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The Fundamentals
Treating Diabetes & Weight: The Ozempic & Wegovy Effect
Today on The Fundamentals, our guest Dr. Martin Myers, Director of the U-M Elizabeth Weiser Caswell Diabetes Institute, discusses diabetes research in the context of Ozempic, Wegovy, and other drugs that are changing how people think about weight loss. You can learn more about Dr. Myers here, and you can follow the department of molecular and integrative physiology @UMPhysiology on X.
Illustration of doctor pictured outside a pill bottle that houses a bent-over figure with pills lying on the ground
Health Lab
It’s easier now to treat opioid addiction with medication -- but use has changed little
Buprenorphine prescribing for opioid addiction used to require a special waiver from the federal government, but a new study shows what happened in the first year after that requirement was lifted.
Pill capsule pushing through a paper with amoxicillin printed on it.
Health Lab
Rise seen in use of antibiotics for conditions they can’t treat – including COVID-19
Overuse of antibiotics can lead bacteria to evolve antimicrobial resistance, but Americans are still receiving the drugs for many conditions that they can’t treat.
Close up image of red blood cells moving through veins
Health Lab
Discovery reveals how this common stinky gas is processed to promote blood vessel growth
A new collaborative study, examined the interaction between three naturally occurring gases — nitric oxide (NO), oxygen, and H2S — during generation of new blood vessels, called angiogenesis.
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Health Lab
Parents’ top resolutions: More patience, less time on phones
6 ways families can make resolutions stick
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Health Lab
Dental opioid prescriptions still declining, but not as quickly as pre-pandemic
Dental pain treatment with opioid painkillers like Oxycontin and Oxycodone declined before and during the pandemic but the rate of decline slowed after 2020.
flies moving sled in snow with person
Health Lab
Gene links exercise endurance, cold tolerance and cellular maintenance in flies
A study in PNAS identifies a protein that, when missing, makes exercising in the cold that much harder—that is, at least in fruit flies.
stethoscope
Health Lab
Genetic mutation linked to adrenal tumor and hypertension
Research from the Department of Molecular & Integrative Physiology at Michigan Medicine identifies a previously unknown genetic mutation that causes the disease called primary aldosteronism in certain populations.
dna strand in blue grainy off white background yellow spots
Health Lab
A new regulator of innate immunity identified
One of the most important protein complexes in mammals involved in ERAD is called SEL1L-HRD1. Recent research finds that this protein complex helps regulate another critical protein involved in innate immunity, called STING, at the endoplasmic reticulum.
black room with person visual far away walking towards glowing light
Health Lab
Evidence of conscious-like activity in the dying brain
A Michigan Medicine study provides early evidence of a surge of activity correlated with consciousness in the dying brain.
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Health Lab
Mouse study hints at specific brain receptor behind PCOS symptoms
Mouse study at Michigan Medicine hints at specific brain receptor behind PCOS symptoms.
couple with kid and medical bill with doctor
Health Lab
Even with private insurance, your child's hospitalization could cost $1,300
Study reveals privately insured families may spend $1,300 out-of-pocket for child hospitalization. High costs impact family wellbeing warns pediatric expert.
fly on green leaf
Health Lab
Fruit flies feast for pleasure as well as necessity
Study reveals the way flies are just like us when it comes to food.
Women in science collage
Health Lab
Scientists explain their passion, offer advice
Early career researchers describe their professional journeys to help inspire women and girls pursue careers in science
Microscope
Health Lab
Studying a protein modification process in worms provides potential insights for human health
Too much of this post-translational modification impacted multiple body systems