Alexander T Janke, MD, MHS

Alexander T. Janke
Assistant Professor of Emergency Medicine
Medical School
[email protected]
Available to mentor
Alexander T Janke, MD, MHS
Alexander T. Janke
Assistant Professor
  • About
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • Manage Your Profile

  • About

    As an emergency medicine physician and health services researcher, I am working to make emergency care safer, high-quality, and lower cost in the U.S. I aim to apply a learning health systems approach, enabled by data science and artificial intelligence, to improve diagnosis in the emergency care setting. My prior work has explored the role of emergency departments in the broader healthcare system, the evolution of acute care utilization patterns over time, and diagnostic quality and value.

    Administrative Contact:
    Denise Wieck
    [email protected]

    Qualifications

    • Master of Science (MSc), Health and Healthcare Research
      University of Michigan, Ann Arbor, United States
      2022 - 2024
    • Master of Health Science (MHS), Economics with Distinction & Minor in Mathematics
      Yale School of Medicine, New Haven, CT, United States
      2019 - 2022
    • Doctor of Medicine (MD), Economics with Distinction & Minor in Mathematics
      Wayne State University School of Medicine, Detroit, MI, United States
      2013 - 2017
    • Bachelor of Science (BS), Economics with Distinction & Minor in Mathematics
      University of Michigan, Ann Arbor, MI, United States
      2008 - 2012

    Center Memberships

    • Center Member
      Institute for Healthcare Policy and Innovation

    Research Overview

    My research focuses on diagnostic excellence in emergency medicine, with particular attention to how clinicians and systems manage diagnostic uncertainty in time-sensitive conditions such as pulmonary embolism, acute neurologic presentations, and pediatric abdominal pain. I also study the structural drivers of emergency care quality and value, including emergency department boarding, hospital capacity constraints, and the policy and financing environment in which acute care is delivered. Across these areas, I use national claims data, statewide clinical registries (including the Michigan Emergency Department Improvement Collaborative), and electronic health record data to characterize variation in care and to develop measures and interventions that improve quality at scale.

    Recent Publications

    See All Publications
    • Preprint
      Large Language Model-Based Virtual Patients to Probe Emergency Medicine Clinician Decision-Making About Pulmonary Embolism Testing: A Multisite Pilot Study (Preprint)
      Janke AT, Wu D, Stubblefield WB, Westafer LM, Schmitzberger FF, Rodman A, Kocher KE, Haimovich AD. 2026 Jun 7; JMIR Preprints, DOI:10.2196/preprints.103522
    • Journal Article
      A Dose of Delay: Emergency Department Boarding and Early Clinical Deterioration
      Friedman AB, Delgado MK, Janke AT. Annals of Emergency Medicine, 2026 Jun 1; 87 (6): 694 - 696. DOI:10.1016/j.annemergmed.2026.04.021
      PMID: 42167816
    • Journal Article
      Improving Pediatric Respiratory Chest Radiograph Stewardship in a Statewide Network.
      Greco JA, Nypaver MM, Kocher KE, Macy ML, Janke AT, Seiler K, Sikavitsas A, Arora R, Mangus CW. Pediatrics, 2026 May 1; 157 (5): DOI:10.1542/peds.2024-070583
      PMID: 41942131
    • Presentation
      Autonomous Abstraction for Cardiac Arrest Registries
      Schmitzberger F, Janke A. 2026 Apr 8;
    • Journal Article
      Variation and Drivers of Spending Within 30-Day Emergency Department-Based Episodes of Care
      Kocher KE, Janke AT, Hassett KP, Pizzo CA, Vashi AA, Thompson MP. Journal of General Internal Medicine, 2026 Jan 1; DOI:10.1007/s11606-026-10173-4
      PMID: 41670880
    • Journal Article
      Emergency department visits among rural and urban older adults: disparities in ambulatory and emergency care sensitive conditions
      Gettel CJ, Kitchen C, Rothenberg C, Song Y, Koski-Vacirca R, Schaffer K, Janke AT, Mohr NM, Greenwood-Ericksen M, Venkatesh AK. BMC Health Services Research, 2025 Dec 1; 25 (1): DOI:10.1186/s12913-025-13161-2
    • Journal Article
      Managing Clinical Uncertainty: Formalizing Management Reasoning in Emergency Care Delivery.
      Haimovich AD, Janke AT, Kocher KE, Mangus CW, Parsons AS, McCoy L, Taylor RA, Rodman A, Pusic M. Ann Emerg Med, 2025 Oct 9; DOI:10.1016/j.annemergmed.2025.09.007
      PMID: 41071138
    • Preprint
      Scalable screening for emergency department missed opportunities for diagnosis using sequential eTriggers and large language models
      Marks C, Gibney S, Stenson B, Sarma D, Gaudet C, Mombini H, Buckley T, Burke L, Shapiro NI, Burstein JL, Grossman SA, Parab A, Janke AT, Manrai A, Taylor RA, Rosen CL, Rodman A, Haimovich AD. 2025 Oct 9; medRxiv, DOI:10.1101/2025.10.06.25337201

    Featured News & Stories

    woman looking at screen in office clinical area
    Health Lab

    How AI is helping emergency physicians learn from their patients

    How the “Tell Me What Happens Next” initiative is being used by the Department of Emergency Medicine’s new Division of Clinical Informatics using artificial intelligence.
    man in hospital bed through curtains that are off orange beige
    Health Lab

    Wait times for emergency hospitalization keep getting higher

    Emergency department boarding of admitted patients to hospital beds has risen steadily and peaks in winter months.
    A PA talks into her phone, using DAX AI
    Department News

    The future, fast: Emergency Medicine at U-M positions AI as a department-wide strategy

    Artificial intelligence is transforming medicine nationwide — and at the University of Michigan, the Department of Emergency Medicine is moving faster and thinking bigger. Rather than using AI as a one-off tool, the department is adopting it as a core strategy — reshaping everything from education and clinical decision-making to operations, discovery and diagnostics. It’s a vision that places emergency medicine at the forefront of AI’s role in redefining academic medicine.