MeiLan K Han MD, MS

Meilan K. Han
Henry Sewall Professor of Medicine
Professor of Internal Medicine and Section Head, Division of Pulmonary and Critical Care Medicine, Medical School
Office:
University of Michigan
Pulmonary & Critical Care Medicine
1150 West Medical Center Drive, 6220C MSRB III
Ann Arbor, MI 48109
Available to mentor
MeiLan K Han MD, MS
Meilan K. Han
Professor
  • About
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  • Center Memberships
  • Research Overview
  • Recent Publications
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  • About

    MeiLan Han, MD MS, is a Professor of Medicine and Chief of the Division of Pulmonary and Critical Care at the University of Michigan Health. Dr. Han received her medical degree from the University of Washington in Seattle, WA. She completed her residency in Internal Medicine and fellowship in Pulmonary and Critical Care Medicine at the University of Michigan. Dr. Han has also completed a Master's Degree program in Biostatistics and Clinical Study Design at the University of Michigan School of Public Health.

    Dr. Han’s research has focused on defining phenotypes in COPD using imaging. She is a lead investigator for several NIH sponsored COPD studies. She also serves as a spokesperson for the American Lung Association and on the board for the COPD Foundation. She is currently a Deputy Editor for the American Journal of Respiratory and Critical Care Medicine and serves as a member of the Global Obstructive Lung Disease scientific committee which is charged with developing internationally an internationally recognized consensus statement on COPD diagnosis and management. She is also the author of a book on lung health for the lay public, Breathing Lessons.

    Links

    • http://drmeilanhan.com/
    • Breathing Lessons
    • twitter
    • linkedin
    • instagram
    • facebook

    Center Memberships

    • Center Member
      Rogel Cancer Center
    • Center Member
      AI and Digital Health Innovation
    • Center Member
      Weil Institute for Critical Care Research
    • Center Member
      Taubman Institute

    Research Overview

    Dr. Han’s research focuses on understanding patient heterogeneity to define disease subtypes in chronic obstructive pulmonary disease (COPD). In particular, Dr. Han has expertise in thoracic CT imaging with a particular focus on better understanding early disease and diversity in the pathways towards disease progression. Working with colleagues at the University of Michigan, Dr. Han has helped to validate the application of a dynamic image registration technique (Parametric Response Mapping) to thoracic CT scans in COPD. She is the University of Michigan Principal Investigator for both the SPIROMICS and COPDGene studies which are NIH funded cohort studies in COPD.

    Recent Publications

    See All Publications
    • Journal Article
      Dupilumab is associated with improved lung functions in patients with COPD and type 2 inflammation: a post hoc analysis of the BOREAS and NOTUS trials.
      Han MK, Rabe KF, Sciurba FC, Vogelmeier CF, Bhatt SP, Anzueto A, Bafadhel M, Christenson SA, Puggioni F, Zheng J, Papi A, Singh D, Bauer D, Soliman M, Heble J, Hanania NA. Am J Respir Crit Care Med, 2026 Oct 30; DOI:10.1093/ajrccm/aamag572
      PMID: 42968390
    • Journal Article
      Tozorakimab to Prevent COPD Exacerbations.
      Sciurba FC, Watz H, Bourdin A, Janssens W, Martinez FJ, Zheng J, van den Berge M, Bonini M, Han MK, Singh D, Criner GJ, Brightling CE, Papi A, Bhatt SP, Jenkins M, Mikosz M, Chołbiński P, Ziemiecka M, Löfdahl M, Arya D, Yadavalli M, Brodek BH, Fagerås M, Bardsley S, Martin N, Patel R, Psallidas I, OBERON and TITANIA Trial Investigators , OBERON Trial Investigators , TITANIA Trial Investigators . N Engl J Med, 2026 Oct 29; 395 (17): 1703 - 1716. DOI:10.1056/NEJMoa2606998
      PMID: 42708515
    • Journal Article
      COPD case finding and identification of at-risk individuals: opportunities for early personalized intervention and disease interception
      Papi A, Han MLK, Rogliani P, Wedzicha JA, Miravitlles M. Respiratory Medicine, 2026 Oct 1; 262: DOI:10.1016/j.rmed.2026.109080
      PMID: 42562238
    • Journal Article
      Food insecurity is associated with COPD prevalence and mortality: evidence from U.S. county-level data
      Goodenberger KE, Bose S, Murray SK, Bosma CB, Han MLK, Curtis JL, Labaki WW. Annals of the American Thoracic Society, 2026 Oct 1; 23 (10): 1488 - 1496. DOI:10.1093/annalsats/aaoag096
      PMID: 42033021
    • Journal Article
      A GOLD Science Committee Report on Universal Longitudinal Spirometry: A New Paradigm.
      Han MK, Aaron SD, Bui D, Celli BR, DeBoer E, Dharmage S, Halpin DMG, Martinez FJ, Ozoh OB, Singh D, Vogelmeier C, Wedzicha J, Agusti A. Am J Respir Crit Care Med, 2026 Sep 29; DOI:10.1093/ajrccm/aamag432
      PMID: 42809221
    • Journal Article
      One-year progression of CT emphysema subtypes predict lung function decline: SPIROMICS.
      Hermann EA, Hoffman EA, Angelini ED, Barjaktarevic I, Bon J, Comellas A, Cooper CB, Couper D, Curtis JL, Criner G, Wells JM, Paine R, Krishnan JA, Labaki W, Laine AF, Lynch DA, Han MK, Hansel NN, Martinez FJ, Ortega V, Smith B, Sun Y, Woodruff P, Barr RG. Am J Respir Crit Care Med, 2026 Sep 25; DOI:10.1093/ajrccm/aamag497
      PMID: 42788667
    • Proceeding / Abstract / Poster
      Chest CT-Based Machine Learning for Predicting Response to Lung Volume Reduction Surgery: A Pilot Study
      Labaki W, Lagisetty K, Reddy R, Meldrum C, Wayne M, Curtis J, Sauler M, Bose S, Murray S, Oyer J, Hatt C, Kazerooni E, Han M, Galban C, Ram S. 2026 Oct 31; oa1297 DOI:10.1183/13993003.congress-2026.oa1297
    • Proceeding / Abstract / Poster
      Machine Learning Outperforms Traditional Quantitative Methods for CT-based COPD Diagnosis: An Analysis of the National Lung Cancer Screening Trial
      Hatt C, Labaki W, Galban C, Kazerooni E, Meldrum C, Xu L, Murray S, Sjoding M, Cox A, Othman A, Han M. 2026 Oct 31; pa2498 DOI:10.1183/13993003.congress-2026.pa2498

    Featured News & Stories

    Breathe 3 Pulm Group
    Department News

    BREATHE-3 study offers lifeline to Michigan patients with severe emphysema

    University of Michigan researchers have treated the state's first COPD patient with the investigational Apreo BREATHE Airway Scaffold as part of the BREATHE-3 study. The technology reshapes diseased airways to reduce trapped air, offering a new option for severe emphysema patients who do not qualify for traditional treatments.
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    Health Lab

    Lung health expert weighs in on Zyn and other nicotine pouches

    Michigan Medicine’s MeiLan Han, M.D., provides her professional and medical thoughts on the use of nicotine pouches.
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    Department News

    CME Event - Updates in the Diagnosis and Treatment of Interstitial Lung Disease

    Join University of Michigan experts on Tuesday, January 27, 2026 from 2-3 pm for a free virtual panel discussion on the current updates in the diagnosis and treatment of interstitial lung disease.
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    Health Lab

    Wildfires: How to protect your lung health in poor air quality

    With raging wildfires affecting air quality, experts say protecting your lung health is key.
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    Department News

    Breaking New Ground in COPD: Latest Treatments and Advances in Management

    Join us for a free virtual panel discussion, Breaking New Ground in COPD: Latest Treatments and Advances in Management, on Tuesday, January 14, 2025.