Biological Chemistry Research
A biochemistry researcher examines a specimen in the lab

Asking and Answering Fundamental Questions

We explore biological phenomena at the molecular and mechanistic levels to make discoveries about life and health.

Understanding the Foundations of Life

Scientists in the Department of Biological Chemistry integrate many technologies and approaches to study the molecular processes that are the foundation for life and health. Research projects can be grouped into the four broad areas of Biochemical Signaling, Macromolecular Structure & Mechanism, Protein Processing & Folding and Regulation of Gene Expression.

Close ties and cross-appointments with the Life Sciences Institute, the Michigan Neuroscience Institute, the Chemical Biology Program, the LSA departments of Biology, Biophysics, and Chemistry, as well as fellow Medical School departments, position Biological Chemistry at the center of a strong and diverse biochemical community at the University of Michigan.

Our interdisciplinary research into the molecular mechanisms of life offers a wide variety of investigative opportunities to students, fellows, and scientific collaborators.

Research Areas
man using pipette in laboratory
Biochemical Signaling

Probe how cells respond to changes in their environment.

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man in labradory pouring liquid into a tank
Macromolecular Structure & Mechanism

Focus in on how biological macromolecules function at the molecular and atomic level.

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woman in a laboratory is leaned over while operating a microscope
Protein Processing & Folding

Understanding the folding, translocation, and processing of proteins is integral to modern molecular and cell biology.

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students in a lab working and wearing latex gloves
Regulation of Gene Expression

Use and develop groundbreaking research techniques to uncover the mechanisms that govern gene expression.

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Meet our laboratory researchers
suzanne admiraal Suzanne Admiraal, PhD
Research Lab Specialist
Patrick O'Brien Lab
sojin an Sojin An, PhD
Research Lab Specialist
Uhn-Soo Cho Lab
Catherine baker Catherine Baker
Research Lab Specialist
James Morrissey Lab
Michael Baldwin Michael Baldwin
Research Lab Specialist
Patrick O'Brien Lab
Brittney bowman Brittany Bowman, PhD
Research Lab Specialist
Chase Weidmann Lab
jue chen Jue (Amy) Chen
Research Lab Technician
Yan Zhang Lab
Daniel esckilsen Daniel Esckilsen
Research Lab Specialist
Stephen Ragsdale Lab
user Jean-Marc Fontaine, PhD
Research Lab Specialist
Raymond Trievel Lab
Rachel hemp Rachel Hemp
Research Lab Specialist
James Morrissey Lab
rebecca hurto Rebecca Lee Hurto, PhD
Research Lab Specialist
Lydia Freddolino Lab
zhu li Zhu Li, PhD
Research Lab Specialist
Ruma Banerjee Lab
manolo plasencia Manolo Plasencia, PhD
Research Lab Specialist
Lydia Freddolino Lab
headshot of  krishna-rengasamy Krishna Rengasamy
Research Lab Specialist
Uhn-Soo Cho Lab
Andrew shurer Andrew Shurer
Research Lab Specialist
Rachel Niederer Lab
user Sophia Taylor
Research Lab Technician
Ryan Baldridge Lab
user Kazuhiro Yamada, PhD
Research Lab Specialist
Ruma Banerjee Lab
xufei zhou Xufei Zhou, PhD
Research Lab Specialist
Yan Zhang Lab
Biological Chemistry News & Stories See all news Headshots of two new Genetics Training Program members
Department News
Graduate students Ross Kaufhold and Ben Pockrass chosen for training program positions
Two Biological Chemistry graduate students receive positions in the Genetics Training Program for the 2024–2025 academic year.
headshot of Jenna Veenstra
Department News
Congratulations to Jenna Veenstra, PhD
Biological Chemistry PhD student Jenna Veenstra of the O'Brien lab at U-M Medical School defends her doctoral dissertation.
headshot of Cassandra Dutcher
Department News
Congratulations to Cassandra Dutcher, PhD
Biological Chemistry PhD student Cassandra Dutcher of the Giessen lab at U-M Medical School defends her doctoral dissertation.
Headshot of Renke Tan
Department News
Congratulations to Renke Tan, PhD
Biological Chemistry PhD student Renke Tan of the Zhang lab at U-M Medical School defends her doctoral thesis.
Headshot of Michael Uhler
Department News
Michael Uhler, PhD, retires from active faculty status
Congratulations and best wishes to Michael Uhler, PhD, Professor Emeritus of Biological Chemistry and Research Professor Emeritus, Michigan Neuroscience Institute.
Headshots of three PhD students
Department News
PhD students Megan Medina, Tyler Brant, and Ashley Scheutzow chosen for training program positions
Three Biological Chemistry PhD students receive positions in training programs for the 2024–2025 academic year.