Biological Chemistry Research
A biochemistry researcher examines a specimen in the lab

Asking and Answering Fundamental Questions

We explore biological phenomena at the molecular and mechanistic levels to make discoveries about life and health.

Understanding the Foundations of Life

Scientists in the Department of Biological Chemistry integrate many technologies and approaches to study the molecular processes that are the foundation for life and health. Research projects can be grouped into the four broad areas of Biochemical Signaling, Macromolecular Structure & Mechanism, Protein Processing & Folding and Regulation of Gene Expression.

Close ties and cross-appointments with the Life Sciences Institute, the Center for RNA Biomedicine, the Michigan Neuroscience Institute, the Chemical Biology Program, and the LSA departments of Biology, Biophysics, and Chemistry place Biological Chemistry at the center of the University of Michigan's strong biochemical community. 

Our interdisciplinary research into the molecular mechanisms of life offers a wide variety of investigative opportunities to students, fellows, and scientific collaborators.

Research Areas
man using pipette in laboratory
Biochemical Signaling

Probe how cells respond to changes in their environment.

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Macromolecular Structure & Mechanism

Focus in on how biological macromolecules function at the molecular and atomic level.

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woman in a laboratory is leaned over while operating a microscope
Protein Processing & Folding

Understanding the folding, translocation, and processing of proteins is integral to modern molecular and cell biology.

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Regulation of Gene Expression

Use and develop groundbreaking research techniques to uncover the mechanisms that govern gene expression.

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Biological Chemistry News & Stories See all news 2025 Endowment for Basic Sciences Awards
Medical School News
Eighteen from UMMS honored with 2025 Endowment for Basic Sciences Awards
Nine Medical School faculty members and nine research staff members have been recognized for their contributions to teaching and research with Endowment for Basic Sciences (EBS) Awards for 2025. Each of the nine UMMS basic science departments select a winner for each award. This year’s recipients received their awards June 12 during a ceremony in the Medical School.
headshot of Zoe Yeoh
Department News
Congratulations to Zoe Yeoh, PhD
Biological Chemistry PhD student Zoe Yeoh of the Janet Smith and Melanie Ohi labs defends her doctoral dissertation.
Outdoor group photo of student award winner with faculty
Department News
Esme Lowry receives Master's Program Award
Esme Lowry has received a U-M Medical School Master's Program Award.
headshot of Aminoff endowment award winner
Department News
PhD student Jennifer Russ receives the 2025 David Aminoff Endowment Award
PhD student Jennifer Russ in the Department of Biological Chemistry at U-M Medical School has received the 2025 David Aminoff Endowment Award.
Headshots of EBS awardwinners with trophy
Department News
Chase Weidmann and Daniel Esckilsen receive Endowment for Basic Sciences Awards
Assistant Professor Chase Weidmann and Research Lab Specialist Daniel Esckilsen are the 2025 recipients of Endowment for Basic Sciences (EBS) Awards for the Department of Biological Chemistry at U-M Medical School.
headshot of Victor Rivera-Santana
Department News
Congratulations to Victor Rivera-Santana, PhD
Biological Chemistry PhD student Victor Rivera-Santana of the Marsh lab defends his doctoral dissertation.