On today’s The Fundamentals is Dr. Brummett, Professor at the University of Michigan where he serves as the Senior Associate Chair for Research in the Department of Anesthesiology. He has more than 280 publications, including articles in top journals such as JAMA, JAMA Surgery, Anesthesiology, and Annals of Surgery. He is the Co-Director of the Opioid Prescribing Engagement Network or OPEN at the University of Michigan, which aims to apply a preventative approach to the opioid epidemic in the US through appropriate prescribing after surgery, dentistry and emergency medicine. Moreover, he is the Co-Director of the cross-campus Opioid Research Institute, which was launched in the spring of 2023. He leads multiple NIH grants studying these concepts and receives funding from the Michigan Department of Health and Human Services, SAMHSA, CDC, and multiple foundations. You can learn more about Dr. Brummett here, and you can follow Dr. Brummett @drchadb and the department of anesthesiology @UMichAnesthesia on X.

Today on The Fundamentals, our guest Dr. Martin Myers, Director of the U-M Elizabeth Weiser Caswell Diabetes Institute, discusses diabetes research in the context of Ozempic, Wegovy, and other drugs that are changing how people think about weight loss. You can learn more about Dr. Myers here, and you can follow the department of molecular and integrative physiology @UMPhysiology on X.

A new collaborative study, examined the interaction between three naturally occurring gases — nitric oxide (NO), oxygen, and H2S — during generation of new blood vessels, called angiogenesis.

Elective surgery study shows older adults have concerns about what it will cost them, how much work they’ll miss and whether they’ll catch COVID-19.

The process, also known as liver perfusion, works differently than traditional ischemic cold storage methods for donor livers by involving technology that recreates the optimal physiological conditions for the organ.

A study in PNAS identifies a protein that, when missing, makes exercising in the cold that much harder—that is, at least in fruit flies.

Research from the Department of Molecular & Integrative Physiology at Michigan Medicine identifies a previously unknown genetic mutation that causes the disease called primary aldosteronism in certain populations.

A recent study led by Sidra Bonner, M.D., M.P.H, M.S. a surgery resident at the University of Michigan Health, has now provided new information about the clinical impact of race-correction in pulmonary function tests for African American patients with lung cancer undergoing surgical evaluation.

Baby diagnosed with duodenal stenosis is doing great after complex surgery at C.S. Mott Children's Hospital in Ann Arbor

Gender-affirming care for transgender teens is restricted or may be soon in 20 states; this has increased travel time to available clinics

There are 13 U-M graduate medical education programs ranked in the top 10 by Doximity.

One of the most important protein complexes in mammals involved in ERAD is called SEL1L-HRD1. Recent research finds that this protein complex helps regulate another critical protein involved in innate immunity, called STING, at the endoplasmic reticulum.

Michigan Medicine researchers spearhead an innovative strategy allowing an artificial circuit to safely support premature sheep without anticoagulation, overcoming a major barrier in artificial placenta research.

A Michigan Medicine study provides early evidence of a surge of activity correlated with consciousness in the dying brain.

Mouse study at Michigan Medicine hints at specific brain receptor behind PCOS symptoms.