MeiLan K Han MD, MS
Pulmonary & Critical Care Medicine
1150 West Medical Center Drive, 6220C MSRB III
Ann Arbor, MI 48109
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About
MeiLan Han, MD MS, is a Professor of Medicine and Chief of the Division of Pulmonary and Critical Care at the University of Michigan Health. Dr. Han received her medical degree from the University of Washington in Seattle, WA. She completed her residency in Internal Medicine and fellowship in Pulmonary and Critical Care Medicine at the University of Michigan. Dr. Han has also completed a Master's Degree program in Biostatistics and Clinical Study Design at the University of Michigan School of Public Health.
Dr. Han’s research has focused on defining phenotypes in COPD using imaging. She is a lead investigator for several NIH sponsored COPD studies. She also serves as a spokesperson for the American Lung Association and on the board for the COPD Foundation. She is currently a Deputy Editor for the American Journal of Respiratory and Critical Care Medicine and serves as a member of the Global Obstructive Lung Disease scientific committee which is charged with developing internationally an internationally recognized consensus statement on COPD diagnosis and management. She is also the author of a book on lung health for the lay public, Breathing Lessons.
Links
http://drmeilanhan.com/ Breathing Lessons twitter linkedin instagram facebook
Center Memberships
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Center MemberAI and Digital Health Innovation
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Center MemberWeil Institute for Critical Care Research
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Center MemberTaubman Institute
Research Overview
Dr. Han’s research focuses on understanding patient heterogeneity to define disease subtypes in chronic obstructive pulmonary disease (COPD). In particular, Dr. Han has expertise in thoracic CT imaging with a particular focus on better understanding early disease and diversity in the pathways towards disease progression. Working with colleagues at the University of Michigan, Dr. Han has helped to validate the application of a dynamic image registration technique (Parametric Response Mapping) to thoracic CT scans in COPD. She is the University of Michigan Principal Investigator for both the SPIROMICS and COPDGene studies which are NIH funded cohort studies in COPD.
Recent Publications
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Singh D, Stacey R, Halpin DMG, Bhatt SP, Crawford J, Drury T, Di Boscio V, Kolterer S, Han MK. Am J Respir Crit Care Med, 2026 Jun 11;Journal ArticleDefining disease stability in COPD: Evidence from Phase 3 clinical trials.
DOI:10.1093/ajrccm/aamag292 PMID: 42281286 -
Fortis S, Gerard SE, Strand M, Motahari A, Bhatt SP, Han MK, Crapo JD, Silverman EK, Reinhardt JM, Hoffman EA, Comellas AP. Ann Am Thorac Soc, 2026 Jun 8;Journal ArticleAssociation of "Emptying Emphysema" with Clinical and Radiographic Features in People with Smoking History.
DOI:10.1093/annalsats/aaoag151 PMID: 42261268 -
Han MK, Stacey R, Halpin DMG, Bhatt SP, Crawford J, Di Boscio V, Singh D. American Journal of Respiratory and Critical Care Medicine, 2026 Jun 24; 212 (Supplement_2): aamag286.113Journal ArticleA16-10 Defining Disease Stability in COPD: A Post-Hoc Analysis of the Phase III IMPACT Trial
DOI:10.1093/ajrccm/aamag286.113 -
Hurst JR, Kaplan A, van Boven JFM, Bhutani M, Han MLK, Paulino E, Russell REK, Sawyer M, Trudzinski FC, van Ravenzwaay B, Winders T, Yorgancioglu A. European Respiratory Journal, 2026 Jun 1; 67 (6):Journal ArticleEnsuring continued access to essential inhaled respiratory medications: a call to action from the Inhaled Respiratory medicine Innovation and environmental Sustainability (IRIS) group
DOI:10.1183/13993003.01873-2025 PMID: 42242746 -
Wang JM, Pugashetti JV, Murray S, Mohan N, Kang E, Kazerooni E, Flaherty KR, Belloli E, Sheth JS, O’Dwyer DN, Han MK, Hatt CR, Oldham J. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.2203Journal ArticleA15-05 Screening for Interstitial Lung Disease Using Quantitative CT Thresholds
DOI:10.1093/ajrccm/aamag162.2203 -
Aoyama BC, Collaco JM, Mcgrath-Morrow SA, Curtis JL, Barjaktarevic I, Bosma C, Cooper CB, Hansel NN, Han MK, Hoffman EA, Paine R, Putcha N, Smith BM, Martinez FJ, Woodruff P, Neptune ER, Fawzy A, Raju S. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.1585Journal ArticleA16-01 The Respiratory Effects Of Prematurity Extend Over The Lifespan: Analyses From The SPIROMICS And SOURCE Studies
DOI:10.1093/ajrccm/aamag162.1585 -
Ram S, Oyer JM, Ng AS, Labaki WW, Bosma C, Curtis JL, Kazerooni EA, Hatt CR, Paine R, Soni AV, Ritchie AI, Wedzicha JA, Bateman LA, Hoffman EA, Martinez FJ, Galban CJ, Han MK, Investigators SAS. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.1588Journal ArticleA16-04 Significance of Mucus Plugs in Early COPD: An Analysis of the SOURCE Cohort
DOI:10.1093/ajrccm/aamag162.1588 -
Hermann EA, Hoffman EA, Angelini E, Barjaktarevic I, Bon J, Comellas AP, Cooper CB, Couper D, Curtis JL, Criner GJ, Wells M, Paine R, Krishnan JA, Labaki WW, Laine A, Lynch DA, Han MK, Hansel NN, Martinez FJ, Smith BM, Sun Y, Woodruff P, Barr RG. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.1595Journal ArticleA20-01 One-year Progression in Quantitative CT Parameters Predicts Subsequent Lung Function Decline Over 5 Years: The Subpopulations and Intermediate Outcome Measures in COPD Study (Spiromics)
DOI:10.1093/ajrccm/aamag162.1595
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