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The Fundamentals
Treating Diabetes & Weight: The Ozempic & Wegovy Effect
Today on The Fundamentals, our guest Dr. Martin Myers, Director of the U-M Elizabeth Weiser Caswell Diabetes Institute, discusses diabetes research in the context of Ozempic, Wegovy, and other drugs that are changing how people think about weight loss. You can learn more about Dr. Myers here, and you can follow the department of molecular and integrative physiology @UMPhysiology on X.
Close up image of red blood cells moving through veins
Health Lab
Discovery reveals how this common stinky gas is processed to promote blood vessel growth
A new collaborative study, examined the interaction between three naturally occurring gases — nitric oxide (NO), oxygen, and H2S — during generation of new blood vessels, called angiogenesis.
Drawing of parent trying to get child's attention who is listening to music on headphones
Health Lab
Are headphones and earbuds exposing your children to noise health risks?
2 in 3 parents in national poll say their child ages 5-12 use personal audio devices; pediatrician offers 4 tips to reduce noise exposure risks
purple all notifications on phone teen sleeping in bed with phone next to them
Health Lab
Study: Average teen received more than 200 app notifications a day
A Michigan Medicine expert explains more of a report’s key findings on cell phone use and how parents can support a healthy use of technology.
flies moving sled in snow with person
Health Lab
Gene links exercise endurance, cold tolerance and cellular maintenance in flies
A study in PNAS identifies a protein that, when missing, makes exercising in the cold that much harder—that is, at least in fruit flies.
stethoscope
Health Lab
Genetic mutation linked to adrenal tumor and hypertension
Research from the Department of Molecular & Integrative Physiology at Michigan Medicine identifies a previously unknown genetic mutation that causes the disease called primary aldosteronism in certain populations.
kids in classroom playing
Health Lab
Sensitive parenting and preschool attendance may promote academic resilience in late preterm infants
Michigan Medicine research tracks academic trajectories of late preterm infants from infancy to kindergarten and identifies developmental risks and how to best promote resilience
dna strand in blue grainy off white background yellow spots
Health Lab
A new regulator of innate immunity identified
One of the most important protein complexes in mammals involved in ERAD is called SEL1L-HRD1. Recent research finds that this protein complex helps regulate another critical protein involved in innate immunity, called STING, at the endoplasmic reticulum.
black room with person visual far away walking towards glowing light
Health Lab
Evidence of conscious-like activity in the dying brain
A Michigan Medicine study provides early evidence of a surge of activity correlated with consciousness in the dying brain.
uterus image felt graphic red
Health Lab
Mouse study hints at specific brain receptor behind PCOS symptoms
Mouse study at Michigan Medicine hints at specific brain receptor behind PCOS symptoms.
fly on green leaf
Health Lab
Fruit flies feast for pleasure as well as necessity
Study reveals the way flies are just like us when it comes to food.
Women in science collage
Health Lab
Scientists explain their passion, offer advice
Early career researchers describe their professional journeys to help inspire women and girls pursue careers in science
Microscope
Health Lab
Studying a protein modification process in worms provides potential insights for human health
Too much of this post-translational modification impacted multiple body systems
Mouse model of human colorectal cancer
Health Lab
High levels of ammonia in colon tumors inhibits T cell growth and response to immunotherapy
In mouse models and serum samples, an FDA-approved drug that lowers ammonia levels made the tumors more sensitive to treatment.