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The Fundamentals
Treating Diabetes & Weight: The Ozempic & Wegovy Effect
Today on The Fundamentals, our guest Dr. Martin Myers, Director of the U-M Elizabeth Weiser Caswell Diabetes Institute, discusses diabetes research in the context of Ozempic, Wegovy, and other drugs that are changing how people think about weight loss. You can learn more about Dr. Myers here, and you can follow the department of molecular and integrative physiology @UMPhysiology on X.
Scientific illustration of gliobastoma cells in the brain
Health Lab
Path forward for glioblastoma treatment
Experts in brain cancer outline current discoveries and offer a path of hope for glioblastoma treatment
Illustration of a microscope
Health Lab
Helpful enzymes vanish in many patients with antiphospholipid syndrome
Researchers recently revealed a new mechanism behind antiphospholipid syndrome that the investigators hope will eventually allow treatments to be targeted closer to the source of the problem.
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Health Lab
Researchers discover urine based test to detect head and neck cancer
At-home test can detect tumor DNA fragments in urine samples, providing a non-invasive alternative to traditional blood-based biomarker tests
Close up image of red blood cells moving through veins
Health Lab
Discovery reveals how this common stinky gas is processed to promote blood vessel growth
A new collaborative study, examined the interaction between three naturally occurring gases — nitric oxide (NO), oxygen, and H2S — during generation of new blood vessels, called angiogenesis.
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Health Lab
Everyone plays a role in improving cancer health equity
As guest editor for a themed journal issue, Lori Pierce helps highlight the multiple factors that can make cancer care and prevention more equitable and reduce the burden of this disease for all
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Health Lab
Sickle cell raises COVID risk, but vaccination lags
Vaccination against the coronavirus was much lower in adults and children with sickle cell disease despite a higher risk of severe COVID-19.
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Health Lab
Studying cells to improve medulloblastoma treatment
Research from Michigan Medicine experts is shedding light and potentially expanding options for patients living with an aggressive childhood cancer.
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Health Lab
Gene therapy to treat sickle cell disease
How two newly approved gene therapies, including novel technology CRISPR, may help kids and adults with inherited blood disorders
woman in hospital on left in ICU and the other right side woman standing in jean jacket and black clothes smiling
Health Lab
Brain tumor and car crash survivor aspires to be example for others living with disabilities
A car accident at age 20 left Sahar Mashhour in the intensive care unit for three months. Almost six years later, Mashhour is still pursuing her passions proving that her disability doesn’t limit her ability, but instead helps her see life through a different lens.
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Health Lab
Medication found safe and effective for preventing bleeding in infants with hemophilia A
Infants with hemophilia A who received monoclonal antibody emicizumab experienced few bleeding events and no serious complications, a study suggests.
flies moving sled in snow with person
Health Lab
Gene links exercise endurance, cold tolerance and cellular maintenance in flies
A study in PNAS identifies a protein that, when missing, makes exercising in the cold that much harder—that is, at least in fruit flies.
stethoscope
Health Lab
Genetic mutation linked to adrenal tumor and hypertension
Research from the Department of Molecular & Integrative Physiology at Michigan Medicine identifies a previously unknown genetic mutation that causes the disease called primary aldosteronism in certain populations.
glioma brain scan
Health Lab
Study finds improved survival for incurable brain tumor, providing ‘a crack in the armor’
A potential drug candidate called ONC201 nearly doubled survival for patients with diffuse midline glioma and DIPG.
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Health Lab
Research sheds new light on gene therapy for blood disorders
Research from experts at Michigan Medicine, the Children’s Hospital of Philadelphia and Penn Medicine is breaking ground on new ways of treating blood disorders, such as sickle cell anemia, through gene therapy.