Denise O Leung, MD, MSc
Associate Professor of Neurology
[email protected]

Available to mentor
Denise O Leung, MD, MSc
Clinical Associate Professor
  • Qualifications
  • Center Memberships
  • Recent Publications
    • Qualifications
    • Neuro-Oncology Fellow
      Henry Ford Hospital, United States, 2014
    • Neurology Resident
      Henry Ford Hospital, Neurology, 2012
    • Transitional Year Resident
      Henry Ford Hospital, United States, 2009
    Center Memberships
    • Center Member
      Precision Health Initiative
    Recent Publications See All Publications
    • Journal Article
      Practical guidance for direct oral anticoagulant use in the treatment of venous thromboembolism in primary and metastatic brain tumor patients.
      Ranjan S, Leung D, Ghiaseddin AP, Taylor JW, Lobbous M, Dhawan A, Budhu JA, Coffee E, Melnick K, Chowdhary SA, Lu-Emerson C, Kurz SC, Burke JE, Lam K, Patel MP, Dunbar EM, Mohile NA, Peters KB. Cancer, 2024 May 1; 130 (9): 1577 - 1589. DOI:10.1002/cncr.35220
      PMID: 38288941
    • Proceeding / Abstract / Poster
      CTNI-61. MYCOPHENOLATE MOFETIL INHIBITS GLIOBLASTOMA PURINE METABOLISM IN HUMANS: AN INTERIM RESULT OF PHASE 0/1 CLINICAL TRIAL TO OVERCOME TREATMENT RESISTANCE IN NEWLY DIAGNOSED AND RECURRENT GLIOBLASTOMA
      Umemura Y, Al-Holou W, Elaimy A, Scott AJ, Leung D, Clarke N, Kim MM, Ferris S, Thomas J, Heth J, Schipper M, Suresh K, Lawrence T, Wahl D. Neuro-Oncology, 2023 Nov 10; 25 (Supplement_5): v90 - v90. DOI:10.1093/neuonc/noad179.0343
    • Journal Article
      Metabolomic Profiles of Human Glioma Inform Patient Survival.
      Scott AJ, Correa LO, Edwards DM, Sun Y, Ravikumar V, Andren AC, Zhang L, Srinivasan S, Jairath N, Verbal K, Muraszko K, Sagher O, Carty SA, Hervey-Jumper S, Orringer D, Kim MM, Junck L, Umemura Y, Leung D, Venneti S, Camelo-Piragua S, Lawrence TS, Ippolito JE, Al-Holou WN, Chinnaiyan P, Heth J, Rao A, Lyssiotis CA, Wahl DR. Antioxid Redox Signal, 2023 Nov; 39 (13-15): 942 - 956. DOI:10.1089/ars.2022.0085
      PMID: 36852494
    • Journal Article
      Combined cytotoxic and immune-stimulatory gene therapy for primary adult high-grade glioma: a phase 1, first-in-human trial.
      Umemura Y, Orringer D, Junck L, Varela ML, West MEJ, Faisal SM, Comba A, Heth J, Sagher O, Leung D, Mammoser A, Hervey-Jumper S, Zamler D, Yadav VN, Dunn P, Al-Holou W, Hollon T, Kim MM, Wahl DR, Camelo-Piragua S, Lieberman AP, Venneti S, McKeever P, Lawrence T, Kurokawa R, Sagher K, Altshuler D, Zhao L, Muraszko K, Castro MG, Lowenstein PR. Lancet Oncol, 2023 Sep; 24 (9): 1042 - 1052. DOI:10.1016/S1470-2045(23)00347-9
      PMID: 37657463
    • Journal Article
      A Call to Advocacy: The Role of The Neurologist and Neuro-oncologist (Op-Ed)
      Budhu J, Bhatia A, Burke J, Chowdhary S, Coffee E, Daras M, Dhawan A, Dunbar E, Ghiaseddin A, Kurz S, Lam K, Leeper H, Leung D, Lobbous M, Lu-Emerson C, Mohile N, Peters KB, Ranjan S, Sharma A, Taylor J. Neurology Blogs,
    • Journal Article
      A Call to Advocacy: The Role of The Neurologist and Neuro-oncologist (Op-Ed)
      Budhu J, Bhatia A, Burke J, Chowdhary S, Coffee E, Daras M, Dhawan A, Dunbar E, Ghiaseddin A, Kurz S, Lam K, Leeper H, Leung D, Lobbous M, Lu-Emerson C, Mohile N, Peters KB, Ranjan S, Sharma A, Taylor J. Neurology Blogs,
    • Proceeding / Abstract / Poster
      Abstract 1093: Measuring and inhibiting purine metabolism in patients with glioblastoma
      Umemura Y, Scott AJ, Al-Holou W, Mittal A, Zhou W, Wilder-Romans K, Xu J, Qi N, Kachman M, Kim M, Junck L, Leung D, Clarke N, Heth J, Wen B, Pai A, Tarnal V, Nagrath D, Lawrence T, Lyssiotis CA, Wahl DR. Cancer Research, 2023 Apr 4; 83 (7_Supplement): 1093 - 1093. DOI:10.1158/1538-7445.am2023-1093
    • Journal Article
      IMPACT the Brain: A Team-Based Approach to Management of Metastatic Breast Cancer With CNS Metastases.
      Fleege NMG, Pierce-Gjeldum D, Swartz LK, Verbal K, Merajver S, Friese CR, Kiyota A, Heth J, Leung D, Smith SR, Gabel N, Kim MM, Morikawa A. JCO Oncol Pract, 2023 Jan; 19 (1): e67 - e77. DOI:10.1200/OP.22.00291
      PMID: 36223556