Amy M Kilbourne
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About
Dr. Amy M. Kilbourne, PhD, MPH is Professor, Department of Learning Health Sciences, University of Michigan (UM) Medical School and Acting Deputy Chief Research and Development Officer for Investigators, Scientific Review and Management for the U.S. Department of Veterans Affairs (VA) Office of Research and Development. She is a national expert in implementation science, notably the development and testing of strategies that support health care providers in delivering effective treatments and innovations more rapidly to their patients. Dr. Kilbourne has led several national implementation initiatives across the U.S. to improve patient outcomes including quality, cost, and experience, and developed national research agendas focused on health disparities, mental health, chronic conditions, and Learning Health Systems. She also leads MICHR's Dissemination and Implementation (D&I) Catalyst, a U-M-wide initiative to promote implementation science across the translation spectrum, to ultimately enhance the uptake of evidence-based practices in real-world settings. In her VA role Dr. Kilbourne is also supporting VA’s Quality Enhancement Research Initiative (QUERI) which funds investigators to accelerate the implementation of research evidence into practice, and the VA's fulfillment of the Foundations for Evidence-based Policymaking Act, which requires government agencies to use evidence and evaluation to justify program budgets.
Center Memberships
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Center MemberCaswell Diabetes Institute
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Center MemberUniversity of Michigan Injury Prevention Center
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Center MemberInstitute for Healthcare Policy and Innovation
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Center MemberEisenberg Family Depression Center
Research Overview
Translational Science, Learning Health Systems research, and Implementation Science
Adaptive designs and sequential multiple assignment randomized trials (SMARTs)
Integrated collaborative care model interventions in learning health systems and community-based practices
Evidence-based policy with a focus on quality improvement and evaluation methods
Recent Publications
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Harvey AG, Agnew ER, Esteva Hache R, Callaway CA, Ovalle Patino E, Milner A, Spencer JM, Diaz M, Dong L, Kilbourne AM, Buysse DJ, Stice E, Sarfan LD. Implementation Science, 2026 Dec 1; 21 (1):Journal ArticleA randomized trial of adapted versus standard versions the transdiagnostic intervention for sleep and circadian dysfunction (TSC) implemented via facilitation and delivered by community mental health providers using train-the-trainer
DOI:10.1186/s13012-025-01467-y PMID: 41318500 -
Flood D, Wellmann Castellanos IAM, Ayala LF, Tschida S, Chary AN, Donis R, Alvarez Nufio AIA, Kilbourne AM, Watkins D, Huffman MD, Rice JD, Rohloff P, Ramírez-Zea M. Implementation Science Communications, 2026 Dec 1; 7 (1):Journal ArticleEvaluating implementation of the HEARTS model for management of hypertension and diabetes in Guatemala: protocol for a prospective observational hybrid type 3 study
DOI:10.1186/s43058-026-00993-0 -
Sridhar R, Hallway AK, Kilbourne AM, Telem DA, Ehlers AP. Annals of Surgery, 2026 Oct 1; 284 (4): 862 - 863.Journal ArticleDurability of Practice Change in Hernia Surgery Following De-implementation of Intensive Implementation Strategies
DOI:10.1097/SLA.0000000000007086 PMID: 42108500 -
Bravata DM, Schubert CC, Kilbourne AM, Hartronft SR, Schwartzkopf AL, Myers JL, Flanagan ME, Donnelly CE, Taylor SE, Reeves MJ, Perkins AJ, Myers LE, Roy I, Burke RE, Beard RA, Montagnini M, Jindal SK, Arling G, Madrigal C, Rattray NA. Journal of General Internal Medicine, 2026 Oct 1; 41 (13): 3666 - 3675.Journal ArticleLeading Learning Health Systems: Strategies Used to Establish and Conduct a Learning Health System
DOI:10.1007/s11606-025-09849-0 PMID: 40999263 -
Horton DM, Shi G, Davis MA, Grau PP, Kilbourne AM. Journal of Traumatic Stress, 2026 Oct 1; 39 (5): 775 - 784.Journal ArticlePacing in posttraumatic stress disorder therapy: A meta-regression of treatment frequency and completion rates
DOI:10.1002/jts.70111 PMID: 42504047 -
Ehlers AP, Kilbourne A, Hodson N, Telem DA. JAMA Surgery, 2026 Sep 9; 161 (9): 857 - 858.Journal ArticleBoosting Implementation Efforts With Behavioral Economics
DOI:10.1001/jamasurg.2026.2540 PMID: 42418162 -
Wang L, Desai H, Teerlink C, Clark O, Pridgen KM, Lee J, Chang KM, Kember RL, Vujkovic M, Lynch JA, Maxwell KN, Muralidhar S, Moser J, Deen JE, Tsao PS, Gaziano JM, Hauser E, Kilbourne A, Matheny M, Oslin D, Voora D, Brewer JV, Brophy MT, Cho K, Churby L, DuVall SL, Pyarajan S, Ringer R, Selva LE, Shayan S, Stephens B, Whitbourne SB, Assimes TL, Hung A, Kranzler H. JCO Precision Oncology, 2026 Sep 1; 10 (9):Journal ArticleCross-Ancestry and Phenome-Wide Associations of Cancer-Specific Polygenic Risk Scores
DOI:10.1200/PO-25-00957 PMID: 42753222 -
Williams AR, Houghton SC, Li Y, Gagnon D, Ho Y-L, Cho K, Gaziano JM, Whitbourne SB, Nguyen X-MT, VA Million Veteran Program . Mil Med, 2026 Sep 1; 191 (9-10): e2093 - e2099.Journal ArticleCross-sectional Comparison of Social Drivers of Health in The Million Veteran Program and Behavioral Risk Factor Surveillance System (2011-2023).
DOI:10.1093/milmed/usag030 PMID: 41691648