MeiLan K Han MD, MS

Meilan K. Han
Henry Sewall Professor of Medicine
Professor of Internal Medicine and Section Head
Division of Pulmonary and Critical Care Medicine
Medical School
University of Michigan
Pulmonary & Critical Care Medicine
1150 West Medical Center Drive, 6220C MSRB III
Ann Arbor, MI 48109
Available to mentor
MeiLan K Han MD, MS
Meilan K. Han
Professor
  • About
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  • Center Memberships
  • Research Overview
  • Recent Publications
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  • About

    MeiLan Han, MD MS, is a Professor of Medicine and Chief of the Division of Pulmonary and Critical Care at the University of Michigan Health. Dr. Han received her medical degree from the University of Washington in Seattle, WA. She completed her residency in Internal Medicine and fellowship in Pulmonary and Critical Care Medicine at the University of Michigan. Dr. Han has also completed a Master's Degree program in Biostatistics and Clinical Study Design at the University of Michigan School of Public Health.

    Dr. Han’s research has focused on defining phenotypes in COPD using imaging. She is a lead investigator for several NIH sponsored COPD studies. She also serves as a spokesperson for the American Lung Association and on the board for the COPD Foundation. She is currently a Deputy Editor for the American Journal of Respiratory and Critical Care Medicine and serves as a member of the Global Obstructive Lung Disease scientific committee which is charged with developing internationally an internationally recognized consensus statement on COPD diagnosis and management. She is also the author of a book on lung health for the lay public, Breathing Lessons.

    Links

    • http://drmeilanhan.com/
    • Breathing Lessons
    • twitter
    • linkedin
    • instagram
    • facebook

    Center Memberships

    • Center Member
      AI and Digital Health Innovation
    • Center Member
      Weil Institute for Critical Care Research
    • Center Member
      Taubman Institute

    Research Overview

    Dr. Han’s research focuses on understanding patient heterogeneity to define disease subtypes in chronic obstructive pulmonary disease (COPD). In particular, Dr. Han has expertise in thoracic CT imaging with a particular focus on better understanding early disease and diversity in the pathways towards disease progression. Working with colleagues at the University of Michigan, Dr. Han has helped to validate the application of a dynamic image registration technique (Parametric Response Mapping) to thoracic CT scans in COPD. She is the University of Michigan Principal Investigator for both the SPIROMICS and COPDGene studies which are NIH funded cohort studies in COPD.

    Recent Publications

    See All Publications
    • Journal Article
      Defining disease stability in COPD: Evidence from Phase 3 clinical trials.
      Singh D, Stacey R, Halpin DMG, Bhatt SP, Crawford J, Drury T, Di Boscio V, Kolterer S, Han MK. Am J Respir Crit Care Med, 2026 Jun 11; DOI:10.1093/ajrccm/aamag292
      PMID: 42281286
    • Journal Article
      A15-05 Screening for Interstitial Lung Disease Using Quantitative CT Thresholds
      Wang JM, Pugashetti JV, Murray S, Mohan N, Kang E, Kazerooni E, Flaherty KR, Belloli E, Sheth JS, O’Dwyer DN, Han MK, Hatt CR, Oldham J. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.2203 DOI:10.1093/ajrccm/aamag162.2203
    • Journal Article
      A16-01 The Respiratory Effects Of Prematurity Extend Over The Lifespan: Analyses From The SPIROMICS And SOURCE Studies
      Aoyama BC, Collaco JM, Mcgrath-Morrow SA, Curtis JL, Barjaktarevic I, Bosma C, Cooper CB, Hansel NN, Han MK, Hoffman EA, Paine R, Putcha N, Smith BM, Martinez FJ, Woodruff P, Neptune ER, Fawzy A, Raju S. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.1585 DOI:10.1093/ajrccm/aamag162.1585
    • Journal Article
      A16-04 Significance of Mucus Plugs in Early COPD: An Analysis of the SOURCE Cohort
      Ram S, Oyer JM, Ng AS, Labaki WW, Bosma C, Curtis JL, Kazerooni EA, Hatt CR, Paine R, Soni AV, Ritchie AI, Wedzicha JA, Bateman LA, Hoffman EA, Martinez FJ, Galban CJ, Han MK, Investigators SAS. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.1588 DOI:10.1093/ajrccm/aamag162.1588
    • Journal Article
      A20-01 One-year Progression in Quantitative CT Parameters Predicts Subsequent Lung Function Decline Over 5 Years: The Subpopulations and Intermediate Outcome Measures in COPD Study (Spiromics)
      Hermann EA, Hoffman EA, Angelini E, Barjaktarevic I, Bon J, Comellas AP, Cooper CB, Couper D, Curtis JL, Criner GJ, Wells M, Paine R, Krishnan JA, Labaki WW, Laine A, Lynch DA, Han MK, Hansel NN, Martinez FJ, Smith BM, Sun Y, Woodruff P, Barr RG. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.1595 DOI:10.1093/ajrccm/aamag162.1595
    • Journal Article
      A34-12 Tezepelumab Was Associated With Lower Rates of COPD-related Healthcare Resource Utilization in Patients With Moderate to Very Severe COPD With Elevated Blood Eosinophil Counts: Results From the Phase 2a COURSE Study
      Criner GJ, Maselli DJ, Han MK, Drummond MB, Marchese C, Ambrose CS, Molfino NA, Ponnarambil S. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.1630 DOI:10.1093/ajrccm/aamag162.1630
    • Journal Article
      A34-13 Effect of Tezepelumab on Systemic Corticosteroid Use for Exacerbations in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease by Blood Eosinophil Count: The COURSE Study
      Criner GJ, Chupp GL, Han MK, Singh D, Marchese C, Molfino NA, Matsunaga Y, Ponnarambil S, Ambrose CS. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.1631 DOI:10.1093/ajrccm/aamag162.1631
    • Journal Article
      A34-21 Disease Stability Is Achievable in a Wide Spectrum of Patients With Chronic Obstructive Pulmonary Disease Receiving Mepolizumab: Pooled Results From Phase III Randomized Controlled Trials
      Singh D, Vogelmeier CF, Martinez FJ, Roche N, Watz H, Biswas A, Stacey R, Kolterer S, Han MK. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.1639 DOI:10.1093/ajrccm/aamag162.1639

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