Stephanie Eid
Research Assistant Professor
109 Zina Pitcher Pl
Ann Arbor, MI 48109
[email protected]

Available to mentor

Stephanie Eid
Research Assistant Professor
  • About
  • Qualifications
  • Research Overview
  • Recent Publications
  • About

    Dr. Stephanie Eid is a Research Assistant Professor in the Neurology Department since July 2022 and has served as the diabetes team leader for the NeuroNetwork for Emerging Therapies at the University of Michigan since January 2019. She received her M.Sc. in physiology in 2012 from the American University of Beirut, Lebanon and then completed a Ph.D. in neuroscience from Paris Descartes University, France, in 2017. She then joined Eva Feldman’s laboratory to pursue postdoctoral work on the contribution of dyslipidemia to diabetic neuropathy. Dr. Eid has a track-record of high-quality publications, has competed successfully for NIH and internal grants, and recently received the NEURODIAB Angelika Bierhaus Prize in Basic Research, the Wolfe Research Prize for Identifying New Causes or Novel Treatment of Axonal Peripheral Neuropathy from the American Neurological Association, and the Peter J. Dyck Prize for excellence of her presented research and innovation in diabetic neuropathy from the Peripheral Nerve Society. She is currently exploring the metabolic interaction of neurons with Schwann cells in neuropathy, beyond the conventional role of Schwann cells in myelination. She is also determining whether lifestyle interventions can improve nerve function in murine models of obesity, type 2 diabetes, and neuropathy. These innovative studies will advance our understanding of prediabetic and diabetic neuropathy and help develop novel targeted therapies for neuropathy treatment.

    • Postdoctoral fellowship
      University of Michigan–Ann Arbor, Neurology, 2022
    • Ph.D.
      Paris Descartes University, Paris, 2017
    • M.Sc.
      American University of Beirut, Beirut, 2012
    • B.Sc.
      Notre Dame University, Zouk Mosbeh, 2009
    Research Overview

    - Peripheral neuropathy in obesity, prediabetes, and diabetes
    - Dyslipidemia as an independent risk factor for the development of peripheral neuropathy
    - The role of Schwann cells in diabetic neuropathy, beyond myelination
    - Developing new murine models of peripheral neuropathy that faithfully recapitulate the human pathology
    - Cellular and molecular mechanisms involved in the onset and progression of diabetic complications including peripheral neuropathy
    - Systems biology for the study of diabetic complications mechanisms in the clinical and experimental settings
    - Lifestyle interventions in the treatment of peripheral neuropathy
    - Redox biology in health and disease

    Recent Publications See All Publications
    • Journal Article
      Transcriptomic analysis of diabetic kidney disease and neuropathy in mouse models of type 1 and type 2 diabetes.
      Elzinga SE, Eid SA, McGregor BA, Jang D-G, Hinder LM, Dauch JR, Hayes JM, Zhang H, Guo K, Pennathur S, Kretzler M, Brosius FC, Koubek EJ, Feldman EL, Hur J. Dis Model Mech, 2023 Oct 1; 16 (10): DOI:10.1242/dmm.050080
      PMID: 37791586
    • Journal Article
      New perspectives in diabetic neuropathy.
      Eid SA, Rumora AE, Beirowski B, Bennett DL, Hur J, Savelieff MG, Feldman EL. Neuron, 2023 Sep 6; 111 (17): 2623 - 2641. DOI:10.1016/j.neuron.2023.05.003
      PMID: 37263266
    • Journal Article
      Dietary interventions improve diabetic kidney disease, but not peripheral neuropathy, in a db/db mouse model of type 2 diabetes.
      Eid SA, O'Brien PD, Kretzler KH, Jang D-G, Mendelson FE, Hayes JM, Carter A, Zhang H, Pennathur S, Brosius FC, Koubek EJ, Feldman EL. FASEB J, 2023 Aug; 37 (8): e23115 DOI:10.1096/fj.202300354R
      PMID: 37490006
    • Journal Article
      Single-cell RNA-seq uncovers novel metabolic functions of Schwann cells beyond myelination.
      Eid SA, Noureldein M, Kim B, Hinder LM, Mendelson FE, Hayes JM, Hur J, Feldman EL. J Neurochem, 2023 Jul; 166 (2): 367 - 388. DOI:10.1111/jnc.15877
      PMID: 37328915
    • Chapter
      Mechanisms of Nerve Injury in Diabetes: Dyslipidemia, Bioenergetics, and Oxidative Damage
      Eid SA, Noureldein M, Savelieff MG, Feldman EL. 2023 Diabetic Neuropathy, 279 - 306. DOI:10.1007/978-3-031-15613-7_16
    • Journal Article
      The conundrum of diabetic neuropathies-Past, present, and future.
      Ang L, Mizokami-Stout K, Eid SA, Elafros M, Callaghan B, Feldman EL, Pop-Busui R. J Diabetes Complications, 2022 Nov; 36 (11): 108334 DOI:10.1016/j.jdiacomp.2022.108334
      PMID: 36306721
    • Journal Article
      Activation of 20-HETE Synthase Triggers Oxidative Injury and Peripheral Nerve Damage in Type 2 Diabetic Mice.
      Haddad M, Eid S, Harb F, Massry MEL, Azar S, Sauleau E-A, Eid AA. J Pain, 2022 Aug; 23 (8): 1371 - 1388. DOI:10.1016/j.jpain.2022.02.011
      PMID: 35339661
    • Presentation
      460-P: Cellular Communication of Schwann Cell Subtypes in Metabolically-Acquired Neuropathy
      EID S, NOURELDEIN MH, MENDELSON F, FELDMAN EL. 2022 Jun 1; DOI:10.2337/db22-460-p