A team of researchers have spent the past eight years looking at better ways to transport organs for donation, specifically hearts, to improve the number of organs that can be used for transplants. They found that using a modified normothermic perfusion system heart preservation was feasible for up to 24 hours.

Today on The Fundamentals, our guest Dr. Martin Myers, Director of the U-M Elizabeth Weiser Caswell Diabetes Institute, discusses diabetes research in the context of Ozempic, Wegovy, and other drugs that are changing how people think about weight loss. You can learn more about Dr. Myers here, and you can follow the department of molecular and integrative physiology @UMPhysiology on X.

A new collaborative study, examined the interaction between three naturally occurring gases — nitric oxide (NO), oxygen, and H2S — during generation of new blood vessels, called angiogenesis.

Elective surgery study shows older adults have concerns about what it will cost them, how much work they’ll miss and whether they’ll catch COVID-19.

Michigan Medicine’s head of cardiac surgery, Gorav Ailawadi, M.D, M.B.A., answers questions about different treatment options for heart valve disease.

Older adults who live in disadvantaged communities are less likely to attend cardiac rehabilitation after common heart procedures, a Michigan Medicine-led study finds.

The vast majority of people who have a minimally invasive heart valve replacement procedure do not participate in recommended cardiac rehabilitation, a Michigan Medicine-led study finds.

A study in PNAS identifies a protein that, when missing, makes exercising in the cold that much harder—that is, at least in fruit flies.

Research from the Department of Molecular & Integrative Physiology at Michigan Medicine identifies a previously unknown genetic mutation that causes the disease called primary aldosteronism in certain populations.

A Michigan Medicine study finds people who participate in cardiac rehabilitation have a decreased risk of death years after surgery, with a trend towards better outcomes in patients who attend more sessions.

Researchers discover new opportunities for preventing kidney injury following cardiac surgery.

As the number of heart transplants performed across the United States continues to grow, surgeons at the U-M Health are taking advantage of technology that could increase its transplant yield by as much as 30%. Transplant surgeons in Ann Arbor completed the health system’s first heart transplant using an organ from a donor who had recently died — a process called donation after circulatory death, or DCD.

One of the most important protein complexes in mammals involved in ERAD is called SEL1L-HRD1. Recent research finds that this protein complex helps regulate another critical protein involved in innate immunity, called STING, at the endoplasmic reticulum.

A Michigan Medicine study provides early evidence of a surge of activity correlated with consciousness in the dying brain.