![](https://medschool.umich.edu/sites/default/files/styles/square_1_1/public/2024-01/Mobley-Harry-2023.png?h=34f513d8&itok=4gxJiRWD)
1500 E. Medical Center Drive
Ann Arbor, MI 48109
Available to mentor
![](https://medschool.umich.edu/sites/default/files/styles/square_1_1/public/2024-01/Mobley-Harry-2023.png?h=34f513d8&itok=4gxJiRWD)
Dr. Mobley received his PhD at the University of Louisville School of Medicine and conducted postdoctoral work at the University of Maryland School of Medicine in Biochemistry and Vaccine Development, after which he joined the faculty in the Division of Infectious Diseases and rose to the rank of Professor of Microbiology and Immunology. After 23 years at Maryland, Dr. Mobley was named Chair of the Department of Microbiology and Immunology at the University of Michigan Medical School in 2004, serving in this role until 2019. Dr. Mobley’s research focuses on uropathogenic E. coli and Proteus mirabilis, but has also studied Helicobacter pylori and Gram-negative bacterial species causing bacteremia including E. coli, Klebsiella pneumoniae, Acinetobacter baumannii, Citrobacter freundii, and Serratia marcescens.
Mobley Lab
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BiochemistryUniversity of Maryland School of Medicine, Department of Biological Chemistry, 1984
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Bacterial GeneticsUniversity of Maryland School of Medicine, Center for Vaccine Development, 1984
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PhDUniversity of Louisville School of Medicine, Louisville, 1981
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MSUniversity of Louisville School of Medicine, Louisville, 1977
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BSEmory University School of Medicine, Atlanta, 1975
Molecular mechanisms of bacterial pathogenesis of urinary tract infection and bacteremia; bacterial genetics; E. coli, Proteus mirabilis, Acinetobacter baumannii
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Frick-Cheng AE, Shea AE, Roberts JR, Smith SN, Ohi MD, Mobley HLT. mBio, 2024 Jul 17; 15 (7): e0104824Journal ArticleIron limitation induces motility in uropathogenic E. coli CFT073 partially through action of LpdA.
DOI:10.1128/mbio.01048-24 PMID: 38874412 -
Fleck RC, Stocki JA, Nguyen IB, Walde R, Mobley HLT, Shea AE. Journal of Urology, 2024 May; 211 (5S): e1293Journal ArticlePD63-04 ASYMPTOMATIC BACTERIURIA DIAGNOSTICS FOR LOW RESOURCE SETTINGS USING A MODIFIED WATER QUALITY TEST KIT
DOI:10.1097/01.ju.0001009384.23104.ca.04 -
Mobley H. 2024 Apr 27;PresentationBacteremia Fitness Factors in Gram-Negative Bacilli
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Shea AE, Forsyth VS, Stocki JA, Mitchell TJ, Frick-Cheng AE, Smith SN, Hardy SL, Mobley HLT. Proc Natl Acad Sci U S A, 2024 Apr 16; 121 (16): e2310693121Journal ArticleEmerging roles for ABC transporters as virulence factors in uropathogenic Escherichia coli.
DOI:10.1073/pnas.2310693121 PMID: 38607934 -
Fitzgerald MJ, Pearson MM, Mobley HLT. J Bacteriol, 2024 Apr 18; 206 (4): e0003124Journal ArticleProteus mirabilis UreR coordinates cellular functions required for urease activity.
DOI:10.1128/jb.00031-24 PMID: 38534115 -
Mobley HLT, Anderson MT, Moricz BS, Severin GB, Holmes CL, Ottosen EN, Eichler T, Gupta S, Paudel S, Sinha R, Mason S, Himpsl SD, Brown AN, Gaca M, Kiser CM, Clarke TH, Fouts DE, DiRita VJ, Bachman MA. bioRxiv,PreprintFitness Factor Genes Conserved within the Multi-species Core Genome of Gram-negative Enterobacterales Species Contribute to Bacteremia Pathogenesis
DOI:10.1101/2024.03.18.585282 -
Pearson MM, Shea AE, Pahil S, Smith SN, Forsyth VS, Mobley HLT. Infect Immun, 2023 Nov 16; 91 (11): e0035523Journal ArticleOrgan agar serves as physiologically relevant alternative for in vivo bacterial colonization.
DOI:10.1128/iai.00355-23 PMID: 37850748 -
Brown AN, Anderson MT, Smith SN, Bachman MA, Mobley HLT. mBio, 2023 Oct 31; 14 (5): e0144823Journal ArticleConserved metabolic regulator ArcA responds to oxygen availability, iron limitation, and cell envelope perturbations during bacteremia.
DOI:10.1128/mbio.01448-23 PMID: 37681955
![Left to right: Surbhi Gupta (University of Michigan), Laura Mike (University of Pittsburgh), Harry Mobley (University of Michigan), Melanie Pearson (University of Michigan), Chelsie Armbruster (SUNY Buffalo), and Allyson Shea (University of South Alabama)](https://medschool.umich.edu/sites/default/files/styles/card/public/2024-07/mobley_diaspora_utiga_july_2024-vignette.jpg?h=f81798d5&itok=4tzPYDQU)