A musician receives live donor cartilage that changes her life.

In the second season of The Fundamentals podcast, co-hosts Kelly Malcom and Jordan Goebig talk to several leading experts from the Medical School about their fields and the fundamental questions they are trying to answer — and discover why U-M is such an amazing place for research. Six new episodes of the popular podcast were released on May 6

Today on The Fundamentals is Dr. Maria Castro, the R.C. Schneider collegiate professor of neurosurgery, and a professor of cell and developmental biology at the University of Michigan Medical School. Her research program aims to develop immunotherapies for primary and metastatic brain cancer, studying basic immune biology mechanisms leading to clinical implementation. She has been inducted into the American Association for the Advancement of Sciences, the Latin American Academy of Sciences, and the American Institute for Medical and Biological Engineering College of Fellows. She has won numerous awards for her contributions to basic science and cancer research and is a diversity ambassador for the Cancer Biology Graduate Training Program. You can learn more about Dr. Castro here, and you can follow her @castro2355_mg, the Rogel Cancer Center @UMRogelCancer, the department of neurosurgery @umichneuro, Michigan Neurscience Institute @UM_MNI and the department of cell and developmental biology @UMCDB on X

Researchers improved memory and reduced neuroinflammation in a mouse model of Alzheimer’s Disease, suggesting another avenue for potential treatment.

Among people with multiple sclerosis in the United States, more than half experienced at least one fall in a six-month period and approximately one-third of those falls resulted in an injury.

At the University of Michigan Health C.S. Mott Children's Hospital, one physician found a way to help pediatric patients demonstrate different joint movements using a Barbie doll.

A growing number of people living with Alzheimer’s disease and related dementias – especially those from diverse backgrounds – receive care from a network of individuals that increasingly includes nontraditional informal caregivers.

The death rate for patients with functional, nonepileptic seizures is higher than expected, with a rate comparable to epilepsy and severe mental illness, a Michigan Medicine-led study finds.

Investigators found that people with obesity who underwent bariatric surgery had stable cognition two years later. Researchers say it suggests that bariatric surgery may mitigate the natural history of cognitive decline expected in people with obesity.

Post-traumatic stress worse among Mexican American caregivers compared to white caregivers.

A Michigan Medicine expert breaks down what ulnar neuropathy is and how electrodiagnostic studies can assess severity and guide management, which can sometimes include conservative treatment and education on how to protect the nerve.

Piotrowski consulted with a spectrum of doctors, physical therapists and chiropractors, each with a different recommendation for how to treat a herniated disc in the lower portion of his spine until he found one at Michigan Medicine recommending lumbar microdiscectomy, a procedure that involves small incisions to remove portions of the herniated disc and ease pressure on the spinal cord nerves.

A car accident at age 20 left Sahar Mashhour in the intensive care unit for three months. Almost six years later, Mashhour is still pursuing her passions proving that her disability doesn’t limit her ability, but instead helps her see life through a different lens.

Last year, a young girl experienced up to 40 seizures a week. Today, after nearly a year of working with the ketogenic diet team at University of Michigan Health C.S. Mott Children’s Hospital – overseen by a pediatric neurologist and dietitian – she’s celebrating six months of seizure freedom.

Research published in the Arthritis Care and Research Journal from Michigan Medicine found that scleroderma patients made significant strides when working with trained peer health coaches in adhering to wellness routines, leading to resilience and improvements in fatigue, pain and depressive symptoms.