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graphic of three people standing next to eachother and DNA strip over them in yellow
Health Lab
Sex, age, mental health and more can affect perceived barriers to genetic testing for cancer
A variety of factors affect the barriers that patients with cancer foresee to undergoing genetic testing, researchers found, but the issues that motivate patients to actually follow through with genetic testing remain unclear.
Health Lab
Study offers clues to how cancer spreads to the brain
Michigan Medicine researchers used microfluidic devices to track what happens to cancer cells as they migrate and take root in the brain.
 backs of three people
Health Lab
When genetic testing can help the whole family
Genetic testing for hereditary conditions such as breast cancer can have implications for the whole family. Learn how genetic testing helped Cathleen Argyle and her family to uncover a rare mutation and how the Rogel Cancer Center provided advice and guidance throughout the process.
 cancer cell
Health Lab
Artificial intelligence predicts genetics of cancerous brain tumors in under 90 seconds
A new study finds AI-based diagnostic screening system, DeepGlioma, detects genetic mutations in brain tumors in under 90 seconds. Streamlining glioma diagnosis and treatment.
 person with stomach pain purple and grey coloring and at home stool test
Health Lab
When to use an at-home colorectal cancer screening test instead of a colonoscopy
What to know about an at-home colorectal cancer screening test versus a colonoscopy
 blues gloves in lab samples container
Health Lab
“Cell food” gives insight into T cell metabolism
By feeding T cells in the lab, researchers revealed a new metabolic pathway that could help make immunology more effective.
 Cancer protein Stat5 cell yellow
Health Lab
Researchers use a new approach to hit an ‘undruggable’ target
Protein degrader shows promise against STAT5, which plays a role in leukemia and other cancers
 Graphic of red and white blood cells in a vein
Health Lab
An unexpected “junk” discovery
Russell Ryan, MD, and his team’s discovery appears to address longstanding mysteries about mutations found in B-cell acute lymphoblastic leukemia
News Release
University of Michigan Medical School withdraws from participating in U.S. News & World Report annual rankings
The University of Michigan Medical School will no longer participate in the annual U.S. News & World Report (USNWR) rankings of medical schools.
 microscope cells glioma
Health Lab
Researchers circumvent radiation resistance in subtype of brain tumors
University of Michigan Rogel Cancer Center researchers find ZMYND8 gene plays a critical role in conferring radiation resistance on brain tumors with IDH1 mutation.
 Cancer Aware surrounded by a circle of multicolor ribbons
Cancer Aware
Lumpectomy vs. Mastectomy
Dr. Melissa Pilewskie, U-M Health Rogel Cancer Center surgical oncologist, discusses the two main surgical options for treating breast cancer.
 cancer cells microscope blue green
Health Lab
Certain gene signaling rewires tumors after immunotherapy
For some patients, immunotherapy furthers tumor progression instead of halting it. What distinguishes those who benefit from those who don’t?
 machine green laser grid metal
Health Lab
Tracking radiation treatment in real time promises safer, more effective cancer therapy
Radiation, used to treat half of all cancer patients, can be measured during treatment for the first time with precise 3D imaging developed at the University of Michigan.
 blue cells, gut with sushi, face mask and more in a collage
Health Lab
Michigan Health Lab’s most read articles of 2022
The year provided one fascinating research story after another.
 Mouse model of human colorectal cancer
Health Lab
High levels of ammonia in colon tumors inhibits T cell growth and response to immunotherapy
In mouse models and serum samples, an FDA-approved drug that lowers ammonia levels made the tumors more sensitive to treatment.
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