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The Fundamentals
If they don't give up, how can I give up?
Today on The Fundamentals is Dr. Maria Castro, the R.C. Schneider collegiate professor of neurosurgery, and a professor of cell and developmental biology at the University of Michigan Medical School. Her research program aims to develop immunotherapies for primary and metastatic brain cancer, studying basic immune biology mechanisms leading to clinical implementation. She has been inducted into the American Association for the Advancement of Sciences, the Latin American Academy of Sciences, and the American Institute for Medical and Biological Engineering College of Fellows. She has won numerous awards for her contributions to basic science and cancer research and is a diversity ambassador for the Cancer Biology Graduate Training Program. You can learn more about Dr. Castro here, and you can follow her @castro2355_mg, the Rogel Cancer Center @UMRogelCancer, the department of neurosurgery @umichneuro, Michigan Neurscience Institute @UM_MNI and the department of cell and developmental biology @UMCDB on X
Xray of a stem cell in a mouse brain.
Health Lab
Stem cells improve memory, reduce inflammation in Alzheimer’s mouse brains
Researchers improved memory and reduced neuroinflammation in a mouse model of Alzheimer’s Disease, suggesting another avenue for potential treatment.
brain image
Health Lab
Death rate higher than expected for patients with functional, nonepileptic seizures
The death rate for patients with functional, nonepileptic seizures is higher than expected, with a rate comparable to epilepsy and severe mental illness, a Michigan Medicine-led study finds.
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Health Lab
Bariatric surgery may slow cognitive decline for people with obesity
Investigators found that people with obesity who underwent bariatric surgery had stable cognition two years later. Researchers say it suggests that bariatric surgery may mitigate the natural history of cognitive decline expected in people with obesity.
Brain image highlighting areas
Health Lab
Nearly 30% of caregivers for severe stroke survivors experience psychological distress
Post-traumatic stress worse among Mexican American caregivers compared to white caregivers.
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Health Lab
Young man’s debilitating back pain a thing of the past
Piotrowski consulted with a spectrum of doctors, physical therapists and chiropractors, each with a different recommendation for how to treat a herniated disc in the lower portion of his spine until he found one at Michigan Medicine recommending lumbar microdiscectomy, a procedure that involves small incisions to remove portions of the herniated disc and ease pressure on the spinal cord nerves.
woman in hospital on left in ICU and the other right side woman standing in jean jacket and black clothes smiling
Health Lab
Brain tumor and car crash survivor aspires to be example for others living with disabilities
A car accident at age 20 left Sahar Mashhour in the intensive care unit for three months. Almost six years later, Mashhour is still pursuing her passions proving that her disability doesn’t limit her ability, but instead helps her see life through a different lens.
family smiling togehter
Health Lab
Ketogenic diet helps 4-year-old live seizure free
Last year, a young girl experienced up to 40 seizures a week. Today, after nearly a year of working with the ketogenic diet team at University of Michigan Health C.S. Mott Children’s Hospital – overseen by a pediatric neurologist and dietitian – she’s celebrating six months of seizure freedom.
vial of blood in container lab blue yellow grainy graphic
Health Lab
Drawing a tube of blood could assess ALS risk from environmental toxin exposure
Investigators have developed an environmental risk score that assesses a person’s risk for developing ALS, as well as for survival after diagnosis, using a blood sample.
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Health Lab
Scientists develop new model for understanding sudden death in epilepsy
Researchers at the University of Michigan have developed a model for studying one type of familial epilepsy, opening the door to understanding—and eventually targeting—the mechanisms that lead to the disorder and its associated fatalities.
cars jammed on highway
Health Lab
Nearly one-fifth of older adults travel 50-plus miles to see a neurologist
A Michigan Medicine study finds older Americans with complex neurologic conditions travel may travel great distances for care, many of whom live in rural areas or regions with a limited number of specialists.
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Health Lab
Gene therapy for brain tumor shows promising early results in humans
Research from the University of Michigan Department of Neurosurgery and Rogel Cancer Center shows promising early results that a therapy combining cell-killing and immune-stimulating drugs are safe and effective in extending survival for patients with gliomas, a highly aggressive form of brain cancer.
Text: 20+ top-ranked residency programs at the U-M Medical School. Image: Michigan Medicine logo with maize-colored M.
News Release
13 U-M graduate medical education programs ranked in the top 10 by Doximity
There are 13 U-M graduate medical education programs ranked in the top 10 by Doximity.
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Health Lab
Do you know what Moyamoya disease is?
Moyamoya disease is a rare condition that can cause blockage of the blood vessels in the brain and increase the risk of stroke. Learn more about this chronic disease from U-M Health’s neurologist and neurosurgeon as they explain more about how it is diagnosed and treated.
brain image
Health Lab
Majority of older adults with cognitive impairment still drive
The majority of older adults with cognitive impairment are still driving, despite concerns raised by caregivers and others, a Michigan Medicine study in a South Texas community finds.