MeiLan K Han MD, MS
Pulmonary & Critical Care Medicine
1150 West Medical Center Drive, 6220C MSRB III
Ann Arbor, MI 48109
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About
MeiLan Han, MD MS, is a Professor of Medicine and Chief of the Division of Pulmonary and Critical Care at the University of Michigan Health. Dr. Han received her medical degree from the University of Washington in Seattle, WA. She completed her residency in Internal Medicine and fellowship in Pulmonary and Critical Care Medicine at the University of Michigan. Dr. Han has also completed a Master's Degree program in Biostatistics and Clinical Study Design at the University of Michigan School of Public Health.
Dr. Han’s research has focused on defining phenotypes in COPD using imaging. She is a lead investigator for several NIH sponsored COPD studies. She also serves as a spokesperson for the American Lung Association and on the board for the COPD Foundation. She is currently a Deputy Editor for the American Journal of Respiratory and Critical Care Medicine and serves as a member of the Global Obstructive Lung Disease scientific committee which is charged with developing internationally an internationally recognized consensus statement on COPD diagnosis and management. She is also the author of a book on lung health for the lay public, Breathing Lessons.
Links
http://drmeilanhan.com/ Breathing Lessons twitter linkedin instagram facebook
Center Memberships
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Center MemberRogel Cancer Center
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Center MemberAI and Digital Health Innovation
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Center MemberWeil Institute for Critical Care Research
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Center MemberTaubman Institute
Research Overview
Dr. Han’s research focuses on understanding patient heterogeneity to define disease subtypes in chronic obstructive pulmonary disease (COPD). In particular, Dr. Han has expertise in thoracic CT imaging with a particular focus on better understanding early disease and diversity in the pathways towards disease progression. Working with colleagues at the University of Michigan, Dr. Han has helped to validate the application of a dynamic image registration technique (Parametric Response Mapping) to thoracic CT scans in COPD. She is the University of Michigan Principal Investigator for both the SPIROMICS and COPDGene studies which are NIH funded cohort studies in COPD.
Recent Publications
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Han MK, Rabe KF, Sciurba FC, Vogelmeier CF, Bhatt SP, Anzueto A, Bafadhel M, Christenson SA, Puggioni F, Zheng J, Papi A, Singh D, Bauer D, Soliman M, Heble J, Hanania NA. Am J Respir Crit Care Med, 2026 Oct 30;Journal ArticleDupilumab is associated with improved lung functions in patients with COPD and type 2 inflammation: a post hoc analysis of the BOREAS and NOTUS trials.
DOI:10.1093/ajrccm/aamag572 PMID: 42968390 -
Sciurba FC, Watz H, Bourdin A, Janssens W, Martinez FJ, Zheng J, van den Berge M, Bonini M, Han MK, Singh D, Criner GJ, Brightling CE, Papi A, Bhatt SP, Jenkins M, Mikosz M, Chołbiński P, Ziemiecka M, Löfdahl M, Arya D, Yadavalli M, Brodek BH, Fagerås M, Bardsley S, Martin N, Patel R, Psallidas I, OBERON and TITANIA Trial Investigators , OBERON Trial Investigators , TITANIA Trial Investigators . N Engl J Med, 2026 Oct 29; 395 (17): 1703 - 1716.Journal ArticleTozorakimab to Prevent COPD Exacerbations.
DOI:10.1056/NEJMoa2606998 PMID: 42708515 -
Papi A, Han MLK, Rogliani P, Wedzicha JA, Miravitlles M. Respiratory Medicine, 2026 Oct 1; 262:Journal ArticleCOPD case finding and identification of at-risk individuals: opportunities for early personalized intervention and disease interception
DOI:10.1016/j.rmed.2026.109080 PMID: 42562238 -
Goodenberger KE, Bose S, Murray SK, Bosma CB, Han MLK, Curtis JL, Labaki WW. Annals of the American Thoracic Society, 2026 Oct 1; 23 (10): 1488 - 1496.Journal ArticleFood insecurity is associated with COPD prevalence and mortality: evidence from U.S. county-level data
DOI:10.1093/annalsats/aaoag096 PMID: 42033021 -
Han MK, Aaron SD, Bui D, Celli BR, DeBoer E, Dharmage S, Halpin DMG, Martinez FJ, Ozoh OB, Singh D, Vogelmeier C, Wedzicha J, Agusti A. Am J Respir Crit Care Med, 2026 Sep 29;Journal ArticleA GOLD Science Committee Report on Universal Longitudinal Spirometry: A New Paradigm.
DOI:10.1093/ajrccm/aamag432 PMID: 42809221 -
Hermann EA, Hoffman EA, Angelini ED, Barjaktarevic I, Bon J, Comellas A, Cooper CB, Couper D, Curtis JL, Criner G, Wells JM, Paine R, Krishnan JA, Labaki W, Laine AF, Lynch DA, Han MK, Hansel NN, Martinez FJ, Ortega V, Smith B, Sun Y, Woodruff P, Barr RG. Am J Respir Crit Care Med, 2026 Sep 25;Journal ArticleOne-year progression of CT emphysema subtypes predict lung function decline: SPIROMICS.
DOI:10.1093/ajrccm/aamag497 PMID: 42788667 -
Labaki W, Lagisetty K, Reddy R, Meldrum C, Wayne M, Curtis J, Sauler M, Bose S, Murray S, Oyer J, Hatt C, Kazerooni E, Han M, Galban C, Ram S. 2026 Oct 31; oa1297Proceeding / Abstract / PosterChest CT-Based Machine Learning for Predicting Response to Lung Volume Reduction Surgery: A Pilot Study
DOI:10.1183/13993003.congress-2026.oa1297 -
Hatt C, Labaki W, Galban C, Kazerooni E, Meldrum C, Xu L, Murray S, Sjoding M, Cox A, Othman A, Han M. 2026 Oct 31; pa2498Proceeding / Abstract / PosterMachine Learning Outperforms Traditional Quantitative Methods for CT-based COPD Diagnosis: An Analysis of the National Lung Cancer Screening Trial
DOI:10.1183/13993003.congress-2026.pa2498
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