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Researchers have discovered a new molecular process that occurs when donor hearts are preserved in cold storage which contributes to failure after transplant, a study in both humans and animals shows. Fortunately, therapy that is typically prescribed for high blood pressure can target this process to reduce cold preservation associated with cardiac injury. This discovery has potential to improve the consistent function of donor hearts and extend the distance they can be safely transported in cold storage.

Telemedicine use in 2023 reduced monthly carbon dioxide emissions by the equivalent of up to 130,000 gas operated vehicles, suggesting it could have a positive effect on climate change, UCLA and Michigan led research finds.

Children living with parents who have addiction issues, also called substance used disorder, have higher risks later in life. A new study shows 1 in 4 currently live in such households.

University of Michigan researchers have identified that the balance between two proteins—STAT3 and STAT5—is important for making tumors vulnerable to immune checkpoint therapy, and targeting STAT3 degradation is a potential novel cancer immunotherapy strategy.

Researchers used mouse models and studies of colorectal cancer tissues to show that loss of SOX9 gene promotes tumor progression and the pathway it regulates can be a potential target for future treatments.

The immune system is showing evidence of playing a roll in the emergence of atherosclerotic cardiovascular disease. A rush of neutrophils, or immune cells to the site could be an explanation for how this condition forms as well as how to prevent this heart disease in the future.

Research on the inflammatory mediator called sCD13 has identified this molecule and its receptors as new targets for treatment of autoimmune rheumatic diseases. The data suggests that sCD13 may also be of great importance in severe complications of COVID-19.

Research improves upon a popular experimental model revealing more of the inner workings of a critical period during the formation of an embryo.

Buprenorphine prescription interruptions were most common in states that had the biggest coverage drops during Medicaid unwinding; study has importance for future Medicaid policy.

Poll of people over 50 shows most haven’t signed legal documents, discussed their wishes with family or friends, or done other things to plan for long term care needs.

Older drivers with vision impairment are much more likely to stop driving or avoid challenging road conditions a national University of Michigan study found.

Researchers at University of Michigan showed that the proportion of patients undergoing prostatectomy for the lowest risk type of cancer dropped over fivefold between 2010 to 2024.

Robotic-assisted cholecystectomies produce a higher risk of bile duct injuries than laparoscopic cholecystectomies for patients at all types of risks.

The discontinuation of a popular asthma medication was linked to a higher rate of children stopping inhaled steroid therapy altogether, a study suggests.

Researchers investigated the combined effects of bazedoxifene and conjugated estrogens in rat models as an alternative to tamoxifen.