Gary D Luker, MD
Reed Dunnick Research Professor of Radiology
Associate Chair
Radiology Clinical Research
Professor of Biomedical Engineering
Medical School
University of Michigan
Radiology
109 Zina Pitcher Place, BSRB A710
Ann Arbor, MI 48109-2200
[email protected]
Radiology
109 Zina Pitcher Place, BSRB A710
Ann Arbor, MI 48109-2200
Available to mentor
Gary D Luker, MD
Professor
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About
I am a physician-scientist whose research centers at the interface of cancer biology and molecular imaging. I serve as the Editor of the RSNA journal, Radiology: Imaging Cancer.
Links
Lab website
Qualifications
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Research FellowshipWashington University in St. Louis School of Medicine, Laboratory of Molecular Radiopharmacology, St Louis, United States
1996 - 2002
Postdoctoral Fellowship
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FellowshipMallinckrodt Institute of Radiology, Pediatric Radiology, St. Louis, United States
1995 - 1996
Postdoctoral Fellowship
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ResidencyWashington University in St. Louis School of Medicine, Diagnostic Radiology, St Louis, United States
1991 - 1995
Residency
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MDWashington University School of Medicine, St Louis, MO, United States
1987 - 1991
Center Memberships
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Center MemberRogel Cancer Center
Research Overview
The Luker Lab investigates tumor-stromal interactions in cancer that drive tumor growth, metastasis, and drug resistance. The lab applies multi-scale imaging methods to understand tumor heterogeneity and predict early responses to therapy in models ranging from single cells to clinical studies.
Recent Publications
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Viola H, Carter H, Griffin K, Costa RM, McDonald R, Callow B, Gonzalez de Los Santos F, Panovich P, Carey S, Martinez M, Chen R, Hunter Z, Piotrowski-Daspit A, Luker G, Moore BB, Shea L. Biomaterials, 2026 Dec 1; 335:Journal ArticleAntifibrotic monocyte activation by nanoparticles resolves murine pulmonary fibrosis
DOI:10.1016/j.biomaterials.2026.124388 -
Huang C, Srivastava S, Ho KKY, Luker KE, Luker GD, Huan X, Garikipati K. Computer Methods in Applied Mechanics and Engineering, 2026 Aug 15; 458:Journal ArticleFP-IRL: Fokker–Planck inverse reinforcement learning — A physics-constrained approach to Markov decision processes
DOI:10.1016/j.cma.2026.119010 -
Fuller BT, Jones TH, Chan ET, D'Souza MW, Luker KE, Luker GD, Song JW. Anal Chem, 2026 Jun 21;Journal ArticleQuantitative Spatiotemporal Analysis of Intracellular Kinase Activity in Metastatic Breast Cancer Cells Using a Microfluidic-Based Lateral Diffusion Assay.
DOI:10.1021/acs.analchem.6c01060 PMID: 42323805 -
Klein JS, Luker GD. Radiology: Imaging Cancer, 2026 Mar 27; 8 (2):Journal Article2025 Manuscript Reviewers: A Note of Thanks
DOI:10.1148/rycan.260186 -
Luker GD. Radiology: Imaging Cancer, 2026 Mar 27; 8 (2):Journal ArticleEditor’s Recognition Awards
DOI:10.1148/rycan.260187 -
Malyarenko D, Ross BD, Peeters JM, Devaraj A, Jafari R, Tariq H, Pettit KM, Talpaz M, Luker GD, Chenevert TL. Magnetic Resonance in Medicine, 2026 Jan 1;Journal ArticleOn-Scanner Correction of Gradient Nonlinearity Bias for Accurate Assessment of Diffusion Heterogeneity Across Bone Sites in Myelofibrosis Patients
DOI:10.1002/mrm.70273 PMID: 41612146 -
Ciavattone NG, Bevoor A, Farfel A, Rehman A, Ho KKY, Rock EC, Chen Y-C, Luker KE, Humphries BA, Luker GD. Sci Rep, 2025 Feb 12; 15 (1): 5204Journal ArticleInhibiting CXCR4 reduces immunosuppressive effects of myeloid cells in breast cancer immunotherapy.
DOI:10.1038/s41598-025-89882-5 PMID: PMC11822021 -
Ross B, Malyarenko1 D, Luker G, Kandarpa M, Polk A, Pettit K, Talpaz M, Chenevert T. 2025 Dec 9;Proceeding / Abstract / PosterMRI detection of early changes in bone marrow fat content of ruxolitinib treated MF patients provides new insights into standard therapy response criteria
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