Associate Professor of Human Genetics
Associate Chair, Department of Human Genetics
Program Director, Human Genetics
Associate Professor of Obstetrics and Gynecology
Associate Professor of Urology
[email protected]
Available to mentor
Jacob L Mueller
Associate Professor
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Center MemberCenter for Cell Plasticity and Organ Design
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Swanepoel CM, Mueller JL. Semin Cell Dev Biol, 2024 163: 14 - 21.Journal ArticleOut with the old, in with the new: Meiotic driving of sex chromosome evolution.
DOI:10.1016/j.semcdb.2024.04.004 PMID: 38664120 -
Arlt MF, Kruger AN, Swanepoel CM, Mueller JL. bioRxiv, 2024 Oct 22;Journal ArticleReenacting a mouse genetic evolutionary arms race in yeast reveals SLXL1/SLX compete with SLY1/2 for binding to Spindlins.
DOI:10.1101/2024.10.18.619120 PMID: 39484540 -
Alektiar JM, Shan M, Radyk MD, Zhang L, Halbrook CJ, Lin L, Espinoza C, Mier IF, Lavoie BL, Salvatore L, Pasca di Magliano M, Cantley LC, Mueller JL, Lyssiotis CA. PLoS One, 2024 19 (6): e0303577Journal ArticleMalic enzyme 1 knockout has no deleterious phenotype and is favored in the male germline under standard laboratory conditions.
DOI:10.1371/journal.pone.0303577 PMID: 38843233 -
Stark-Dykema ER, Dulka EA, Gerlinger ER, Mueller JL. Sci Rep, 2022 May 20; 12 (1): 8554Journal ArticleX-linked palindromic gene families 4930567H17Rik and Mageb5 are dispensable for male mouse fertility.
DOI:10.1038/s41598-022-12433-9 PMID: 35595785 -
Stark-Dykema ER, Dulka EA, Gerlinger ER, Mueller JL. bioRxiv,PreprintX-linked palindromic gene families 4930567H17Rik and Mageb5 are dispensable for male mouse fertility
DOI:10.1101/2021.11.10.468145 -
Kruger AN, Mueller JL. Cell Mol Life Sci, 2021 Apr; 78 (7): 3205 - 3218.Journal ArticleMechanisms of meiotic drive in symmetric and asymmetric meiosis.
DOI:10.1007/s00018-020-03735-0 PMID: 33449147 -
Swanepoel CM, Gerlinger ER, Mueller JL. Mol Biol Evol, 2020 Jul 1; 37 (7): 1979 - 1985.Journal ArticleLarge X-Linked Palindromes Undergo Arm-to-Arm Gene Conversion across Mus Lineages.
DOI:10.1093/molbev/msaa059 PMID: 32145018 -
Baiz MD, Tucker PK, Mueller JL, Cortés-Ortiz L. J Hered, 2020 Sep 30; 111 (5): 419 - 428.Journal ArticleX-Linked Signature of Reproductive Isolation in Humans is Mirrored in a Howler Monkey Hybrid Zone.
DOI:10.1093/jhered/esaa021 PMID: 32725191
Department News
Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.
Department News
This summer, a group of local 4th and 5th grade students made a visit to the Department of Human Genetics to meet scientists and get hands-on experience with genetics. Their visit was coordinated by Dr. Diane Robins and Dr. Cristen Willer.