study the structural drivers of emergency care quality and value, including emergency department boarding, hospital capacity constraints, and the policy and financing environment in which acute care is delivered. Across these areas, I use national claims data, statewide clinical registries (including the Michigan Emergency Department Improvement Collaborative), and electronic health record data to characterize variation in care and to develop measures and interventions that improve quality at scale.
Recent Publications
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Janke AT, Wu D, Stubblefield WB, Westafer LM, Schmitzberger FF, Rodman A, Kocher KE, Haimovich AD. 2026 Jun 7; JMIR Preprints,PreprintLarge Language Model-Based Virtual Patients to Probe Emergency Medicine Clinician Decision-Making About Pulmonary Embolism Testing: A Multisite Pilot Study (Preprint)
DOI:10.2196/preprints.103522 -
Friedman AB, Delgado MK, Janke AT. Annals of Emergency Medicine, 2026 Jun 1; 87 (6): 694 - 696.Journal ArticleA Dose of Delay: Emergency Department Boarding and Early Clinical Deterioration
DOI:10.1016/j.annemergmed.2026.04.021 PMID: 42167816 -
Greco JA, Nypaver MM, Kocher KE, Macy ML, Janke AT, Seiler K, Sikavitsas A, Arora R, Mangus CW. Pediatrics, 2026 May 1; 157 (5):Journal ArticleImproving Pediatric Respiratory Chest Radiograph Stewardship in a Statewide Network.
DOI:10.1542/peds.2024-070583 PMID: 41942131 -
Schmitzberger F, Janke A. 2026 Apr 8;PresentationAutonomous Abstraction for Cardiac Arrest Registries
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Kocher KE, Janke AT, Hassett KP, Pizzo CA, Vashi AA, Thompson MP. Journal of General Internal Medicine, 2026 Jan 1;Journal ArticleVariation and Drivers of Spending Within 30-Day Emergency Department-Based Episodes of Care
DOI:10.1007/s11606-026-10173-4 PMID: 41670880 -
Gettel CJ, Kitchen C, Rothenberg C, Song Y, Koski-Vacirca R, Schaffer K, Janke AT, Mohr NM, Greenwood-Ericksen M, Venkatesh AK. BMC Health Services Research, 2025 Dec 1; 25 (1):Journal ArticleEmergency department visits among rural and urban older adults: disparities in ambulatory and emergency care sensitive conditions
DOI:10.1186/s12913-025-13161-2 -
Haimovich AD, Janke AT, Kocher KE, Mangus CW, Parsons AS, McCoy L, Taylor RA, Rodman A, Pusic M. Ann Emerg Med, 2025 Oct 9;Journal ArticleManaging Clinical Uncertainty: Formalizing Management Reasoning in Emergency Care Delivery.
DOI:10.1016/j.annemergmed.2025.09.007 PMID: 41071138 -
Marks C, Gibney S, Stenson B, Sarma D, Gaudet C, Mombini H, Buckley T, Burke L, Shapiro NI, Burstein JL, Grossman SA, Parab A, Janke AT, Manrai A, Taylor RA, Rosen CL, Rodman A, Haimovich AD. 2025 Oct 9; medRxiv,PreprintScalable screening for emergency department missed opportunities for diagnosis using sequential eTriggers and large language models
DOI:10.1101/2025.10.06.25337201
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